OTX2 | OmnibusX

Name	Number of supported studies	Average coverage
retinal rod cell	8 studies	43% ± 16%	Explore
retinal cone cell	7 studies	42% ± 13%	Explore
retinal bipolar neuron	5 studies	52% ± 10%	Explore
retinal pigment epithelial cell	5 studies	46% ± 16%	Explore
OFF-bipolar cell	3 studies	55% ± 4%	Explore
ON-bipolar cell	3 studies	67% ± 4%	Explore
rod bipolar cell	3 studies	61% ± 10%	Explore

Name	Number of supported studies	Average coverage
eye	8 studies	30% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	33%	348.44	877 / 2642	3%	0.88	21 / 705
eye	0%	0	0 / 0	19%	2.19	15 / 80
lung	0%	0	0 / 578	10%	1.06	111 / 1155
uterus	0%	0	0 / 170	8%	0.73	37 / 459
esophagus	0%	0	0 / 1445	5%	0.34	10 / 183
ovary	1%	0.36	1 / 180	2%	0.17	10 / 430
stomach	0%	0	0 / 359	3%	0.08	8 / 286
bladder	0%	0	0 / 21	2%	0.13	11 / 504
intestine	0%	0	0 / 966	1%	0.02	6 / 527
skin	0%	0.29	1 / 1809	1%	0.02	4 / 472
thymus	0%	0	0 / 653	1%	0.04	4 / 605
pancreas	0%	0	0 / 328	1%	0.02	1 / 178
liver	0%	0	0 / 226	0%	0.09	2 / 406
breast	0%	0	0 / 459	0%	0.02	5 / 1118
prostate	0%	0.27	1 / 245	0%	0	0 / 502
adrenal gland	0%	0.53	1 / 258	0%	0	0 / 230
kidney	0%	0	0 / 89	0%	0.00	1 / 901
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
blood vessel	0%	0	0 / 1335	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008589	Biological process	regulation of smoothened signaling pathway
GO_2000543	Biological process	positive regulation of gastrulation
GO_0030900	Biological process	forebrain development
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0090009	Biological process	primitive streak formation
GO_0071542	Biological process	dopaminergic neuron differentiation
GO_0065003	Biological process	protein-containing complex assembly
GO_0040019	Biological process	positive regulation of embryonic development
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0040036	Biological process	regulation of fibroblast growth factor receptor signaling pathway
GO_0030901	Biological process	midbrain development
GO_0007411	Biological process	axon guidance
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0032991	Cellular component	protein-containing complex
GO_0030426	Cellular component	growth cone
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0008190	Molecular function	eukaryotic initiation factor 4E binding
GO_0005515	Molecular function	protein binding

Gene name	OTX2
Protein name	Homeobox protein OTX2 Homeobox protein OTX2 (Orthodenticle homolog 2) Homeobox protein OTX2 (Orthodenticle homolog 2 (Drosophila), isoform CRA_b) Homeobox protein OTX2 (Orthodenticle homeobox 2) Orthodenticle homeobox 2
Synonyms	hCG_32530
Description	FUNCTION: Transcription factor probably involved in the development of the brain and the sense organs. Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'. .
Accessions	ENST00000554845 ENST00000673035.1 [P32243-1] ENST00000555804 ENST00000554559.5 ENST00000555006.5 [P32243-1] F1T0D1 A0A0H3W5S0 ENST00000339475.10 [P32243-1] ENST00000408990.8 [P32243-1] ENST00000673481.1 [P32243-2] ENST00000672264.2 [P32243-2] P32243 G3V3P9 ENST00000554788.5 A0A0A7NV78 A0A0A7NV24 ENST00000685244.1 [P32243-1] A0A0Y0SMK7 F1T0D0 ENST00000555804.2 [P32243-1] F1T0C9 G3V3J3 A0A5F9ZHY1 A0A0Y0SBK5 ENST00000672125.1 A0A0H3W5K0 ENST00000554845.2 [P32243-2]

OTX2 report