TBC1D4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016192Biological processvesicle-mediated transport
GO_0031339Biological processnegative regulation of vesicle fusion
GO_0032869Biological processcellular response to insulin stimulus
GO_0090630Biological processactivation of GTPase activity
GO_0005829Cellular componentcytosol
GO_0031982Cellular componentvesicle
GO_0005515Molecular functionprotein binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameTBC1D4
Protein nameTBC1 domain family member 4
TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160)
SynonymsKIAA0603
AS160
DescriptionFUNCTION: May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake. .

AccessionsENST00000413735.1
ENST00000431480.6 [O60343-3]
ENST00000377625.6 [O60343-2]
Q5JU47
O60343
ENST00000377636.8 [O60343-1]
A0A3B3IRT3
ENST00000648194.1