SRGAP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0030336Biological processnegative regulation of cell migration
GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_0005829Cellular componentcytosol
GO_0098794Cellular componentpostsynapse
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameSRGAP3
Protein nameSLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)
SRGAP3
SRGAP3 protein
SynonymsARHGAP14
KIAA0411
SRGAP2
KIAA1156
MEGAP
DescriptionFUNCTION: GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons. .

AccessionsO43295
Q8IXS7
ENST00000383836.8 [O43295-1]
ENST00000360413.7 [O43295-2]
A0A2X0U4U8