Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 7 studies | 20% ± 3% | |
endothelial cell | 5 studies | 24% ± 10% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 18% ± 2% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 20% ± 2% | |
CD4-positive, alpha-beta T cell | 4 studies | 17% ± 2% | |
mature NK T cell | 4 studies | 17% ± 2% | |
CD8-positive, alpha-beta T cell | 4 studies | 22% ± 4% | |
epithelial cell | 4 studies | 35% ± 12% | |
ciliated cell | 4 studies | 26% ± 6% | |
pancreatic A cell | 3 studies | 25% ± 6% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 3 studies | 20% ± 1% | |
classical monocyte | 3 studies | 25% ± 7% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 20% ± 3% | |
non-classical monocyte | 3 studies | 22% ± 6% | |
mucosal invariant T cell | 3 studies | 18% ± 2% | |
gamma-delta T cell | 3 studies | 23% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 2100.60 | 258 / 258 | 100% | 20.38 | 230 / 230 |
esophagus | 100% | 1489.36 | 1445 / 1445 | 100% | 20.48 | 183 / 183 |
liver | 100% | 1286.96 | 226 / 226 | 100% | 17.23 | 406 / 406 |
ovary | 100% | 1466.99 | 180 / 180 | 100% | 22.03 | 430 / 430 |
prostate | 100% | 1684.54 | 245 / 245 | 100% | 22.64 | 502 / 502 |
skin | 100% | 1575.28 | 1809 / 1809 | 100% | 17.90 | 472 / 472 |
stomach | 100% | 1349.39 | 359 / 359 | 100% | 18.18 | 286 / 286 |
thymus | 100% | 1743.24 | 653 / 653 | 100% | 21.46 | 605 / 605 |
uterus | 100% | 1569.95 | 170 / 170 | 100% | 21.74 | 459 / 459 |
lung | 100% | 1425.32 | 577 / 578 | 100% | 17.18 | 1155 / 1155 |
intestine | 100% | 1579.51 | 966 / 966 | 100% | 18.49 | 526 / 527 |
brain | 100% | 1157.24 | 2637 / 2642 | 100% | 18.03 | 704 / 705 |
bladder | 100% | 1515.95 | 21 / 21 | 100% | 22.23 | 502 / 504 |
kidney | 100% | 1525.30 | 89 / 89 | 100% | 14.08 | 897 / 901 |
breast | 100% | 1800.67 | 459 / 459 | 99% | 19.80 | 1112 / 1118 |
pancreas | 100% | 769.95 | 327 / 328 | 99% | 18.34 | 177 / 178 |
adipose | 100% | 1742.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1415.86 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 17.93 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 42.01 | 29 / 29 |
muscle | 100% | 1673.94 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1970.90 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 18.24 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 29.83 | 1 / 1 |
heart | 100% | 1458.98 | 858 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 1812.19 | 920 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0034553 | Biological process | mitochondrial respiratory chain complex II assembly |
GO_0006121 | Biological process | mitochondrial electron transport, succinate to ubiquinone |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0010719 | Biological process | negative regulation of epithelial to mesenchymal transition |
GO_0006099 | Biological process | tricarboxylic acid cycle |
GO_0018293 | Biological process | protein-FAD linkage |
GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
GO_0005730 | Cellular component | nucleolus |
GO_0005829 | Cellular component | cytosol |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005739 | Cellular component | mitochondrion |
GO_0005515 | Molecular function | protein binding |
Gene name | SDHAF2 |
Protein name | Succinate dehydrogenase complex assembly factor 2 Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (SDHAF2) |
Synonyms | PGL2 C11orf79 SDH5 |
Description | FUNCTION: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. . FUNCTION: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. . |
Accessions | ENST00000537782.5 M0QY91 Q9NX18 ENST00000301761.7 F5H8E2 M0R060 ENST00000536250.1 ENST00000543265.1 F5H4T4 F5GYJ5 M0QYN2 F8W679 ENST00000543044.2 ENST00000542794.5 ENST00000359614.9 ENST00000534878.5 ENST00000542074.1 |