PHLDA1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	30 studies	37% ± 14%	Explore
pericyte	30 studies	48% ± 19%	Explore
endothelial cell	24 studies	32% ± 13%	Explore
macrophage	18 studies	27% ± 10%	Explore
smooth muscle cell	16 studies	42% ± 21%	Explore
endothelial cell of lymphatic vessel	13 studies	37% ± 16%	Explore
connective tissue cell	13 studies	34% ± 13%	Explore
basal cell	13 studies	36% ± 15%	Explore
regulatory T cell	13 studies	27% ± 11%	Explore
oligodendrocyte precursor cell	12 studies	41% ± 20%	Explore
T cell	11 studies	29% ± 9%	Explore
myofibroblast cell	9 studies	34% ± 19%	Explore
epithelial cell	9 studies	32% ± 13%	Explore
CD4-positive, alpha-beta T cell	9 studies	26% ± 7%	Explore
endothelial cell of vascular tree	9 studies	32% ± 17%	Explore
CD8-positive, alpha-beta T cell	8 studies	25% ± 7%	Explore
myeloid cell	7 studies	28% ± 10%	Explore
capillary endothelial cell	7 studies	35% ± 15%	Explore
gamma-delta T cell	7 studies	21% ± 8%	Explore
classical monocyte	6 studies	29% ± 14%	Explore
vein endothelial cell	6 studies	36% ± 9%	Explore
ionocyte	5 studies	44% ± 13%	Explore
abnormal cell	5 studies	35% ± 13%	Explore
innate lymphoid cell	5 studies	25% ± 6%	Explore
leukocyte	5 studies	26% ± 5%	Explore
mature NK T cell	5 studies	25% ± 9%	Explore
squamous epithelial cell	4 studies	41% ± 12%	Explore
GABAergic neuron	4 studies	20% ± 2%	Explore
endothelial cell of artery	4 studies	28% ± 5%	Explore
natural killer cell	4 studies	30% ± 8%	Explore
alveolar macrophage	4 studies	19% ± 4%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	30% ± 12%	Explore
melanocyte	4 studies	36% ± 12%	Explore
secretory cell	4 studies	26% ± 13%	Explore
mast cell	3 studies	32% ± 10%	Explore
Mueller cell	3 studies	39% ± 3%	Explore
CD4-positive helper T cell	3 studies	27% ± 8%	Explore
conventional dendritic cell	3 studies	25% ± 5%	Explore
monocyte	3 studies	31% ± 13%	Explore
muscle cell	3 studies	35% ± 8%	Explore
mucosal invariant T cell	3 studies	23% ± 8%	Explore
progenitor cell of mammary luminal epithelium	3 studies	37% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	11 studies	25% ± 7%	Explore
intestine	5 studies	27% ± 8%	Explore
uterus	5 studies	26% ± 5%	Explore
kidney	4 studies	25% ± 8%	Explore
breast	4 studies	26% ± 5%	Explore
ovary	3 studies	19% ± 3%	Explore
esophagus	3 studies	25% ± 1%	Explore
prostate	3 studies	45% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	98%	4567.32	1775 / 1809	99%	141.56	468 / 472
brain	98%	2263.81	2586 / 2642	99%	126.61	699 / 705
thymus	100%	5499.94	653 / 653	88%	63.33	531 / 605
lung	100%	6666.50	578 / 578	84%	37.49	968 / 1155
stomach	98%	3968.16	351 / 359	86%	39.30	246 / 286
adrenal gland	100%	4167.91	258 / 258	79%	33.35	181 / 230
kidney	99%	2996.81	88 / 89	79%	44.18	716 / 901
pancreas	83%	1560.30	272 / 328	95%	51.62	169 / 178
esophagus	82%	5015.91	1178 / 1445	92%	47.84	169 / 183
intestine	79%	1596.67	767 / 966	94%	53.81	495 / 527
uterus	88%	1644.64	149 / 170	81%	41.87	370 / 459
breast	100%	4049.38	458 / 459	67%	24.08	747 / 1118
bladder	76%	1413.81	16 / 21	83%	44.26	417 / 504
liver	84%	2559.96	189 / 226	52%	15.94	210 / 406
ovary	92%	3434.67	166 / 180	30%	8.43	128 / 430
prostate	96%	2147.44	234 / 245	23%	4.58	117 / 502
adipose	99%	4026.28	1195 / 1204	0%	0	0 / 0
spleen	99%	3532.14	239 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	94%	44.73	75 / 80
blood vessel	91%	2600.19	1215 / 1335	0%	0	0 / 0
heart	78%	1794.43	674 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	78%	34.31	35 / 45
muscle	41%	598.85	328 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	17%	2.68	5 / 29
peripheral blood	6%	82.74	58 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0045210	Biological process	FasL biosynthetic process
GO_0006915	Biological process	apoptotic process
GO_0043065	Biological process	positive regulation of apoptotic process
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0031410	Cellular component	cytoplasmic vesicle
GO_0005634	Cellular component	nucleus
GO_1901981	Molecular function	phosphatidylinositol phosphate binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PHLDA1
Protein name	Pleckstrin homology like domain family A member 1 Pleckstrin homology-like domain family A member 1 (Apoptosis-associated nuclear protein) (Proline- and glutamine-rich protein) (PQ-rich protein) (PQR protein) (Proline- and histidine-rich protein) (T-cell death-associated gene 51 protein) PHLDA1 protein
Synonyms	TDAG51 PHRIP
Description	FUNCTION: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation. .
Accessions	ENST00000266671.10 ENST00000602540.5 Q8WV24 A2BDE7 R4GND3

PHLDA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review