Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| neuron | 6 studies | 38% ± 19% | |
| endothelial cell | 5 studies | 33% ± 10% | |
| GABAergic neuron | 4 studies | 39% ± 17% | |
| neural crest cell | 3 studies | 36% ± 15% | |
| pericyte | 3 studies | 22% ± 1% | |
| smooth muscle cell | 3 studies | 21% ± 4% | |
| interneuron | 3 studies | 34% ± 8% | |
| glutamatergic neuron | 3 studies | 35% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 92% | 348.68 | 2420 / 2642 | 96% | 27.51 | 679 / 705 |
| spleen | 73% | 68.71 | 175 / 241 | 0% | 0 | 0 / 0 |
| intestine | 70% | 276.57 | 673 / 966 | 2% | 0.08 | 11 / 527 |
| heart | 67% | 91.60 | 574 / 861 | 0% | 0 | 0 / 0 |
| breast | 21% | 19.10 | 97 / 459 | 31% | 6.13 | 351 / 1118 |
| esophagus | 44% | 45.33 | 631 / 1445 | 8% | 0.41 | 14 / 183 |
| ovary | 0% | 0 | 0 / 180 | 28% | 5.70 | 120 / 430 |
| skin | 18% | 30.83 | 320 / 1809 | 8% | 4.43 | 39 / 472 |
| stomach | 18% | 24.91 | 66 / 359 | 3% | 0.29 | 10 / 286 |
| kidney | 0% | 0 | 0 / 89 | 21% | 1.30 | 191 / 901 |
| lung | 6% | 3.76 | 35 / 578 | 11% | 1.58 | 130 / 1155 |
| thymus | 9% | 8.26 | 59 / 653 | 5% | 0.53 | 33 / 605 |
| uterus | 1% | 0.23 | 1 / 170 | 14% | 3.71 | 63 / 459 |
| pancreas | 0% | 0 | 0 / 328 | 11% | 0.66 | 19 / 178 |
| adrenal gland | 0% | 0 | 0 / 258 | 10% | 0.62 | 24 / 230 |
| muscle | 7% | 4.92 | 55 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.19 | 3 / 45 |
| bladder | 0% | 0 | 0 / 21 | 5% | 0.46 | 26 / 504 |
| peripheral blood | 3% | 4.70 | 31 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 2% | 2.02 | 32 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 1% | 0.34 | 2 / 245 | 1% | 0.03 | 4 / 502 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.06 | 3 / 406 |
| adipose | 0% | 0.32 | 4 / 1204 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0017015 | Biological process | regulation of transforming growth factor beta receptor signaling pathway |
| GO_0014003 | Biological process | oligodendrocyte development |
| GO_0003151 | Biological process | outflow tract morphogenesis |
| GO_0021510 | Biological process | spinal cord development |
| GO_0048485 | Biological process | sympathetic nervous system development |
| GO_0010629 | Biological process | negative regulation of gene expression |
| GO_0061303 | Biological process | cornea development in camera-type eye |
| GO_0048593 | Biological process | camera-type eye morphogenesis |
| GO_0061386 | Biological process | closure of optic fissure |
| GO_0048704 | Biological process | embryonic skeletal system morphogenesis |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0050769 | Biological process | positive regulation of neurogenesis |
| GO_0001822 | Biological process | kidney development |
| GO_2000648 | Biological process | positive regulation of stem cell proliferation |
| GO_0050672 | Biological process | negative regulation of lymphocyte proliferation |
| GO_0003357 | Biological process | noradrenergic neuron differentiation |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0045669 | Biological process | positive regulation of osteoblast differentiation |
| GO_0060023 | Biological process | soft palate development |
| GO_0035332 | Biological process | positive regulation of hippo signaling |
| GO_0030182 | Biological process | neuron differentiation |
| GO_2001111 | Biological process | positive regulation of lens epithelial cell proliferation |
| GO_2000678 | Biological process | negative regulation of transcription regulatory region DNA binding |
| GO_0060425 | Biological process | lung morphogenesis |
| GO_0060253 | Biological process | negative regulation of glial cell proliferation |
| GO_0060563 | Biological process | neuroepithelial cell differentiation |
| GO_0048557 | Biological process | embryonic digestive tract morphogenesis |
| GO_0030513 | Biological process | positive regulation of BMP signaling pathway |
| GO_0060412 | Biological process | ventricular septum morphogenesis |
| GO_0060022 | Biological process | hard palate development |
| GO_0007420 | Biological process | brain development |
| GO_0002089 | Biological process | lens morphogenesis in camera-type eye |
| GO_0035914 | Biological process | skeletal muscle cell differentiation |
| GO_0045666 | Biological process | positive regulation of neuron differentiation |
| GO_0045778 | Biological process | positive regulation of ossification |
| GO_0046887 | Biological process | positive regulation of hormone secretion |
| GO_0061029 | Biological process | eyelid development in camera-type eye |
| GO_0007399 | Biological process | nervous system development |
| GO_0014009 | Biological process | glial cell proliferation |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0000976 | Molecular function | transcription cis-regulatory region binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| Gene name | SOX11 |
| Protein name | Transcription factor SOX-11 Alternative protein SOX11 SOX11 protein |
| Synonyms | |
| Description | FUNCTION: Transcription factor that acts as a transcriptional activator . Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity). . |
| Accessions | Q05CH0 L8E7T1 P35716 ENST00000322002.5 |
