TM2D3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	12 studies	24% ± 6%	Explore
fibroblast	11 studies	24% ± 7%	Explore
oligodendrocyte	7 studies	23% ± 4%	Explore
epithelial cell	6 studies	32% ± 14%	Explore
astrocyte	6 studies	22% ± 7%	Explore
regulatory T cell	6 studies	18% ± 4%	Explore
CD4-positive, alpha-beta T cell	5 studies	20% ± 2%	Explore
natural killer cell	5 studies	18% ± 3%	Explore
ciliated cell	5 studies	23% ± 7%	Explore
T follicular helper cell	5 studies	17% ± 1%	Explore
GABAergic neuron	5 studies	41% ± 18%	Explore
basal cell	5 studies	27% ± 8%	Explore
connective tissue cell	4 studies	28% ± 6%	Explore
pericyte	4 studies	23% ± 4%	Explore
endothelial cell of vascular tree	4 studies	17% ± 2%	Explore
retina horizontal cell	4 studies	28% ± 12%	Explore
macrophage	4 studies	18% ± 3%	Explore
glutamatergic neuron	4 studies	51% ± 14%	Explore
oligodendrocyte precursor cell	4 studies	27% ± 2%	Explore
CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
gamma-delta T cell	4 studies	21% ± 6%	Explore
interneuron	4 studies	39% ± 21%	Explore
neuron	4 studies	35% ± 11%	Explore
pancreatic A cell	3 studies	36% ± 10%	Explore
type B pancreatic cell	3 studies	40% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	17% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	18% ± 1%	Explore
classical monocyte	3 studies	17% ± 1%	Explore
conventional dendritic cell	3 studies	19% ± 3%	Explore
capillary endothelial cell	3 studies	19% ± 2%	Explore
mucosal invariant T cell	3 studies	17% ± 1%	Explore
myofibroblast cell	3 studies	19% ± 3%	Explore
smooth muscle cell	3 studies	21% ± 3%	Explore
B cell	3 studies	17% ± 1%	Explore
endothelial cell of lymphatic vessel	3 studies	26% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	17% ± 1%	Explore
naive B cell	3 studies	17% ± 3%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	7 studies	32% ± 16%	Explore
lung	5 studies	24% ± 4%	Explore
pancreas	3 studies	35% ± 9%	Explore
eye	3 studies	24% ± 7%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1961.13	1445 / 1445	100%	7.55	183 / 183
lung	100%	2283.23	578 / 578	100%	10.71	1155 / 1155
prostate	100%	2163.67	245 / 245	100%	11.79	502 / 502
stomach	100%	1814.71	359 / 359	100%	7.95	286 / 286
uterus	100%	2910.46	170 / 170	100%	11.45	459 / 459
brain	100%	3540.75	2641 / 2642	100%	17.92	705 / 705
kidney	100%	1897.45	89 / 89	100%	10.77	900 / 901
thymus	100%	2931.69	653 / 653	100%	16.26	604 / 605
breast	100%	2312.59	459 / 459	100%	11.79	1116 / 1118
bladder	100%	2191.71	21 / 21	100%	9.36	503 / 504
intestine	100%	2359.46	966 / 966	100%	8.91	525 / 527
adrenal gland	100%	2194.22	258 / 258	100%	17.07	229 / 230
ovary	100%	3351.10	180 / 180	100%	8.86	428 / 430
liver	100%	2047.32	226 / 226	100%	8.68	404 / 406
pancreas	99%	1282.46	326 / 328	100%	10.66	178 / 178
skin	100%	1913.76	1808 / 1809	99%	9.74	468 / 472
adipose	100%	2319.07	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2746.61	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	10.95	29 / 29
muscle	100%	1982.93	803 / 803	0%	0	0 / 0
spleen	100%	2407.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	8.25	45 / 45
ureter	0%	0	0 / 0	100%	5.62	1 / 1
heart	99%	1789.18	855 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	6.61	78 / 80
peripheral blood	92%	1506.98	859 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0