RALGDS report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007265Biological processRas protein signal transduction
GO_0005903Cellular componentbrush border
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005634Cellular componentnucleus
GO_0030695Molecular functionGTPase regulator activity
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRALGDS
Protein nameRal guanine nucleotide dissociation stimulator
FLJ00185 protein (Ral guanine nucleotide dissociation stimulator, isoform CRA_b)
Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF)
SynonymsKIAA1308
hCG_31468
FLJ00185
RGF
DescriptionFUNCTION: Functions as a guanine nucleotide exchange factor (GEF) activating either RalA or RalB GTPases and plays an important role in intracellular transport. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap (By similarity). During bacterial clearance, recognizes 'Lys-33'-linked polyubiquitinated TRAF3 and subsequently mediates assembly of the exocyst complex . .

AccessionsENST00000477660.1
Q12967
A0A2R8YE90
Q9HAY0
ENST00000424572.1
ENST00000460587.1
ENST00000372062.8 [Q12967-4]
Q9HAX9
Q5T7U6
ENST00000372047.7 [Q12967-6]
ENST00000393157.8 [Q12967-5]
ENST00000393160.7 [Q12967-3]
Q9HAX8
A0A2R8YEX4
ENST00000372050.8 [Q12967-1]
Q8TEK9