Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 24 studies | 29% ± 12% | |
mast cell | 12 studies | 23% ± 8% | |
non-classical monocyte | 12 studies | 27% ± 12% | |
endothelial cell of artery | 11 studies | 31% ± 13% | |
endothelial cell of vascular tree | 9 studies | 24% ± 3% | |
endothelial cell of lymphatic vessel | 8 studies | 27% ± 9% | |
classical monocyte | 6 studies | 27% ± 9% | |
vein endothelial cell | 6 studies | 22% ± 5% | |
capillary endothelial cell | 6 studies | 26% ± 13% | |
ciliated cell | 6 studies | 25% ± 4% | |
neutrophil | 5 studies | 19% ± 3% | |
epithelial cell | 5 studies | 32% ± 11% | |
macrophage | 5 studies | 21% ± 4% | |
fibroblast | 4 studies | 20% ± 5% | |
monocyte | 4 studies | 20% ± 3% | |
basal cell | 4 studies | 21% ± 5% | |
conventional dendritic cell | 3 studies | 28% ± 6% | |
hematopoietic precursor cell | 3 studies | 21% ± 2% | |
myeloid cell | 3 studies | 23% ± 5% | |
GABAergic neuron | 3 studies | 21% ± 3% | |
glutamatergic neuron | 3 studies | 28% ± 6% | |
dendritic cell | 3 studies | 30% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4125.33 | 1445 / 1445 | 100% | 98.08 | 183 / 183 |
intestine | 100% | 3988.40 | 966 / 966 | 100% | 91.76 | 527 / 527 |
stomach | 100% | 2476.77 | 359 / 359 | 100% | 85.86 | 286 / 286 |
lung | 100% | 4513.84 | 577 / 578 | 100% | 106.05 | 1155 / 1155 |
prostate | 100% | 3908.30 | 245 / 245 | 100% | 96.04 | 501 / 502 |
uterus | 100% | 3699.04 | 170 / 170 | 100% | 89.35 | 458 / 459 |
ovary | 100% | 2337.02 | 180 / 180 | 100% | 61.21 | 429 / 430 |
breast | 100% | 4396.15 | 459 / 459 | 99% | 87.98 | 1112 / 1118 |
bladder | 100% | 3737.52 | 21 / 21 | 99% | 79.57 | 501 / 504 |
brain | 100% | 3185.26 | 2629 / 2642 | 100% | 53.50 | 704 / 705 |
thymus | 100% | 2898.92 | 652 / 653 | 100% | 71.76 | 602 / 605 |
skin | 100% | 3423.09 | 1808 / 1809 | 99% | 91.53 | 469 / 472 |
kidney | 100% | 4544.63 | 89 / 89 | 98% | 116.97 | 887 / 901 |
adrenal gland | 100% | 3329.82 | 258 / 258 | 96% | 54.44 | 221 / 230 |
pancreas | 88% | 1080.85 | 289 / 328 | 99% | 98.71 | 177 / 178 |
liver | 79% | 1076.88 | 178 / 226 | 89% | 34.75 | 361 / 406 |
adipose | 100% | 5024.71 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 57.38 | 29 / 29 |
spleen | 100% | 4702.01 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 99.13 | 45 / 45 |
blood vessel | 100% | 2919.66 | 1333 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 11126.63 | 927 / 929 | 0% | 0 | 0 / 0 |
heart | 99% | 2795.71 | 855 / 861 | 0% | 0 | 0 / 0 |
muscle | 96% | 1717.75 | 772 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 46.45 | 75 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_2000786 | Biological process | positive regulation of autophagosome assembly |
GO_0031623 | Biological process | receptor internalization |
GO_0060178 | Biological process | regulation of exocyst localization |
GO_0032092 | Biological process | positive regulation of protein binding |
GO_0007165 | Biological process | signal transduction |
GO_0051301 | Biological process | cell division |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0001928 | Biological process | regulation of exocyst assembly |
GO_0009267 | Biological process | cellular response to starvation |
GO_0045742 | Biological process | positive regulation of epidermal growth factor receptor signaling pathway |
GO_0006915 | Biological process | apoptotic process |
GO_0071360 | Biological process | cellular response to exogenous dsRNA |
GO_0032091 | Biological process | negative regulation of protein binding |
GO_0071902 | Biological process | positive regulation of protein serine/threonine kinase activity |
GO_0030496 | Cellular component | midbody |
GO_0005886 | Cellular component | plasma membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0019003 | Molecular function | GDP binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0003925 | Molecular function | G protein activity |
GO_0005525 | Molecular function | GTP binding |
GO_0051117 | Molecular function | ATPase binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | RALB |
Protein name | Alternative protein RALB Ras-related protein Ral-B (EC 3.6.5.2) RAS like proto-oncogene B |
Synonyms | |
Description | FUNCTION: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking . Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles (By similarity). Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells (By similarity). Required for suppression of apoptosis . In late stages of cytokinesis, upon completion of the bridge formation between dividing cells, mediates exocyst recruitment to the midbody to drive abscission . Involved in ligand-dependent receptor mediated endocytosis of the EGF and insulin receptors . . |
Accessions | ENST00000449649.1 F8WEQ6 ENST00000447591.5 ENST00000631312.2 P11234 C9JQB3 ENST00000412383.5 C9J6B1 ENST00000431732.5 C9JYR1 ENST00000272519.10 [P11234-1] ENST00000420510.5 [P11234-1] L8E7S5 |