Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 23 studies | 68% ± 19% | |
oligodendrocyte precursor cell | 16 studies | 91% ± 11% | |
basal cell | 11 studies | 33% ± 9% | |
GABAergic neuron | 7 studies | 46% ± 23% | |
interneuron | 7 studies | 38% ± 15% | |
glutamatergic neuron | 6 studies | 32% ± 11% | |
retina horizontal cell | 6 studies | 31% ± 10% | |
Mueller cell | 6 studies | 45% ± 19% | |
glial cell | 5 studies | 41% ± 22% | |
endothelial cell | 4 studies | 44% ± 25% | |
oligodendrocyte | 4 studies | 26% ± 10% | |
neuron | 4 studies | 28% ± 11% | |
precursor cell | 3 studies | 48% ± 20% | |
macrophage | 3 studies | 47% ± 26% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 85% ± 9% | |
GABAergic interneuron | 3 studies | 25% ± 6% | |
ciliated cell | 3 studies | 21% ± 5% | |
retinal pigment epithelial cell | 3 studies | 21% ± 1% | |
glycinergic amacrine cell | 3 studies | 47% ± 13% | |
neural progenitor cell | 3 studies | 66% ± 34% | |
ependymal cell | 3 studies | 73% ± 19% | |
Schwann cell | 3 studies | 49% ± 29% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 13 studies | 38% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 13117.15 | 2635 / 2642 | 100% | 691.06 | 702 / 705 |
skin | 70% | 2856.56 | 1273 / 1809 | 68% | 52.79 | 323 / 472 |
esophagus | 49% | 996.62 | 713 / 1445 | 45% | 22.94 | 83 / 183 |
stomach | 73% | 1211.26 | 261 / 359 | 3% | 0.74 | 10 / 286 |
tonsil | 0% | 0 | 0 / 0 | 64% | 17.22 | 29 / 45 |
lung | 14% | 223.60 | 83 / 578 | 39% | 18.15 | 451 / 1155 |
intestine | 43% | 974.52 | 419 / 966 | 2% | 0.38 | 11 / 527 |
uterus | 2% | 24.63 | 3 / 170 | 28% | 7.99 | 128 / 459 |
eye | 0% | 0 | 0 / 0 | 16% | 2.41 | 13 / 80 |
breast | 10% | 144.17 | 47 / 459 | 5% | 1.47 | 54 / 1118 |
bladder | 5% | 52.81 | 1 / 21 | 9% | 3.70 | 47 / 504 |
prostate | 9% | 148.52 | 22 / 245 | 2% | 0.50 | 11 / 502 |
blood vessel | 8% | 136.10 | 106 / 1335 | 0% | 0 | 0 / 0 |
adipose | 8% | 143.81 | 92 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 2% | 19.59 | 4 / 258 | 3% | 0.50 | 8 / 230 |
pancreas | 0% | 3.40 | 1 / 328 | 3% | 0.70 | 6 / 178 |
heart | 2% | 29.70 | 21 / 861 | 0% | 0 | 0 / 0 |
thymus | 0% | 0 | 0 / 653 | 1% | 0.30 | 5 / 605 |
kidney | 0% | 0 | 0 / 89 | 0% | 0.08 | 3 / 901 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0031641 | Biological process | regulation of myelination |
GO_0002244 | Biological process | hematopoietic progenitor cell differentiation |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0007611 | Biological process | learning or memory |
GO_0035335 | Biological process | peptidyl-tyrosine dephosphorylation |
GO_0007409 | Biological process | axonogenesis |
GO_0048714 | Biological process | positive regulation of oligodendrocyte differentiation |
GO_0048709 | Biological process | oligodendrocyte differentiation |
GO_0007417 | Biological process | central nervous system development |
GO_0070445 | Biological process | regulation of oligodendrocyte progenitor proliferation |
GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0045202 | Cellular component | synapse |
GO_0072534 | Cellular component | perineuronal net |
GO_0005001 | Molecular function | transmembrane receptor protein tyrosine phosphatase activity |
GO_0005178 | Molecular function | integrin binding |
GO_0005515 | Molecular function | protein binding |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | PTPRZ1 |
Protein name | Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (Protein-tyrosine phosphatase receptor type Z polypeptide 1) (Protein-tyrosine phosphatase receptor type Z polypeptide 2) (R-PTP-zeta-2) Protein tyrosine phosphatase receptor type Z1 protein-tyrosine-phosphatase (EC 3.1.3.48) |
Synonyms | PTPZ PTPRZ PTPRZ2 HTPZP2 |
Description | FUNCTION: Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity). . |
Accessions | ENST00000650826.1 ENST00000651390.1 ENST00000393386.7 [P23471-1] ENST00000651841.1 ENST00000650728.1 A0A494C1F0 ENST00000651842.1 A0A494C1J5 ENST00000650681.1 A0A494C0U4 ENST00000652298.1 [P23471-2] A0A494C1B4 ENST00000651863.1 ENST00000652054.1 P23471 A0A494C036 A0A494C0V2 ENST00000651065.1 ENST00000651320.1 A0A494C1R4 ENST00000652708.1 A0A494C055 ENST00000449182.1 [P23471-3] A0A494C087 A0A494C1H9 |