POU2F2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0098586Biological processcellular response to virus
GO_0006959Biological processhumoral immune response
GO_0032755Biological processpositive regulation of interleukin-6 production
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding
GO_0000976Molecular functiontranscription cis-regulatory region binding

IV. Literature review

[source]
Gene namePOU2F2
Protein namePOU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)
POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Octamer-binding transcription factor 1)
POU class 2 homeobox 2
POU domain protein
SynonymsOTF2
OCT2
DescriptionFUNCTION: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') . Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression . Modulates transcription transactivation by NR3C1, AR and PGR . .; FUNCTION: [Isoform 5]: Activates the U2 small nuclear RNA (snRNA) promoter. .

FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. .

FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. .

FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. .

AccessionsA0A1B0GUT9
ENST00000534559.5
ENST00000560398.5
ENST00000533548.1
ENST00000598842.2
E9PR37
ENST00000529067.5 [P09086-4]
H0YNW1
H0YKT2
ENST00000526816.6 [P09086-1]
M0R1I6
ENST00000526831.2
A0A0D9SF23
A0A8I5KYI8
ENST00000560804.6
ENST00000389341.9 [P09086-3]
B5ME60
P09086
A0A1B0GV81
ENST00000560558.5
H0YLL6
ENST00000342301.8
ENST00000528894.8
U3KQN1
ENST00000692977.1
H0YNG1
ENST00000524801.6
ENST00000529952.5 [P09086-2]
ENST00000532176.2
U3KQ96
ENST00000636631.1
A0A1B0GW97
ENST00000625670.2