PPP2R2B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0005741Cellular componentmitochondrial outer membrane
GO_0000159Cellular componentprotein phosphatase type 2A complex
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0005739Cellular componentmitochondrion
GO_0019888Molecular functionprotein phosphatase regulator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePPP2R2B
Protein nameProtein phosphatase 2 regulatory subunit B
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta)
Protein phosphatase 2 regulatory subunit Bbeta
Synonyms
DescriptionFUNCTION: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity). .

AccessionsE9PCT7
ENST00000394409.7 [Q00005-1]
ENST00000394414.5 [Q00005-5]
ENST00000336640.10 [Q00005-2]
E5RFC4
ENST00000512011.5
ENST00000394411.9 [Q00005-1]
ENST00000512984.1
D6RB57
ENST00000512639.5
D6RGF9
ENST00000394413.7 [Q00005-4]
ENST00000504198.5 [Q00005-3]
ENST00000528601.5
ENST00000504565.1
ENST00000532154.5
ENST00000515880.5
ENST00000508267.5
Q00005
ENST00000453001.5 [Q00005-6]
H0YA16
D6RF04
ENST00000508545.6 [Q00005-6]
Q9NS07