Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 20 studies | 31% ± 13% | |
| fibroblast | 18 studies | 29% ± 12% | |
| pericyte | 18 studies | 29% ± 12% | |
| smooth muscle cell | 18 studies | 24% ± 9% | |
| classical monocyte | 14 studies | 27% ± 14% | |
| microglial cell | 10 studies | 35% ± 12% | |
| astrocyte | 10 studies | 29% ± 12% | |
| dendritic cell | 9 studies | 25% ± 13% | |
| non-classical monocyte | 9 studies | 32% ± 17% | |
| monocyte | 8 studies | 30% ± 7% | |
| endothelial cell | 7 studies | 29% ± 9% | |
| myeloid cell | 7 studies | 30% ± 8% | |
| adipocyte | 7 studies | 26% ± 5% | |
| B cell | 6 studies | 25% ± 3% | |
| alveolar macrophage | 5 studies | 27% ± 10% | |
| mononuclear phagocyte | 5 studies | 27% ± 7% | |
| retina horizontal cell | 5 studies | 27% ± 10% | |
| cardiac muscle cell | 5 studies | 35% ± 4% | |
| oligodendrocyte | 5 studies | 25% ± 8% | |
| connective tissue cell | 5 studies | 25% ± 10% | |
| natural killer cell | 4 studies | 18% ± 2% | |
| conventional dendritic cell | 4 studies | 28% ± 12% | |
| retinal ganglion cell | 4 studies | 44% ± 19% | |
| epithelial cell | 4 studies | 27% ± 4% | |
| GABAergic neuron | 4 studies | 33% ± 11% | |
| oligodendrocyte precursor cell | 4 studies | 33% ± 9% | |
| CD16-positive, CD56-dim natural killer cell, human | 3 studies | 17% ± 1% | |
| plasmablast | 3 studies | 29% ± 9% | |
| basal cell | 3 studies | 21% ± 2% | |
| retinal pigment epithelial cell | 3 studies | 43% ± 20% | |
| mesothelial cell | 3 studies | 16% ± 0% | |
| lymphocyte | 3 studies | 23% ± 5% | |
| memory B cell | 3 studies | 20% ± 5% | |
| muscle cell | 3 studies | 33% ± 12% | |
| glutamatergic neuron | 3 studies | 36% ± 17% | |
| leukocyte | 3 studies | 23% ± 7% | |
| myofibroblast cell | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 3355.43 | 89 / 89 | 100% | 33.73 | 900 / 901 |
| breast | 100% | 6522.46 | 459 / 459 | 100% | 27.87 | 1116 / 1118 |
| ovary | 100% | 3876.09 | 180 / 180 | 100% | 26.22 | 429 / 430 |
| lung | 100% | 5545.52 | 577 / 578 | 100% | 27.90 | 1154 / 1155 |
| prostate | 100% | 5425.42 | 244 / 245 | 100% | 27.74 | 502 / 502 |
| thymus | 100% | 4262.53 | 652 / 653 | 100% | 31.60 | 602 / 605 |
| skin | 99% | 3404.22 | 1792 / 1809 | 100% | 74.21 | 471 / 472 |
| bladder | 100% | 6292.19 | 21 / 21 | 99% | 25.41 | 497 / 504 |
| adrenal gland | 100% | 3383.02 | 258 / 258 | 98% | 25.40 | 226 / 230 |
| uterus | 100% | 5506.24 | 170 / 170 | 97% | 20.89 | 444 / 459 |
| brain | 96% | 3618.26 | 2544 / 2642 | 100% | 33.12 | 705 / 705 |
| intestine | 99% | 5063.32 | 955 / 966 | 94% | 13.96 | 498 / 527 |
| esophagus | 93% | 4838.72 | 1345 / 1445 | 99% | 20.08 | 181 / 183 |
| stomach | 88% | 2701.71 | 317 / 359 | 97% | 16.45 | 276 / 286 |
| pancreas | 84% | 1516.00 | 275 / 328 | 98% | 23.78 | 175 / 178 |
| liver | 46% | 866.64 | 105 / 226 | 73% | 9.90 | 296 / 406 |
| blood vessel | 100% | 8334.27 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 64.18 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 28.96 | 29 / 29 |
| muscle | 100% | 8537.35 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4266.49 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 23.13 | 1 / 1 |
| adipose | 100% | 9088.44 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| heart | 99% | 9698.43 | 852 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 12.65 | 43 / 45 |
| peripheral blood | 75% | 2036.61 | 693 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046326 | Biological process | positive regulation of glucose import |
| GO_0006897 | Biological process | endocytosis |
| GO_0032869 | Biological process | cellular response to insulin stimulus |
| GO_0046039 | Biological process | GTP metabolic process |
| GO_0007165 | Biological process | signal transduction |
| GO_0007163 | Biological process | establishment or maintenance of cell polarity |
| GO_0051491 | Biological process | positive regulation of filopodium assembly |
| GO_0008286 | Biological process | insulin receptor signaling pathway |
| GO_0007264 | Biological process | small GTPase-mediated signal transduction |
| GO_0007015 | Biological process | actin filament organization |
| GO_0008360 | Biological process | regulation of cell shape |
| GO_1903077 | Biological process | negative regulation of protein localization to plasma membrane |
| GO_0030866 | Biological process | cortical actin cytoskeleton organization |
| GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0045121 | Cellular component | membrane raft |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005884 | Cellular component | actin filament |
| GO_0030660 | Cellular component | Golgi-associated vesicle membrane |
| GO_0032427 | Molecular function | GBD domain binding |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0005525 | Molecular function | GTP binding |
| GO_0005522 | Molecular function | profilin binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | RHOQ |
| Protein name | Ras homolog family member Q Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A) Epididymis secretory protein Li 42 (Ras homolog gene family, member Q, isoform CRA_d) |
| Synonyms | RASL7A ARHQ hCG_1995863 HEL-S-42 TC10 |
| Description | FUNCTION: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. . |
| Accessions | ENST00000482449.2 ENST00000432183.5 P17081 ENST00000238738.9 H0YB40 H0YB93 E5RFZ3 F8WET9 ENST00000489471.5 ENST00000473428.1 V9HWD0 |