THAP11 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030182Biological processneuron differentiation
GO_0022900Biological processelectron transport chain
GO_0008283Biological processcell population proliferation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0043524Biological processnegative regulation of neuron apoptotic process
GO_1903108Biological processregulation of mitochondrial transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameTHAP11
Protein nameTHAP domain-containing protein 11
THAP domain containing 11
SynonymsHRIHFB2206
DescriptionFUNCTION: Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity). .

AccessionsB5APZ3
Q96EK4
ENST00000303596.3