I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| neutrophil | 6 studies | 32% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| neutrophil | 6 studies | 32% ± 9% |
Insufficient scRNA-seq data for expression of PROK2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 875.83 | 565 / 578 | 19% | 0.59 | 215 / 1155 |
| spleen | 100% | 1541.08 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 81% | 11015.29 | 756 / 929 | 0% | 0 | 0 / 0 |
| stomach | 15% | 29.22 | 54 / 359 | 31% | 2.02 | 89 / 286 |
| liver | 40% | 68.61 | 90 / 226 | 1% | 0.03 | 5 / 406 |
| adipose | 38% | 103.14 | 457 / 1204 | 0% | 0 | 0 / 0 |
| ovary | 4% | 5.04 | 7 / 180 | 33% | 6.26 | 141 / 430 |
| intestine | 11% | 15.81 | 106 / 966 | 25% | 1.25 | 130 / 527 |
| esophagus | 9% | 15.50 | 125 / 1445 | 26% | 0.96 | 47 / 183 |
| adrenal gland | 3% | 3.19 | 7 / 258 | 31% | 4.47 | 72 / 230 |
| kidney | 26% | 26.98 | 23 / 89 | 7% | 0.16 | 64 / 901 |
| bladder | 14% | 70.05 | 3 / 21 | 18% | 1.16 | 89 / 504 |
| uterus | 9% | 18.02 | 15 / 170 | 18% | 1.18 | 84 / 459 |
| brain | 12% | 12.34 | 317 / 2642 | 14% | 0.42 | 99 / 705 |
| thymus | 24% | 25.44 | 155 / 653 | 1% | 0.02 | 6 / 605 |
| heart | 22% | 32.69 | 187 / 861 | 0% | 0 | 0 / 0 |
| breast | 12% | 14.10 | 56 / 459 | 3% | 0.11 | 28 / 1118 |
| blood vessel | 11% | 20.41 | 149 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 2% | 1.89 | 8 / 328 | 8% | 0.18 | 15 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.15 | 4 / 45 |
| prostate | 7% | 8.42 | 16 / 245 | 2% | 0.02 | 8 / 502 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.13 | 2 / 29 |
| skin | 1% | 0.70 | 17 / 1809 | 5% | 0.17 | 22 / 472 |
| muscle | 5% | 8.83 | 42 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0019233 | Biological process | sensory perception of pain |
| GO_0001525 | Biological process | angiogenesis |
| GO_0045987 | Biological process | positive regulation of smooth muscle contraction |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007218 | Biological process | neuropeptide signaling pathway |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0006954 | Biological process | inflammatory response |
| GO_0006935 | Biological process | chemotaxis |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0001935 | Biological process | endothelial cell proliferation |
| GO_0007623 | Biological process | circadian rhythm |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005515 | Molecular function | protein binding |
| GO_0001664 | Molecular function | G protein-coupled receptor binding |
| Gene name | PROK2 |
| Protein name | Prokineticin-2 (PK2) (Protein Bv8 homolog) |
| Synonyms | BV8 |
| Description | FUNCTION: May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle. |
| Accessions | ENST00000295619.4 [Q9HC23-1] ENST00000353065.7 [Q9HC23-2] Q9HC23 |
