Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 5 studies | 22% ± 7% | |
ciliated cell | 5 studies | 32% ± 10% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 21% ± 4% | |
epithelial cell | 4 studies | 43% ± 14% | |
endothelial cell | 4 studies | 24% ± 8% | |
fibroblast | 4 studies | 20% ± 3% | |
B cell | 3 studies | 31% ± 4% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 20% ± 2% | |
CD4-positive, alpha-beta T cell | 3 studies | 23% ± 2% | |
CD8-positive, alpha-beta T cell | 3 studies | 24% ± 4% | |
precursor B cell | 3 studies | 27% ± 8% | |
basal cell | 3 studies | 38% ± 17% | |
naive B cell | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 228.01 | 180 / 180 | 100% | 12.45 | 430 / 430 |
prostate | 100% | 221.89 | 245 / 245 | 100% | 9.09 | 502 / 502 |
esophagus | 100% | 292.32 | 1444 / 1445 | 100% | 7.64 | 183 / 183 |
breast | 100% | 268.60 | 459 / 459 | 100% | 10.21 | 1117 / 1118 |
bladder | 100% | 209.71 | 21 / 21 | 100% | 8.97 | 503 / 504 |
skin | 100% | 371.40 | 1809 / 1809 | 100% | 8.91 | 470 / 472 |
thymus | 100% | 219.76 | 652 / 653 | 100% | 8.67 | 603 / 605 |
liver | 100% | 188.27 | 226 / 226 | 100% | 7.57 | 404 / 406 |
uterus | 99% | 227.44 | 169 / 170 | 100% | 10.86 | 459 / 459 |
stomach | 100% | 236.87 | 358 / 359 | 100% | 7.58 | 285 / 286 |
intestine | 100% | 239.37 | 966 / 966 | 99% | 7.71 | 521 / 527 |
brain | 99% | 191.96 | 2610 / 2642 | 100% | 6.91 | 705 / 705 |
adrenal gland | 100% | 256.75 | 258 / 258 | 99% | 9.34 | 227 / 230 |
pancreas | 99% | 173.05 | 325 / 328 | 99% | 7.43 | 177 / 178 |
kidney | 100% | 185.83 | 89 / 89 | 98% | 5.51 | 887 / 901 |
lung | 97% | 173.39 | 563 / 578 | 100% | 8.87 | 1152 / 1155 |
lymph node | 0% | 0 | 0 / 0 | 100% | 8.72 | 29 / 29 |
spleen | 100% | 232.32 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 9.09 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.64 | 1 / 1 |
adipose | 100% | 213.17 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 274.56 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 218.13 | 1333 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 5.45 | 78 / 80 |
heart | 94% | 133.87 | 811 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 88% | 260.06 | 814 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0106005 | Biological process | RNA 5'-cap (guanine-N7)-methylation |
GO_0006370 | Biological process | 7-methylguanosine mRNA capping |
GO_0032259 | Biological process | methylation |
GO_0031533 | Cellular component | mRNA capping enzyme complex |
GO_0160130 | Cellular component | mRNA cap methyltransferase RNMT:RAMAC complex |
GO_0005634 | Cellular component | nucleus |
GO_0008047 | Molecular function | enzyme activator activity |
GO_0140677 | Molecular function | molecular function activator activity |
GO_0005515 | Molecular function | protein binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | RAMAC |
Protein name | RNA guanine-N7 methyltransferase activating subunit (Protein FAM103A1) (RNA guanine-7 methyltransferase activating subunit) (RNMT-activating mRNA cap methyltransferase subunit) (RNMT-activating mini protein) (RAM) |
Synonyms | C15orf18 RAMMET FAM103A1 |
Description | FUNCTION: Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs . Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT . Regulates RNMT expression by a post-transcriptional stabilizing mechanism . Binds RNA . . |
Accessions | ENST00000304191.4 Q9BTL3 |