Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 7915.40 | 2642 / 2642 | 100% | 33.73 | 702 / 705 |
bladder | 71% | 1024.05 | 15 / 21 | 36% | 1.79 | 183 / 504 |
adrenal gland | 13% | 121.28 | 34 / 258 | 85% | 9.98 | 196 / 230 |
blood vessel | 90% | 1356.87 | 1195 / 1335 | 0% | 0 | 0 / 0 |
skin | 17% | 123.33 | 300 / 1809 | 38% | 1.45 | 180 / 472 |
intestine | 49% | 523.45 | 471 / 966 | 3% | 0.09 | 17 / 527 |
pancreas | 0% | 0 | 0 / 328 | 47% | 1.17 | 83 / 178 |
ovary | 0% | 0 | 0 / 180 | 45% | 2.30 | 194 / 430 |
lymph node | 0% | 0 | 0 / 0 | 34% | 0.72 | 10 / 29 |
uterus | 2% | 18.05 | 3 / 170 | 32% | 1.49 | 145 / 459 |
tonsil | 0% | 0 | 0 / 0 | 33% | 0.78 | 15 / 45 |
kidney | 19% | 141.67 | 17 / 89 | 11% | 0.29 | 98 / 901 |
thymus | 4% | 25.42 | 23 / 653 | 23% | 0.59 | 137 / 605 |
esophagus | 8% | 52.23 | 109 / 1445 | 16% | 0.37 | 29 / 183 |
lung | 0% | 1.02 | 1 / 578 | 23% | 0.73 | 262 / 1155 |
prostate | 13% | 132.83 | 31 / 245 | 3% | 0.04 | 14 / 502 |
peripheral blood | 13% | 104.81 | 121 / 929 | 0% | 0 | 0 / 0 |
stomach | 5% | 37.05 | 19 / 359 | 7% | 0.12 | 20 / 286 |
eye | 0% | 0 | 0 / 0 | 9% | 0.68 | 7 / 80 |
liver | 0% | 0 | 0 / 226 | 7% | 0.19 | 27 / 406 |
adipose | 5% | 42.75 | 64 / 1204 | 0% | 0 | 0 / 0 |
breast | 1% | 10.07 | 6 / 459 | 4% | 0.08 | 41 / 1118 |
heart | 5% | 30.39 | 40 / 861 | 0% | 0 | 0 / 0 |
spleen | 4% | 26.97 | 10 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006915 | Biological process | apoptotic process |
GO_0005741 | Cellular component | mitochondrial outer membrane |
GO_0000159 | Cellular component | protein phosphatase type 2A complex |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005739 | Cellular component | mitochondrion |
GO_0019888 | Molecular function | protein phosphatase regulator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | PPP2R2B |
Protein name | Protein phosphatase 2 regulatory subunit B Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta) Protein phosphatase 2 regulatory subunit Bbeta |
Synonyms | |
Description | FUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity). . |
Accessions | E9PCT7 ENST00000394409.7 [Q00005-1] ENST00000394414.5 [Q00005-5] ENST00000336640.10 [Q00005-2] E5RFC4 ENST00000512011.5 ENST00000394411.9 [Q00005-1] ENST00000512984.1 D6RB57 ENST00000512639.5 D6RGF9 ENST00000394413.7 [Q00005-4] ENST00000504198.5 [Q00005-3] ENST00000528601.5 ENST00000504565.1 ENST00000532154.5 ENST00000515880.5 ENST00000508267.5 Q00005 ENST00000453001.5 [Q00005-6] H0YA16 D6RF04 ENST00000508545.6 [Q00005-6] Q9NS07 |