RHOBTB3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008584Biological processmale gonad development
GO_0042147Biological processretrograde transport, endosome to Golgi
GO_0030162Biological processregulation of proteolysis
GO_0043161Biological processproteasome-mediated ubiquitin-dependent protein catabolic process
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRHOBTB3
Protein nameRho-related BTB domain-containing protein 3 (EC 3.6.1.-)
Rho related BTB domain containing 3
SynonymsKIAA0878
DescriptionFUNCTION: Rab9-regulated ATPase required for endosome to Golgi transport. Involved in transport vesicle docking at the Golgi complex, possibly by participating in release M6PRBP1/TIP47 from vesicles to permit their efficient docking and fusion at the Golgi. Specifically binds Rab9, but not other Rab proteins. Has low intrinsic ATPase activity due to autoinhibition, which is relieved by Rab9. .

AccessionsENST00000510623.1
ENST00000506959.5
ENST00000379982.8
ENST00000510313.1
D6R935
H0Y9P6
ENST00000503737.1
H0YA85
ENST00000504179.5
O94955
H0Y8R9
D6RG10
ENST00000506817.1
H0Y9W9
D6RC79
ENST00000502541.1
H0Y9R7
ENST00000513091.1
H0Y9A8
ENST00000514198.1