Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 23 studies | 34% ± 15% | |
| pericyte | 23 studies | 28% ± 13% | |
| oligodendrocyte | 16 studies | 56% ± 18% | |
| goblet cell | 12 studies | 51% ± 20% | |
| glutamatergic neuron | 9 studies | 44% ± 26% | |
| retinal cone cell | 7 studies | 45% ± 8% | |
| respiratory goblet cell | 6 studies | 33% ± 12% | |
| epithelial cell | 6 studies | 46% ± 5% | |
| capillary endothelial cell | 6 studies | 29% ± 12% | |
| basal cell | 6 studies | 34% ± 12% | |
| GABAergic neuron | 6 studies | 42% ± 21% | |
| oligodendrocyte precursor cell | 6 studies | 26% ± 9% | |
| club cell | 5 studies | 29% ± 6% | |
| ionocyte | 5 studies | 37% ± 14% | |
| intestinal crypt stem cell | 5 studies | 62% ± 15% | |
| transit amplifying cell | 5 studies | 49% ± 20% | |
| interneuron | 5 studies | 37% ± 19% | |
| retinal rod cell | 5 studies | 31% ± 11% | |
| fibroblast | 5 studies | 19% ± 2% | |
| mucus secreting cell | 5 studies | 60% ± 21% | |
| astrocyte | 5 studies | 27% ± 12% | |
| duct epithelial cell | 4 studies | 42% ± 26% | |
| neuron | 4 studies | 32% ± 16% | |
| progenitor cell | 4 studies | 30% ± 12% | |
| microglial cell | 4 studies | 18% ± 1% | |
| smooth muscle cell | 4 studies | 32% ± 19% | |
| retina horizontal cell | 4 studies | 27% ± 14% | |
| retinal pigment epithelial cell | 4 studies | 29% ± 8% | |
| luminal cell of prostate epithelium | 4 studies | 29% ± 10% | |
| secretory cell | 3 studies | 35% ± 14% | |
| cholangiocyte | 3 studies | 37% ± 17% | |
| endothelial cell of artery | 3 studies | 20% ± 3% | |
| interstitial cell of Cajal | 3 studies | 32% ± 17% | |
| retinal bipolar neuron | 3 studies | 23% ± 7% | |
| ciliated cell | 3 studies | 36% ± 15% | |
| OFF-bipolar cell | 3 studies | 49% ± 12% | |
| ON-bipolar cell | 3 studies | 31% ± 13% | |
| type II pneumocyte | 3 studies | 21% ± 4% | |
| pancreatic ductal cell | 3 studies | 40% ± 19% | |
| brush cell | 3 studies | 20% ± 2% | |
| granule cell | 3 studies | 27% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 4949.01 | 966 / 966 | 97% | 145.40 | 513 / 527 |
| stomach | 100% | 5029.25 | 359 / 359 | 96% | 112.04 | 275 / 286 |
| prostate | 100% | 3555.04 | 244 / 245 | 96% | 60.78 | 481 / 502 |
| breast | 99% | 3105.88 | 456 / 459 | 87% | 59.14 | 976 / 1118 |
| brain | 99% | 3322.21 | 2626 / 2642 | 78% | 15.24 | 549 / 705 |
| thymus | 100% | 1721.51 | 650 / 653 | 71% | 14.89 | 432 / 605 |
| pancreas | 80% | 1025.70 | 261 / 328 | 87% | 34.45 | 154 / 178 |
| esophagus | 87% | 3525.58 | 1260 / 1445 | 77% | 47.35 | 140 / 183 |
| lung | 97% | 1740.24 | 561 / 578 | 65% | 24.16 | 749 / 1155 |
| skin | 100% | 6897.30 | 1804 / 1809 | 53% | 10.64 | 250 / 472 |
| bladder | 95% | 1442.71 | 20 / 21 | 56% | 53.52 | 280 / 504 |
| uterus | 98% | 1542.05 | 166 / 170 | 38% | 10.32 | 176 / 459 |
| adrenal gland | 100% | 3515.95 | 257 / 258 | 27% | 5.87 | 61 / 230 |
| ovary | 99% | 1898.94 | 178 / 180 | 22% | 3.28 | 96 / 430 |
| kidney | 64% | 684.11 | 57 / 89 | 36% | 6.88 | 321 / 901 |
| adipose | 99% | 1989.85 | 1193 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 94% | 1608.11 | 755 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 85% | 1017.31 | 1136 / 1335 | 0% | 0 | 0 / 0 |
| heart | 81% | 965.37 | 699 / 861 | 0% | 0 | 0 / 0 |
| spleen | 75% | 703.37 | 180 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 44% | 7.33 | 20 / 45 |
| liver | 16% | 143.07 | 36 / 226 | 25% | 13.06 | 100 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 21% | 3.02 | 6 / 29 |
| peripheral blood | 19% | 602.86 | 179 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.14 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0045795 | Biological process | positive regulation of cell volume |
| GO_0055064 | Biological process | chloride ion homeostasis |
| GO_0035865 | Biological process | cellular response to potassium ion |
| GO_0098659 | Biological process | inorganic cation import across plasma membrane |
| GO_0150104 | Biological process | transport across blood-brain barrier |
| GO_0072488 | Biological process | ammonium transmembrane transport |
| GO_0055078 | Biological process | sodium ion homeostasis |
| GO_0006811 | Biological process | monoatomic ion transport |
| GO_0006884 | Biological process | cell volume homeostasis |
| GO_0006883 | Biological process | intracellular sodium ion homeostasis |
| GO_0055075 | Biological process | potassium ion homeostasis |
| GO_1904450 | Biological process | positive regulation of aspartate secretion |
| GO_0006972 | Biological process | hyperosmotic response |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0030321 | Biological process | transepithelial chloride transport |
| GO_0098719 | Biological process | sodium ion import across plasma membrane |
| GO_0098658 | Biological process | inorganic anion import across plasma membrane |
| GO_0030644 | Biological process | intracellular chloride ion homeostasis |
| GO_0035633 | Biological process | maintenance of blood-brain barrier |
| GO_0150003 | Biological process | regulation of spontaneous synaptic transmission |
| GO_1990869 | Biological process | cellular response to chemokine |
| GO_1904464 | Biological process | regulation of matrix metallopeptidase secretion |
| GO_0007214 | Biological process | gamma-aminobutyric acid signaling pathway |
| GO_0010818 | Biological process | T cell chemotaxis |
| GO_0030007 | Biological process | intracellular potassium ion homeostasis |
| GO_0061044 | Biological process | negative regulation of vascular wound healing |
| GO_0070634 | Biological process | transepithelial ammonium transport |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_1990573 | Biological process | potassium ion import across plasma membrane |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_1903561 | Cellular component | extracellular vesicle |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0009925 | Cellular component | basal plasma membrane |
| GO_0043005 | Cellular component | neuron projection |
| GO_0044298 | Cellular component | cell body membrane |
| GO_0071944 | Cellular component | cell periphery |
| GO_0016328 | Cellular component | lateral plasma membrane |
| GO_0031253 | Cellular component | cell projection membrane |
| GO_0042995 | Cellular component | cell projection |
| GO_0044297 | Cellular component | cell body |
| GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0051879 | Molecular function | Hsp90 protein binding |
| GO_0008511 | Molecular function | sodium:potassium:chloride symporter activity |
| GO_0015079 | Molecular function | potassium ion transmembrane transporter activity |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0008519 | Molecular function | ammonium channel activity |
| GO_0051087 | Molecular function | protein-folding chaperone binding |
| GO_0015377 | Molecular function | chloride:monoatomic cation symporter activity |
| GO_0046873 | Molecular function | metal ion transmembrane transporter activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SLC12A2 |
| Protein name | SLC12A2 protein Solute carrier family 12 (Sodium/potassium/chloride transporters), member 2, isoform CRA_a (Solute carrier family 12 member 2) Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Bumetanide-sensitive Na-K-Cl cotransporter (Solute carrier family 12 (Sodium/potassium/chloride transporters), member 2, isoform CRA_b) |
| Synonyms | NKCC1 hCG_27034 |
| Description | FUNCTION: Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane . Plays a vital role in the regulation of ionic balance and cell volume . . |
| Accessions | B7ZM24 Q53ZR1 ENST00000343225.4 [P55011-3] ENST00000509205.5 G3XAL9 ENST00000628403.2 ENST00000262461.7 [P55011-1] P55011 |