PRSS23 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	44 studies	42% ± 21%	Explore
endothelial cell of lymphatic vessel	26 studies	55% ± 20%	Explore
fibroblast	24 studies	31% ± 16%	Explore
natural killer cell	21 studies	29% ± 8%	Explore
pericyte	18 studies	39% ± 21%	Explore
basal cell	15 studies	45% ± 25%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	34% ± 10%	Explore
endothelial cell of vascular tree	14 studies	43% ± 12%	Explore
capillary endothelial cell	13 studies	35% ± 10%	Explore
vein endothelial cell	13 studies	53% ± 17%	Explore
smooth muscle cell	13 studies	30% ± 14%	Explore
endothelial cell of artery	11 studies	42% ± 16%	Explore
mature NK T cell	10 studies	26% ± 9%	Explore
adipocyte	9 studies	41% ± 22%	Explore
connective tissue cell	8 studies	38% ± 15%	Explore
mesothelial cell	8 studies	36% ± 12%	Explore
epithelial cell	7 studies	35% ± 21%	Explore
respiratory goblet cell	7 studies	68% ± 24%	Explore
myofibroblast cell	7 studies	29% ± 18%	Explore
ciliated cell	6 studies	29% ± 13%	Explore
club cell	5 studies	65% ± 22%	Explore
ionocyte	5 studies	29% ± 13%	Explore
secretory cell	5 studies	67% ± 17%	Explore
adventitial cell	5 studies	25% ± 6%	Explore
deuterosomal cell	4 studies	38% ± 13%	Explore
GABAergic neuron	4 studies	28% ± 7%	Explore
abnormal cell	4 studies	21% ± 3%	Explore
CD8-positive, alpha-beta T cell	4 studies	22% ± 4%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	22% ± 4%	Explore
glutamatergic neuron	4 studies	41% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	21% ± 4%	Explore
duct epithelial cell	3 studies	37% ± 26%	Explore
pancreatic D cell	3 studies	56% ± 13%	Explore
type B pancreatic cell	3 studies	55% ± 23%	Explore
endothelial cell of sinusoid	3 studies	37% ± 14%	Explore
retinal pigment epithelial cell	3 studies	24% ± 7%	Explore
glial cell	3 studies	23% ± 4%	Explore
astrocyte	3 studies	35% ± 13%	Explore
pancreatic ductal cell	3 studies	55% ± 9%	Explore
Schwann cell	3 studies	39% ± 12%	Explore
gamma-delta T cell	3 studies	21% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	12 studies	26% ± 13%	Explore
pancreas	4 studies	31% ± 11%	Explore
adipose	4 studies	31% ± 9%	Explore
uterus	3 studies	21% ± 4%	Explore
breast	3 studies	16% ± 0%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	7540.41	244 / 245	98%	42.10	494 / 502
breast	100%	6376.75	458 / 459	95%	89.48	1057 / 1118
thymus	99%	6232.78	647 / 653	92%	88.53	555 / 605
stomach	99%	6668.61	357 / 359	91%	41.17	259 / 286
lung	100%	8779.07	577 / 578	90%	37.71	1035 / 1155
intestine	98%	10796.52	950 / 966	91%	40.46	478 / 527
bladder	100%	10944.71	21 / 21	83%	36.53	418 / 504
uterus	99%	10316.62	169 / 170	76%	31.58	348 / 459
kidney	94%	4266.27	84 / 89	76%	49.32	683 / 901
ovary	87%	3453.48	156 / 180	78%	25.94	336 / 430
skin	78%	5280.22	1412 / 1809	84%	42.51	397 / 472
adrenal gland	88%	2901.16	226 / 258	69%	16.99	158 / 230
esophagus	76%	3106.93	1103 / 1445	71%	18.97	130 / 183
pancreas	43%	948.83	142 / 328	95%	49.64	169 / 178
ureter	0%	0	0 / 0	100%	85.98	1 / 1
blood vessel	100%	17154.88	1334 / 1335	0%	0	0 / 0
adipose	99%	7463.37	1195 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	60%	17.79	27 / 45
heart	56%	1770.80	485 / 861	0%	0	0 / 0
spleen	46%	974.79	112 / 241	0%	0	0 / 0
brain	8%	160.54	202 / 2642	34%	8.46	238 / 705
liver	14%	328.36	32 / 226	26%	7.14	106 / 406
muscle	36%	1036.14	287 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	28%	3.94	8 / 29
peripheral blood	7%	149.86	61 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	6%	0.88	5 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0