Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 24 studies | 38% ± 20% | |
| regulatory T cell | 22 studies | 33% ± 11% | |
| microglial cell | 11 studies | 45% ± 13% | |
| dendritic cell | 9 studies | 39% ± 13% | |
| adipocyte | 8 studies | 44% ± 11% | |
| fibroblast | 8 studies | 25% ± 9% | |
| macrophage | 8 studies | 33% ± 11% | |
| glutamatergic neuron | 7 studies | 40% ± 20% | |
| GABAergic neuron | 7 studies | 45% ± 22% | |
| interneuron | 6 studies | 45% ± 18% | |
| cardiac muscle cell | 6 studies | 57% ± 24% | |
| plasmacytoid dendritic cell | 6 studies | 20% ± 4% | |
| neuron | 5 studies | 35% ± 24% | |
| pericyte | 5 studies | 26% ± 6% | |
| kidney loop of Henle epithelial cell | 5 studies | 39% ± 21% | |
| T follicular helper cell | 5 studies | 26% ± 9% | |
| type II pneumocyte | 5 studies | 30% ± 7% | |
| myeloid cell | 4 studies | 21% ± 6% | |
| endothelial cell of lymphatic vessel | 4 studies | 25% ± 3% | |
| astrocyte | 4 studies | 28% ± 17% | |
| oligodendrocyte precursor cell | 4 studies | 23% ± 3% | |
| ionocyte | 3 studies | 37% ± 5% | |
| CD4-positive, alpha-beta T cell | 3 studies | 19% ± 3% | |
| GABAergic interneuron | 3 studies | 26% ± 8% | |
| epithelial cell | 3 studies | 20% ± 3% | |
| basal cell | 3 studies | 19% ± 2% | |
| kidney distal convoluted tubule epithelial cell | 3 studies | 30% ± 8% | |
| renal alpha-intercalated cell | 3 studies | 55% ± 23% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 4635.40 | 459 / 459 | 99% | 22.54 | 1102 / 1118 |
| kidney | 100% | 4449.55 | 89 / 89 | 98% | 27.84 | 879 / 901 |
| esophagus | 98% | 2219.02 | 1422 / 1445 | 99% | 22.53 | 181 / 183 |
| prostate | 97% | 3398.83 | 238 / 245 | 100% | 39.62 | 500 / 502 |
| adrenal gland | 100% | 20761.69 | 258 / 258 | 96% | 23.51 | 221 / 230 |
| pancreas | 99% | 1905.29 | 325 / 328 | 96% | 13.76 | 171 / 178 |
| thymus | 100% | 6596.88 | 653 / 653 | 94% | 16.49 | 567 / 605 |
| lung | 98% | 2584.61 | 567 / 578 | 95% | 13.88 | 1096 / 1155 |
| skin | 100% | 4540.33 | 1808 / 1809 | 93% | 37.35 | 439 / 472 |
| brain | 94% | 1578.19 | 2485 / 2642 | 97% | 11.60 | 686 / 705 |
| stomach | 94% | 2444.36 | 339 / 359 | 95% | 23.36 | 272 / 286 |
| uterus | 100% | 2573.64 | 170 / 170 | 87% | 12.82 | 401 / 459 |
| bladder | 95% | 1791.76 | 20 / 21 | 91% | 14.64 | 458 / 504 |
| intestine | 85% | 1949.07 | 820 / 966 | 97% | 24.23 | 512 / 527 |
| ovary | 100% | 9360.51 | 180 / 180 | 60% | 4.72 | 260 / 430 |
| liver | 88% | 1168.97 | 199 / 226 | 65% | 7.63 | 265 / 406 |
| adipose | 100% | 4050.15 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 12749.33 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4610.42 | 241 / 241 | 0% | 0 | 0 / 0 |
| heart | 97% | 5482.01 | 837 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 28.24 | 75 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 14.55 | 39 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 26.31 | 25 / 29 |
| blood vessel | 82% | 1280.64 | 1094 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 30% | 897.39 | 280 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016192 | Biological process | vesicle-mediated transport |
| GO_0031339 | Biological process | negative regulation of vesicle fusion |
| GO_0032869 | Biological process | cellular response to insulin stimulus |
| GO_0090630 | Biological process | activation of GTPase activity |
| GO_0005829 | Cellular component | cytosol |
| GO_0031982 | Cellular component | vesicle |
| GO_0005515 | Molecular function | protein binding |
| GO_0005096 | Molecular function | GTPase activator activity |
| Gene name | TBC1D4 |
| Protein name | TBC1 domain family member 4 TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160) |
| Synonyms | KIAA0603 AS160 |
| Description | FUNCTION: May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake. . |
| Accessions | ENST00000413735.1 ENST00000431480.6 [O60343-3] ENST00000377625.6 [O60343-2] Q5JU47 O60343 ENST00000377636.8 [O60343-1] A0A3B3IRT3 ENST00000648194.1 |