RHOQ report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046326Biological processpositive regulation of glucose import
GO_0006897Biological processendocytosis
GO_0032869Biological processcellular response to insulin stimulus
GO_0046039Biological processGTP metabolic process
GO_0007165Biological processsignal transduction
GO_0007163Biological processestablishment or maintenance of cell polarity
GO_0051491Biological processpositive regulation of filopodium assembly
GO_0008286Biological processinsulin receptor signaling pathway
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0007015Biological processactin filament organization
GO_0008360Biological processregulation of cell shape
GO_1903077Biological processnegative regulation of protein localization to plasma membrane
GO_0030866Biological processcortical actin cytoskeleton organization
GO_0032956Biological processregulation of actin cytoskeleton organization
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005886Cellular componentplasma membrane
GO_0045121Cellular componentmembrane raft
GO_0070062Cellular componentextracellular exosome
GO_0005884Cellular componentactin filament
GO_0030660Cellular componentGolgi-associated vesicle membrane
GO_0032427Molecular functionGBD domain binding
GO_0019901Molecular functionprotein kinase binding
GO_0005525Molecular functionGTP binding
GO_0005522Molecular functionprofilin binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRHOQ
Protein nameRas homolog family member Q
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Epididymis secretory protein Li 42 (Ras homolog gene family, member Q, isoform CRA_d)
SynonymsRASL7A
ARHQ
hCG_1995863
HEL-S-42
TC10
DescriptionFUNCTION: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. .

AccessionsENST00000482449.2
ENST00000432183.5
P17081
ENST00000238738.9
H0YB40
H0YB93
E5RFZ3
F8WET9
ENST00000489471.5
ENST00000473428.1
V9HWD0