Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 20 studies | 24% ± 9% | |
endothelial cell | 18 studies | 26% ± 9% | |
smooth muscle cell | 12 studies | 19% ± 2% | |
adipocyte | 10 studies | 27% ± 7% | |
pericyte | 8 studies | 22% ± 6% | |
connective tissue cell | 7 studies | 26% ± 9% | |
astrocyte | 7 studies | 29% ± 12% | |
epithelial cell | 6 studies | 33% ± 13% | |
GABAergic neuron | 6 studies | 38% ± 19% | |
oligodendrocyte | 6 studies | 24% ± 7% | |
glutamatergic neuron | 5 studies | 48% ± 23% | |
microglial cell | 5 studies | 22% ± 5% | |
myofibroblast cell | 5 studies | 19% ± 4% | |
hepatocyte | 5 studies | 36% ± 20% | |
macrophage | 5 studies | 24% ± 7% | |
type I pneumocyte | 5 studies | 20% ± 5% | |
neuron | 4 studies | 29% ± 8% | |
enterocyte | 4 studies | 20% ± 4% | |
oligodendrocyte precursor cell | 4 studies | 30% ± 8% | |
endothelial cell of lymphatic vessel | 4 studies | 19% ± 4% | |
interneuron | 4 studies | 41% ± 21% | |
CD4-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
classical monocyte | 3 studies | 16% ± 1% | |
hematopoietic precursor cell | 3 studies | 19% ± 3% | |
plasma cell | 3 studies | 26% ± 5% | |
retinal cone cell | 3 studies | 25% ± 5% | |
retinal rod cell | 3 studies | 17% ± 2% | |
cardiac muscle cell | 3 studies | 18% ± 3% | |
mesothelial cell | 3 studies | 17% ± 1% | |
ciliated cell | 3 studies | 15% ± 0% | |
lymphocyte | 3 studies | 22% ± 6% | |
rod bipolar cell | 3 studies | 16% ± 0% | |
dendritic cell | 3 studies | 22% ± 6% | |
alveolar macrophage | 3 studies | 23% ± 6% | |
mast cell | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 5689.69 | 966 / 966 | 100% | 26.72 | 526 / 527 |
lung | 99% | 3226.12 | 575 / 578 | 100% | 28.68 | 1151 / 1155 |
esophagus | 99% | 5335.68 | 1432 / 1445 | 100% | 35.31 | 183 / 183 |
breast | 100% | 4338.10 | 459 / 459 | 98% | 26.30 | 1099 / 1118 |
ovary | 100% | 4088.12 | 180 / 180 | 98% | 16.00 | 420 / 430 |
thymus | 100% | 2819.35 | 651 / 653 | 98% | 20.14 | 590 / 605 |
bladder | 100% | 5447.38 | 21 / 21 | 97% | 22.71 | 488 / 504 |
liver | 100% | 3947.21 | 226 / 226 | 97% | 21.08 | 393 / 406 |
uterus | 100% | 5322.78 | 170 / 170 | 97% | 24.33 | 443 / 459 |
adrenal gland | 100% | 4780.05 | 258 / 258 | 94% | 19.50 | 217 / 230 |
prostate | 99% | 3409.84 | 243 / 245 | 94% | 15.01 | 472 / 502 |
skin | 98% | 6066.53 | 1780 / 1809 | 95% | 26.54 | 447 / 472 |
brain | 91% | 2222.35 | 2392 / 2642 | 100% | 19.53 | 702 / 705 |
kidney | 93% | 1815.76 | 83 / 89 | 94% | 22.84 | 846 / 901 |
stomach | 88% | 2826.71 | 315 / 359 | 99% | 28.32 | 283 / 286 |
pancreas | 45% | 519.05 | 148 / 328 | 98% | 25.59 | 174 / 178 |
adipose | 100% | 5184.43 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 8470.53 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 4219.11 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.02 | 1 / 1 |
spleen | 98% | 1975.01 | 237 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 17.74 | 43 / 45 |
heart | 93% | 3484.73 | 803 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 90% | 13.16 | 26 / 29 |
eye | 0% | 0 | 0 / 0 | 59% | 6.42 | 47 / 80 |
peripheral blood | 51% | 1411.33 | 471 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006886 | Biological process | intracellular protein transport |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0090110 | Biological process | COPII-coated vesicle cargo loading |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0012507 | Cellular component | ER to Golgi transport vesicle membrane |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005829 | Cellular component | cytosol |
GO_0030127 | Cellular component | COPII vesicle coat |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0070971 | Cellular component | endoplasmic reticulum exit site |
GO_0005515 | Molecular function | protein binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0005096 | Molecular function | GTPase activator activity |
Gene name | SEC23A |
Protein name | Protein transport protein SEC23 Alternative protein SEC23A Protein transport protein Sec23A (hSec23A) (SEC23-related protein A) SEC23 homolog A, COPII coat complex component |
Synonyms | |
Description | FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane (By similarity). . FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. . FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. . FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. . FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. . FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. . FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. . FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. . |
Accessions | G3V5K1 ENST00000307712.11 [Q15436-1] ENST00000557437.1 ENST00000537403.5 [Q15436-2] ENST00000548032.6 ENST00000555425.5 Q15436 F5H365 ENST00000545328.6 ENST00000555017.5 L8ECD0 G3V4Q2 G3V2R6 ENST00000557280.5 G3V1W4 ENST00000553970.1 ENST00000625395.1 G3V3G5 G3V5X8 ENST00000556092.5 G3V4V1 |