Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 41 studies | 48% ± 15% | |
non-classical monocyte | 25 studies | 55% ± 20% | |
classical monocyte | 21 studies | 37% ± 18% | |
monocyte | 20 studies | 30% ± 12% | |
memory B cell | 20 studies | 49% ± 9% | |
naive B cell | 20 studies | 42% ± 10% | |
conventional dendritic cell | 18 studies | 28% ± 17% | |
macrophage | 17 studies | 25% ± 7% | |
dendritic cell | 13 studies | 27% ± 14% | |
regulatory T cell | 13 studies | 21% ± 7% | |
microglial cell | 12 studies | 37% ± 15% | |
plasma cell | 10 studies | 32% ± 12% | |
myeloid cell | 9 studies | 23% ± 9% | |
plasmacytoid dendritic cell | 5 studies | 23% ± 5% | |
neuron | 5 studies | 29% ± 13% | |
precursor B cell | 5 studies | 36% ± 15% | |
immature B cell | 5 studies | 46% ± 10% | |
plasmablast | 4 studies | 38% ± 12% | |
leukocyte | 4 studies | 22% ± 2% | |
IgG plasma cell | 4 studies | 18% ± 1% | |
interneuron | 4 studies | 30% ± 12% | |
mononuclear phagocyte | 4 studies | 30% ± 9% | |
germinal center B cell | 4 studies | 48% ± 20% | |
GABAergic neuron | 4 studies | 37% ± 13% | |
glutamatergic neuron | 4 studies | 47% ± 6% | |
CD4-positive, alpha-beta T cell | 3 studies | 21% ± 2% | |
hematopoietic precursor cell | 3 studies | 20% ± 3% | |
CD4-positive, alpha-beta memory T cell | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 96% | 1068.30 | 2543 / 2642 | 99% | 5.91 | 695 / 705 |
lung | 98% | 745.54 | 569 / 578 | 94% | 5.22 | 1091 / 1155 |
prostate | 97% | 705.24 | 238 / 245 | 89% | 2.46 | 448 / 502 |
esophagus | 82% | 478.03 | 1180 / 1445 | 98% | 5.94 | 179 / 183 |
bladder | 100% | 591.86 | 21 / 21 | 74% | 2.97 | 374 / 504 |
intestine | 100% | 1361.69 | 962 / 966 | 66% | 4.23 | 347 / 527 |
skin | 85% | 503.31 | 1529 / 1809 | 76% | 4.93 | 359 / 472 |
breast | 69% | 264.37 | 315 / 459 | 91% | 3.65 | 1017 / 1118 |
stomach | 69% | 295.58 | 249 / 359 | 77% | 7.53 | 219 / 286 |
uterus | 62% | 193.99 | 106 / 170 | 81% | 2.49 | 370 / 459 |
adrenal gland | 66% | 288.46 | 171 / 258 | 71% | 6.75 | 163 / 230 |
pancreas | 45% | 163.69 | 147 / 328 | 88% | 3.62 | 156 / 178 |
kidney | 46% | 221.15 | 41 / 89 | 81% | 3.22 | 729 / 901 |
ovary | 19% | 54.92 | 35 / 180 | 93% | 3.30 | 400 / 430 |
thymus | 49% | 297.29 | 322 / 653 | 57% | 2.47 | 347 / 605 |
lymph node | 0% | 0 | 0 / 0 | 100% | 117.44 | 29 / 29 |
spleen | 100% | 5982.86 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 5067.92 | 924 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 5.64 | 40 / 45 |
adipose | 77% | 345.10 | 930 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 77% | 343.21 | 1028 / 1335 | 0% | 0 | 0 / 0 |
liver | 24% | 72.70 | 55 / 226 | 22% | 0.64 | 88 / 406 |
heart | 10% | 34.27 | 88 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 10% | 0.21 | 8 / 80 |
muscle | 1% | 2.18 | 8 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0098586 | Biological process | cellular response to virus |
GO_0006959 | Biological process | humoral immune response |
GO_0032755 | Biological process | positive regulation of interleukin-6 production |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000785 | Cellular component | chromatin |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
Gene name | POU2F2 |
Protein name | POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2) POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Octamer-binding transcription factor 1) POU class 2 homeobox 2 POU domain protein |
Synonyms | OTF2 OCT2 |
Description | FUNCTION: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') . Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression . Modulates transcription transactivation by NR3C1, AR and PGR . .; FUNCTION: [Isoform 5]: Activates the U2 small nuclear RNA (snRNA) promoter. . FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. . FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. . FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. . |
Accessions | A0A1B0GUT9 ENST00000534559.5 ENST00000560398.5 ENST00000533548.1 ENST00000598842.2 E9PR37 ENST00000529067.5 [P09086-4] H0YNW1 H0YKT2 ENST00000526816.6 [P09086-1] M0R1I6 ENST00000526831.2 A0A0D9SF23 A0A8I5KYI8 ENST00000560804.6 ENST00000389341.9 [P09086-3] B5ME60 P09086 A0A1B0GV81 ENST00000560558.5 H0YLL6 ENST00000342301.8 ENST00000528894.8 U3KQN1 ENST00000692977.1 H0YNG1 ENST00000524801.6 ENST00000529952.5 [P09086-2] ENST00000532176.2 U3KQ96 ENST00000636631.1 A0A1B0GW97 ENST00000625670.2 |