PPP2R3C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030865Biological processcortical cytoskeleton organization
GO_0043029Biological processT cell homeostasis
GO_0035303Biological processregulation of dephosphorylation
GO_0001782Biological processB cell homeostasis
GO_0002759Biological processregulation of antimicrobial humoral response
GO_0045579Biological processpositive regulation of B cell differentiation
GO_0051900Biological processregulation of mitochondrial depolarization
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0048536Biological processspleen development
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005794Cellular componentGolgi apparatus
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene namePPP2R3C
Protein nameChromosome 14 open reading frame transcript variant 2 (Protein phosphatase 2 regulatory subunit B''gamma)
Protein phosphatase 2 regulatory subunit B''gamma
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C)
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
SynonymsG5PR
C14orf10
C14ORF10
DescriptionFUNCTION: May regulate MCM3AP phosphorylation through phosphatase recruitment (By similarity). May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex . May play a role in the activation-induced cell death of B-cells (By similarity). .

AccessionsQ969Q6
ENST00000555219.1
ENST00000557074.1
ENST00000554222.5
ENST00000553273.5
ENST00000554361.5
H0YJ16
G3V561
ENST00000557288.1
Q86US5
ENST00000555630.5
ENST00000554265.5
A0A0C4DGK2
ENST00000553282.1
ENST00000555614.5
ENST00000261475.10 [Q969Q6-1]
ENST00000554899.5
G3V5U8
G3V3V5
G3V3T9
ENST00000557217.5
ENST00000555644.5
G3V228
ENST00000554563.5
H0YJC5
ENST00000554488.5
H0YJV0
ENST00000555726.5
ENST00000557278.1
G3V2K1
H0YJR2