RFX5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RFX5 at tissue level.

III. Associated gene sets

GO_0045348Biological processpositive regulation of MHC class II biosynthetic process
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding

IV. Literature review

[source]
Gene nameRFX5
Protein nameDNA-binding protein RFX5 (Regulatory factor X 5)
Regulatory factor X5
Synonyms
DescriptionFUNCTION: Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters.

AccessionsENST00000450506.5
ENST00000421986.5
F8WDU3
P48382
F8WFE4
A0A0A0MSM9
ENST00000452671.7 [P48382-1]
ENST00000290524.8 [P48382-1]
A0A0A0MT34
ENST00000458484.5
A0A0A0MSQ2
ENST00000412774.5
F8W689
ENST00000392746.7
H0Y4B4
ENST00000422595.5
F6R6G4
ENST00000452456.1
F6S3S0
ENST00000430227.5
ENST00000436271.5
ENST00000436637.5
ENST00000437327.5
ENST00000444392.5
F6X9D6
F2Z2G0
ENST00000368870.6 [P48382-1]
F6UE82
ENST00000435314.5