RASGRP3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007265Biological processRas protein signal transduction
GO_0000165Biological processMAPK cascade
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0032045Cellular componentguanyl-nucleotide exchange factor complex
GO_0005886Cellular componentplasma membrane
GO_0019900Molecular functionkinase binding
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding
GO_0019992Molecular functiondiacylglycerol binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameRASGRP3
Protein nameRAS guanyl releasing protein 3
Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)
SynonymsKIAA0846
GRP3
DescriptionFUNCTION: Guanine nucleotide exchange factor (GEF) for Ras and Rap1. .

AccessionsC9JWP0
H7C352
C9J9C9
ENST00000437184.5
ENST00000442390.5
C9K0P4
ENST00000403687.8 [Q8IV61-1]
ENST00000402538.7 [Q8IV61-1]
ENST00000419772.1
Q8IV61
ENST00000407811.5 [Q8IV61-2]
C9JSS2
ENST00000423159.5
ENST00000425210.5
C9IYA5
ENST00000444784.5