SEC24B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090178Biological processregulation of establishment of planar polarity involved in neural tube closure
GO_0021747Biological processcochlear nucleus development
GO_0003151Biological processoutflow tract morphogenesis
GO_0006886Biological processintracellular protein transport
GO_0060088Biological processauditory receptor cell stereocilium organization
GO_0060463Biological processlung lobe morphogenesis
GO_0035909Biological processaorta morphogenesis
GO_1901301Biological processregulation of cargo loading into COPII-coated vesicle
GO_0001843Biological processneural tube closure
GO_0061156Biological processpulmonary artery morphogenesis
GO_0060982Biological processcoronary artery morphogenesis
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0090110Biological processCOPII-coated vesicle cargo loading
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0030127Cellular componentCOPII vesicle coat
GO_0070971Cellular componentendoplasmic reticulum exit site
GO_0005829Cellular componentcytosol
GO_0012507Cellular componentER to Golgi transport vesicle membrane
GO_0000149Molecular functionSNARE binding
GO_0008270Molecular functionzinc ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSEC24B
Protein nameProtein transport protein Sec24B (SEC24-related protein B)
Synonyms
DescriptionFUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex . Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes . .

AccessionsENST00000399100.6 [O95487-2]
ENST00000265175.5 [O95487-1]
ENST00000504968.6 [O95487-3]
O95487