Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 31 studies | 44% ± 18% | |
| fibroblast | 30 studies | 33% ± 15% | |
| endothelial cell | 26 studies | 38% ± 17% | |
| endothelial cell of lymphatic vessel | 17 studies | 34% ± 15% | |
| pericyte | 14 studies | 36% ± 15% | |
| basal cell | 13 studies | 40% ± 20% | |
| adipocyte | 10 studies | 46% ± 15% | |
| type I pneumocyte | 9 studies | 39% ± 18% | |
| non-classical monocyte | 9 studies | 26% ± 11% | |
| myofibroblast cell | 9 studies | 41% ± 23% | |
| epithelial cell | 9 studies | 34% ± 19% | |
| ciliated cell | 9 studies | 28% ± 9% | |
| endothelial cell of vascular tree | 9 studies | 26% ± 9% | |
| GABAergic neuron | 8 studies | 30% ± 14% | |
| connective tissue cell | 8 studies | 32% ± 16% | |
| capillary endothelial cell | 7 studies | 23% ± 7% | |
| alveolar macrophage | 7 studies | 37% ± 19% | |
| macrophage | 6 studies | 31% ± 23% | |
| interneuron | 6 studies | 33% ± 14% | |
| neuron | 6 studies | 31% ± 16% | |
| cardiac muscle cell | 6 studies | 81% ± 15% | |
| type II pneumocyte | 6 studies | 38% ± 11% | |
| monocyte | 6 studies | 42% ± 23% | |
| club cell | 6 studies | 39% ± 13% | |
| myeloid cell | 5 studies | 22% ± 8% | |
| vein endothelial cell | 5 studies | 38% ± 20% | |
| classical monocyte | 4 studies | 21% ± 3% | |
| Mueller cell | 4 studies | 36% ± 5% | |
| retinal cone cell | 4 studies | 36% ± 12% | |
| retinal rod cell | 4 studies | 22% ± 6% | |
| astrocyte | 4 studies | 36% ± 12% | |
| muscle cell | 4 studies | 64% ± 31% | |
| glutamatergic neuron | 4 studies | 46% ± 8% | |
| myoepithelial cell | 4 studies | 47% ± 27% | |
| neutrophil | 3 studies | 28% ± 9% | |
| Purkinje cell | 3 studies | 65% ± 21% | |
| microglial cell | 3 studies | 61% ± 28% | |
| progenitor cell | 3 studies | 34% ± 10% | |
| lymphocyte | 3 studies | 26% ± 12% | |
| ON-bipolar cell | 3 studies | 27% ± 2% | |
| retinal ganglion cell | 3 studies | 54% ± 14% | |
| abnormal cell | 3 studies | 24% ± 10% | |
| cholangiocyte | 3 studies | 50% ± 19% | |
| hepatocyte | 3 studies | 57% ± 29% | |
| oligodendrocyte precursor cell | 3 studies | 26% ± 9% | |
| dendritic cell | 3 studies | 19% ± 1% | |
| adventitial cell | 3 studies | 32% ± 8% | |
| respiratory goblet cell | 3 studies | 37% ± 15% | |
| goblet cell | 3 studies | 39% ± 26% | |
| transit amplifying cell | 3 studies | 41% ± 28% | |
| mucus secreting cell | 3 studies | 43% ± 14% | |
| secretory cell | 3 studies | 26% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 94% | 41823.65 | 1364 / 1445 | 99% | 43.60 | 182 / 183 |
| uterus | 97% | 29053.42 | 165 / 170 | 95% | 31.67 | 437 / 459 |
| ovary | 100% | 17960.37 | 180 / 180 | 89% | 14.63 | 384 / 430 |
| bladder | 90% | 50710.90 | 19 / 21 | 93% | 22.08 | 468 / 504 |
| thymus | 85% | 8122.25 | 552 / 653 | 98% | 39.16 | 591 / 605 |
| prostate | 83% | 16424.67 | 203 / 245 | 98% | 33.34 | 494 / 502 |
| intestine | 78% | 57045.54 | 758 / 966 | 96% | 18.59 | 506 / 527 |
| breast | 66% | 6460.30 | 305 / 459 | 97% | 24.32 | 1083 / 1118 |
| skin | 57% | 5194.84 | 1039 / 1809 | 93% | 22.09 | 438 / 472 |
| lung | 48% | 3894.48 | 276 / 578 | 98% | 29.84 | 1127 / 1155 |
| stomach | 44% | 21298.76 | 158 / 359 | 96% | 26.88 | 275 / 286 |
| kidney | 12% | 921.40 | 11 / 89 | 91% | 20.00 | 822 / 901 |
| muscle | 100% | 141747.56 | 803 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 28.27 | 45 / 45 |
| blood vessel | 100% | 34098.73 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 1% | 102.52 | 4 / 328 | 97% | 25.88 | 172 / 178 |
| heart | 88% | 19786.56 | 755 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 6% | 413.47 | 15 / 258 | 75% | 13.27 | 172 / 230 |
| liver | 0% | 0 | 0 / 226 | 59% | 7.34 | 238 / 406 |
| eye | 0% | 0 | 0 / 0 | 55% | 5.62 | 44 / 80 |
| adipose | 40% | 3978.31 | 479 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 34% | 2.41 | 10 / 29 |
| peripheral blood | 16% | 1328.19 | 151 / 929 | 0% | 0 | 0 / 0 |
| brain | 0% | 5.14 | 2 / 2642 | 16% | 1.68 | 113 / 705 |
| spleen | 1% | 68.07 | 2 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007519 | Biological process | skeletal muscle tissue development |
| GO_0051016 | Biological process | barbed-end actin filament capping |
| GO_0008154 | Biological process | actin polymerization or depolymerization |
| GO_0051014 | Biological process | actin filament severing |
| GO_0032467 | Biological process | positive regulation of cytokinesis |
| GO_0030496 | Cellular component | midbody |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043034 | Cellular component | costamere |
| GO_0036449 | Cellular component | microtubule minus-end |
| GO_0002102 | Cellular component | podosome |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0015629 | Cellular component | actin cytoskeleton |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0042995 | Cellular component | cell projection |
| GO_0032154 | Cellular component | cleavage furrow |
| GO_0005634 | Cellular component | nucleus |
| GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SVIL |
| Protein name | Alternative protein SVIL Supervillin Supervillin (Archvillin) (p205/p250) SVIL protein |
| Synonyms | |
| Description | FUNCTION: [Isoform 1]: Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation . Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function . .; FUNCTION: [Isoform 2]: May be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity). . |
| Accessions | ENST00000375400.7 [O95425-2] ENST00000674475.1 Q569J5 L0R8G3 ENST00000375398.6 [O95425-4] A0A6I8PIX7 A0A0J9YWY6 O95425 A0A6I8PL75 ENST00000674242.1 ENST00000355867.9 [O95425-1] ENST00000632315.1 |