PDE4DIP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007098Biological processcentrosome cycle
GO_1903358Biological processregulation of Golgi organization
GO_0090063Biological processpositive regulation of microtubule nucleation
GO_0065003Biological processprotein-containing complex assembly
GO_0005813Cellular componentcentrosome
GO_0030016Cellular componentmyofibril
GO_0005794Cellular componentGolgi apparatus
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0019899Molecular functionenzyme binding
GO_0005515Molecular functionprotein binding
GO_0060090Molecular functionmolecular adaptor activity

IV. Literature review

[source]
Gene namePDE4DIP
Protein namePhosphodiesterase 4D interacting protein
CDK5 regulatory subunit-associated protein 2
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
PDE4DIP protein
SynonymsKIAA0454
KIAA0477
MMGL
RP4-791M13.2-009
CMYA2
DescriptionFUNCTION: Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). .; FUNCTION: [Isoform 13]: Participates in microtubule dynamics, promoting microtubule assembly. Depending upon the cell context, may act at the level of the Golgi apparatus or that of the centrosome . In complex with AKAP9, recruits CAMSAP2 to the Golgi apparatus and tethers non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement . In complex with AKAP9, EB1/MAPRE1 and CDK5RAP2, contributes to microtubules nucleation and extension from the centrosome to the cell periphery, a crucial process for directed cell migration, mitotic spindle orientation and cell-cycle progression . .

AccessionsH0YCH7
A0A994J5E0
A0A087WVQ4
A0A8Q3WM32
ENST00000530472.5 [Q5VU43-8]
ENST00000695765.1
ENST00000704840.1
A0A9L9PY76
E9PNE0
A0A087WWK4
ENST00000618504.4
Q6P470
ENST00000613995.4
ENST00000491426.3
A0A8Q3SI11
E9PS60
ENST00000530062.5
E9PJK3
ENST00000534536.5
ENST00000695766.1
ENST00000369356.8 [Q5VU43-4]
A0A8Q3SI65
ENST00000529945.2 [Q5VU43-13]
ENST00000695795.1
ENST00000479408.6
ENST00000695769.1
Q5VU43
ENST00000618462.4 [Q5VU43-3]
ENST00000369354.7 [Q5VU43-1]
E9PQG4
I1VE15
ENST00000524974.5
A0A087X0I1
A0A087WWI2
ENST00000585156.5
A0A087X229
E9PJU0
Q5TB27
Q8TBR0
ENST00000526445.1
ENST00000369349.7 [Q5VU43-6]
A0A075B749
ENST00000620605.4
ENST00000695768.1
ENST00000530130.2
ENST00000313431.13 [Q5VU43-2]
A7YY83
ENST00000695767.1
ENST00000619981.4
A0A087WWY1
A0A8Q3SI71
ENST00000369351.7 [Q5VU43-7]
A0A8Q3SI21
A0A087X041
ENST00000706647.1
ENST00000528129.5
A0A8Q3SI83
H0YCY0
ENST00000369347.8 [Q5VU43-11]
ENST00000621371.4
ENST00000616206.4
H0YEW6
A0A087WX83
ENST00000533259.1
A0A8Q3SI09
ENST00000695794.1
ENST00000617454.4