SAP30 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030336Biological processnegative regulation of cell migration
GO_0052472Biological processmodulation by host of symbiont transcription
GO_1902455Biological processnegative regulation of stem cell population maintenance
GO_1902459Biological processpositive regulation of stem cell population maintenance
GO_0035914Biological processskeletal muscle cell differentiation
GO_0030512Biological processnegative regulation of transforming growth factor beta receptor signaling pathway
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0000118Cellular componenthistone deacetylase complex
GO_0070822Cellular componentSin3-type complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0005515Molecular functionprotein binding
GO_0003712Molecular functiontranscription coregulator activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameSAP30
Protein nameHistone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30)
Synonyms
DescriptionFUNCTION: Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. .; FUNCTION: (Microbial infection) Involved in transcriptional repression of HHV-1 genes TK and gC. .

AccessionsENST00000296504.4
O75446