Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 45 studies | 45% ± 21% | |
endothelial cell of lymphatic vessel | 20 studies | 41% ± 22% | |
astrocyte | 19 studies | 62% ± 20% | |
pericyte | 19 studies | 31% ± 11% | |
fibroblast | 16 studies | 33% ± 14% | |
oligodendrocyte | 15 studies | 52% ± 18% | |
oligodendrocyte precursor cell | 15 studies | 42% ± 20% | |
capillary endothelial cell | 15 studies | 37% ± 19% | |
macrophage | 14 studies | 26% ± 13% | |
endothelial cell of artery | 13 studies | 31% ± 16% | |
endothelial cell of vascular tree | 12 studies | 38% ± 21% | |
smooth muscle cell | 11 studies | 38% ± 22% | |
vein endothelial cell | 10 studies | 47% ± 24% | |
GABAergic neuron | 7 studies | 39% ± 16% | |
epithelial cell | 7 studies | 34% ± 22% | |
glutamatergic neuron | 6 studies | 47% ± 19% | |
adipocyte | 6 studies | 27% ± 9% | |
Mueller cell | 6 studies | 53% ± 19% | |
basal cell | 6 studies | 31% ± 20% | |
glial cell | 5 studies | 31% ± 11% | |
interneuron | 5 studies | 25% ± 9% | |
microglial cell | 5 studies | 42% ± 26% | |
mesothelial cell | 5 studies | 35% ± 12% | |
monocyte | 5 studies | 23% ± 6% | |
type I pneumocyte | 5 studies | 28% ± 6% | |
type II pneumocyte | 5 studies | 24% ± 7% | |
squamous epithelial cell | 4 studies | 48% ± 22% | |
retinal pigment epithelial cell | 4 studies | 45% ± 20% | |
myeloid cell | 4 studies | 28% ± 8% | |
endothelial cell of sinusoid | 3 studies | 44% ± 15% | |
glomerular endothelial cell | 3 studies | 31% ± 3% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 46% ± 8% | |
GABAergic interneuron | 3 studies | 32% ± 20% | |
neuron | 3 studies | 50% ± 7% | |
endocardial cell | 3 studies | 41% ± 17% | |
mononuclear phagocyte | 3 studies | 27% ± 9% | |
ciliated cell | 3 studies | 33% ± 9% | |
rod bipolar cell | 3 studies | 61% ± 29% | |
abnormal cell | 3 studies | 23% ± 6% | |
connective tissue cell | 3 studies | 26% ± 10% | |
ependymal cell | 3 studies | 59% ± 13% | |
alveolar macrophage | 3 studies | 32% ± 8% | |
club cell | 3 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 100% | 9537.50 | 1809 / 1809 | 98% | 26.22 | 462 / 472 |
breast | 100% | 15017.42 | 459 / 459 | 94% | 22.56 | 1050 / 1118 |
esophagus | 100% | 9096.86 | 1444 / 1445 | 93% | 14.61 | 170 / 183 |
prostate | 93% | 3226.53 | 229 / 245 | 99% | 22.74 | 497 / 502 |
thymus | 100% | 13224.74 | 653 / 653 | 92% | 30.95 | 557 / 605 |
brain | 93% | 6361.82 | 2447 / 2642 | 99% | 41.24 | 701 / 705 |
lung | 100% | 9072.31 | 577 / 578 | 88% | 9.71 | 1020 / 1155 |
uterus | 100% | 4769.07 | 170 / 170 | 86% | 10.93 | 396 / 459 |
kidney | 90% | 3755.34 | 80 / 89 | 94% | 21.99 | 847 / 901 |
bladder | 100% | 4392.71 | 21 / 21 | 83% | 9.95 | 420 / 504 |
intestine | 94% | 4819.85 | 907 / 966 | 72% | 6.47 | 380 / 527 |
stomach | 62% | 2242.98 | 223 / 359 | 77% | 8.03 | 220 / 286 |
ovary | 54% | 1537.07 | 97 / 180 | 78% | 7.80 | 337 / 430 |
pancreas | 13% | 278.41 | 44 / 328 | 87% | 9.03 | 155 / 178 |
adipose | 100% | 19788.46 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 9444.46 | 1335 / 1335 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.30 | 1 / 1 |
heart | 95% | 3387.59 | 814 / 861 | 0% | 0 | 0 / 0 |
muscle | 90% | 3107.15 | 719 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 88% | 11.38 | 70 / 80 |
spleen | 83% | 2480.47 | 199 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 17% | 356.10 | 43 / 258 | 62% | 6.22 | 142 / 230 |
tonsil | 0% | 0 | 0 / 0 | 76% | 11.82 | 34 / 45 |
liver | 6% | 122.80 | 14 / 226 | 43% | 3.04 | 176 / 406 |
lymph node | 0% | 0 | 0 / 0 | 34% | 2.36 | 10 / 29 |
peripheral blood | 2% | 36.86 | 14 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0043507 | Biological process | positive regulation of JUN kinase activity |
GO_1901224 | Biological process | positive regulation of non-canonical NF-kappaB signal transduction |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0031666 | Biological process | positive regulation of lipopolysaccharide-mediated signaling pathway |
GO_0010595 | Biological process | positive regulation of endothelial cell migration |
GO_1900044 | Biological process | regulation of protein K63-linked ubiquitination |
GO_1900745 | Biological process | positive regulation of p38MAPK cascade |
GO_1902498 | Biological process | regulation of protein autoubiquitination |
GO_0010632 | Biological process | regulation of epithelial cell migration |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0060090 | Molecular function | molecular adaptor activity |
GO_0031435 | Molecular function | mitogen-activated protein kinase kinase kinase binding |
GO_0001965 | Molecular function | G-protein alpha-subunit binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SASH1 |
Protein name | SASH1 protein SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat-containing protein) Alternative protein SASH1 SAM and SH3 domain containing 1 |
Synonyms | PEPE1 KIAA0790 |
Description | FUNCTION: Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation . Regulates TRAF6 and MAP3K7 ubiquitination . Involved in the regulation of cell mobility . Regulates lipolysaccharide (LPS)-induced endothelial cell migration . Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis . . |
Accessions | ENST00000636279.1 ENST00000637469.1 Q6P4R9 ENST00000367467.8 L8EAS6 O94885 A0A1B0GVF9 ENST00000637729.1 A0A1B0GVI0 A0A1B0GWB9 |