PWP1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	16 studies	24% ± 7%	Explore
naive B cell	15 studies	22% ± 5%	Explore
memory B cell	15 studies	24% ± 5%	Explore
natural killer cell	9 studies	22% ± 4%	Explore
endothelial cell	8 studies	26% ± 8%	Explore
CD8-positive, alpha-beta T cell	8 studies	21% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	18% ± 2%	Explore
epithelial cell	7 studies	31% ± 14%	Explore
CD4-positive, alpha-beta T cell	6 studies	21% ± 6%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	20% ± 3%	Explore
fibroblast	6 studies	25% ± 7%	Explore
regulatory T cell	6 studies	20% ± 4%	Explore
plasmacytoid dendritic cell	6 studies	22% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
pericyte	5 studies	19% ± 3%	Explore
GABAergic neuron	5 studies	26% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	17% ± 1%	Explore
precursor B cell	4 studies	22% ± 2%	Explore
myofibroblast cell	4 studies	18% ± 1%	Explore
immature B cell	4 studies	19% ± 4%	Explore
astrocyte	4 studies	23% ± 6%	Explore
ciliated cell	4 studies	28% ± 5%	Explore
abnormal cell	4 studies	27% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	21% ± 2%	Explore
glutamatergic neuron	4 studies	35% ± 12%	Explore
basal cell	4 studies	26% ± 7%	Explore
gamma-delta T cell	4 studies	25% ± 15%	Explore
hematopoietic precursor cell	3 studies	25% ± 7%	Explore
smooth muscle cell	3 studies	21% ± 1%	Explore
pro-B cell	3 studies	21% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	19% ± 0%	Explore
macrophage	3 studies	20% ± 2%	Explore
dendritic cell	3 studies	31% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	19% ± 5%	Explore
interneuron	3 studies	29% ± 15%	Explore
neuron	3 studies	28% ± 10%	Explore
oligodendrocyte	3 studies	18% ± 1%	Explore
connective tissue cell	3 studies	21% ± 3%	Explore
erythroblast	3 studies	28% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	23% ± 8%	Explore
double negative thymocyte	3 studies	27% ± 12%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 1%	Explore
T cell	3 studies	17% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	7 studies	20% ± 5%	Explore
lung	5 studies	21% ± 5%	Explore
brain	5 studies	26% ± 7%	Explore
liver	3 studies	29% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	2714.29	21 / 21	100%	66.36	504 / 504
breast	100%	2889.68	459 / 459	100%	73.06	1118 / 1118
esophagus	100%	2538.17	1445 / 1445	100%	59.81	183 / 183
liver	100%	1223.10	226 / 226	100%	40.30	406 / 406
ovary	100%	2744.44	180 / 180	100%	51.06	430 / 430
skin	100%	3573.05	1809 / 1809	100%	83.04	472 / 472
stomach	100%	1960.91	359 / 359	100%	56.69	286 / 286
uterus	100%	2746.72	170 / 170	100%	66.95	459 / 459
kidney	100%	1807.39	89 / 89	100%	58.46	900 / 901
lung	100%	2018.75	577 / 578	100%	62.57	1155 / 1155
intestine	100%	2482.74	966 / 966	100%	60.52	526 / 527
prostate	100%	2100.13	245 / 245	100%	53.28	501 / 502
pancreas	100%	1654.51	327 / 328	100%	50.83	178 / 178
thymus	100%	2241.73	653 / 653	100%	56.84	603 / 605
brain	100%	1856.92	2629 / 2642	100%	75.09	705 / 705
adrenal gland	100%	2132.72	258 / 258	99%	50.24	227 / 230
adipose	100%	3005.03	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2832.79	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	63.60	80 / 80
lymph node	0%	0	0 / 0	100%	86.73	29 / 29
spleen	100%	2382.85	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	65.24	45 / 45
ureter	0%	0	0 / 0	100%	48.82	1 / 1
muscle	100%	1380.39	799 / 803	0%	0	0 / 0
heart	96%	1071.18	826 / 861	0%	0	0 / 0
peripheral blood	85%	1596.85	791 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006351	Biological process	DNA-templated transcription
GO_0033140	Biological process	negative regulation of peptidyl-serine phosphorylation of STAT protein
GO_1901838	Biological process	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
GO_2000738	Biological process	positive regulation of stem cell differentiation
GO_0006364	Biological process	rRNA processing
GO_0005730	Cellular component	nucleolus
GO_0005694	Cellular component	chromosome
GO_0005794	Cellular component	Golgi apparatus
GO_0005634	Cellular component	nucleus
GO_1990889	Molecular function	H4K20me3 modified histone binding
GO_0140713	Molecular function	histone chaperone activity

IV. Literature review

[source]

Gene name	PWP1
Protein name	PWP1 homolog, endonuclein PWP1 homolog (S. cerevisiae) Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502) PWP1 homolog, endonuclein (cDNA FLJ51513, highly similar to Periodic tryptophan protein 1 homolog) PWP1 protein
Synonyms
Description	FUNCTION: Chromatin-associated factor that regulates transcription . Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription . Regulates the epigenetic status of rDNA . .
Accessions	Q13610 F8VZ56 Q6PKI5 ENST00000552760.5 [Q13610-2] Q05BL3 Q86X79 Q9BV37 B4DJV5 ENST00000541166.1 Q6PIN4 ENST00000412830.8 [Q13610-1] ENST00000547995.5

PWP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review