Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 11 studies | 39% ± 17% | |
ciliated cell | 8 studies | 29% ± 16% | |
epithelial cell | 5 studies | 39% ± 14% | |
macrophage | 5 studies | 18% ± 2% | |
fibroblast | 4 studies | 18% ± 3% | |
endothelial cell of lymphatic vessel | 3 studies | 20% ± 6% | |
classical monocyte | 3 studies | 22% ± 6% | |
glomerular endothelial cell | 3 studies | 21% ± 3% | |
endothelial cell | 3 studies | 23% ± 6% | |
oligodendrocyte precursor cell | 3 studies | 32% ± 6% | |
astrocyte | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 28% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4020.79 | 244 / 245 | 100% | 135.72 | 501 / 502 |
liver | 100% | 2731.91 | 226 / 226 | 99% | 63.14 | 402 / 406 |
ovary | 100% | 5408.09 | 180 / 180 | 97% | 46.00 | 415 / 430 |
thymus | 100% | 3223.89 | 651 / 653 | 97% | 85.28 | 585 / 605 |
brain | 94% | 4297.43 | 2480 / 2642 | 100% | 105.96 | 703 / 705 |
stomach | 100% | 3913.61 | 359 / 359 | 92% | 32.95 | 264 / 286 |
intestine | 99% | 3136.50 | 953 / 966 | 88% | 28.43 | 462 / 527 |
pancreas | 88% | 1454.91 | 290 / 328 | 95% | 41.48 | 169 / 178 |
bladder | 100% | 4011.29 | 21 / 21 | 81% | 51.32 | 410 / 504 |
lung | 100% | 3058.97 | 577 / 578 | 76% | 34.67 | 883 / 1155 |
breast | 100% | 3730.60 | 459 / 459 | 68% | 21.95 | 763 / 1118 |
kidney | 83% | 1202.26 | 74 / 89 | 83% | 34.94 | 744 / 901 |
adrenal gland | 99% | 2210.19 | 256 / 258 | 66% | 37.30 | 151 / 230 |
uterus | 99% | 2623.01 | 168 / 170 | 57% | 29.44 | 261 / 459 |
esophagus | 78% | 2187.76 | 1130 / 1445 | 53% | 18.06 | 97 / 183 |
spleen | 100% | 3309.41 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 280.86 | 1 / 1 |
adipose | 100% | 4255.94 | 1202 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 3518.29 | 1328 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 4490.93 | 793 / 803 | 0% | 0 | 0 / 0 |
skin | 61% | 865.94 | 1108 / 1809 | 19% | 6.20 | 90 / 472 |
heart | 57% | 1061.89 | 488 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 30% | 373.89 | 283 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 21% | 4.08 | 6 / 29 |
tonsil | 0% | 0 | 0 / 0 | 11% | 2.63 | 5 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006897 | Biological process | endocytosis |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0007163 | Biological process | establishment or maintenance of cell polarity |
GO_0007010 | Biological process | cytoskeleton organization |
GO_0016601 | Biological process | Rac protein signal transduction |
GO_0007015 | Biological process | actin filament organization |
GO_0032488 | Biological process | Cdc42 protein signal transduction |
GO_0008360 | Biological process | regulation of cell shape |
GO_1903955 | Biological process | positive regulation of protein targeting to mitochondrion |
GO_0000082 | Biological process | G1/S transition of mitotic cell cycle |
GO_0005886 | Cellular component | plasma membrane |
GO_0002102 | Cellular component | podosome |
GO_0005925 | Cellular component | focal adhesion |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005829 | Cellular component | cytosol |
GO_0042995 | Cellular component | cell projection |
GO_0010008 | Cellular component | endosome membrane |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005525 | Molecular function | GTP binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | RHOU |
Protein name | Rho-related GTP-binding protein RhoU (CDC42-like GTPase 1) (GTP-binding protein-like 1) (Rho GTPase-like protein ARHU) (Ryu GTPase) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1) |
Synonyms | G28K ARHU WRCH1 CDC42L1 SB128 |
Description | FUNCTION: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. . |
Accessions | ENST00000366691.4 [Q7L0Q8-1] ENST00000646945.2 [Q7L0Q8-1] Q7L0Q8 |