Insufficient scRNA-seq data for expression of SOX1 at single-cell level.
Insufficient scRNA-seq data for expression of SOX1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 97% | 331.61 | 2574 / 2642 | 88% | 9.30 | 622 / 705 |
eye | 0% | 0 | 0 / 0 | 99% | 37.09 | 79 / 80 |
intestine | 7% | 4.17 | 69 / 966 | 25% | 1.60 | 133 / 527 |
skin | 2% | 1.11 | 40 / 1809 | 26% | 2.34 | 121 / 472 |
stomach | 0% | 0 | 0 / 359 | 17% | 0.76 | 49 / 286 |
tonsil | 0% | 0 | 0 / 0 | 16% | 0.47 | 7 / 45 |
esophagus | 0% | 0.11 | 3 / 1445 | 15% | 0.53 | 27 / 183 |
lung | 0% | 0.07 | 1 / 578 | 7% | 0.30 | 78 / 1155 |
bladder | 0% | 0 | 0 / 21 | 7% | 0.43 | 34 / 504 |
uterus | 0% | 0 | 0 / 170 | 4% | 0.19 | 19 / 459 |
adrenal gland | 0% | 0 | 0 / 258 | 4% | 0.12 | 9 / 230 |
thymus | 0% | 0 | 0 / 653 | 2% | 0.14 | 15 / 605 |
liver | 0% | 0 | 0 / 226 | 2% | 0.16 | 7 / 406 |
kidney | 0% | 0 | 0 / 89 | 2% | 0.04 | 15 / 901 |
prostate | 0% | 0 | 0 / 245 | 1% | 0.03 | 6 / 502 |
pancreas | 0% | 0 | 0 / 328 | 1% | 0.12 | 1 / 178 |
breast | 0% | 0 | 0 / 459 | 0% | 0.02 | 4 / 1118 |
adipose | 0% | 0.05 | 1 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006325 | Biological process | chromatin organization |
GO_1990830 | Biological process | cellular response to leukemia inhibitory factor |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0030182 | Biological process | neuron differentiation |
GO_1904936 | Biological process | interneuron migration |
GO_0021521 | Biological process | ventral spinal cord interneuron specification |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0021884 | Biological process | forebrain neuron development |
GO_0048713 | Biological process | regulation of oligodendrocyte differentiation |
GO_0007420 | Biological process | brain development |
GO_0002089 | Biological process | lens morphogenesis in camera-type eye |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SOX1 |
Protein name | Transcription factor SOX-1 |
Synonyms | |
Description | FUNCTION: Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). . |
Accessions | ENST00000330949.3 O00570 |