TM7SF3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034620Biological processcellular response to unfolded protein
GO_0043069Biological processnegative regulation of programmed cell death
GO_0032024Biological processpositive regulation of insulin secretion
GO_0070062Cellular componentextracellular exosome
GO_0005886Cellular componentplasma membrane
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameTM7SF3
Protein nameTransmembrane 7 superfamily member 3
Transmembrane 7 superfamily member 3 (Seven span transmembrane protein)
Synonyms
DescriptionFUNCTION: Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells . Is a downstream transcriptional target of p53/TP53, and acts as a pro-survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR) . .

AccessionsENST00000543655.5
ENST00000539741.5
F5H4T1
ENST00000543803.5
H0YFT0
ENST00000512808.2
H0YFW7
H0YGR1
F5H587
ENST00000545344.5
ENST00000545600.1
ENST00000343028.9
F5H7C5
H0YFM3
F5H3K5
ENST00000543088.5
ENST00000535423.5
H0YH23
F5GWC3
ENST00000537406.1
ENST00000542019.1
F5GY59
F5GXE1
ENST00000535260.5
ENST00000535819.1
ENST00000545303.5
F5GY35
ENST00000543882.5
Q9NS93