PLGRKT report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006935Biological processchemotaxis
GO_0006954Biological processinflammatory response
GO_0010756Biological processpositive regulation of plasminogen activation
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePLGRKT
Protein namePlasminogen receptor (KT) (Plg-R(KT))
SynonymsC9orf46
MDS030
AD025
DescriptionFUNCTION: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9. .

AccessionsQ9HBL7
ENST00000223864.7