RAMAC report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0106005Biological processRNA 5'-cap (guanine-N7)-methylation
GO_0006370Biological process7-methylguanosine mRNA capping
GO_0032259Biological processmethylation
GO_0031533Cellular componentmRNA capping enzyme complex
GO_0160130Cellular componentmRNA cap methyltransferase RNMT:RAMAC complex
GO_0005634Cellular componentnucleus
GO_0008047Molecular functionenzyme activator activity
GO_0140677Molecular functionmolecular function activator activity
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameRAMAC
Protein nameRNA guanine-N7 methyltransferase activating subunit (Protein FAM103A1) (RNA guanine-7 methyltransferase activating subunit) (RNMT-activating mRNA cap methyltransferase subunit) (RNMT-activating mini protein) (RAM)
SynonymsC15orf18
RAMMET
FAM103A1
DescriptionFUNCTION: Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs . Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT . Regulates RNMT expression by a post-transcriptional stabilizing mechanism . Binds RNA . .

AccessionsENST00000304191.4
Q9BTL3