Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 23 studies | 32% ± 12% | |
fibroblast | 17 studies | 21% ± 6% | |
oligodendrocyte | 16 studies | 61% ± 18% | |
astrocyte | 16 studies | 44% ± 20% | |
macrophage | 15 studies | 31% ± 14% | |
smooth muscle cell | 14 studies | 23% ± 5% | |
pericyte | 14 studies | 24% ± 6% | |
oligodendrocyte precursor cell | 12 studies | 38% ± 17% | |
glutamatergic neuron | 11 studies | 58% ± 24% | |
microglial cell | 11 studies | 37% ± 13% | |
GABAergic neuron | 10 studies | 48% ± 26% | |
adipocyte | 10 studies | 52% ± 13% | |
endothelial cell of vascular tree | 9 studies | 25% ± 8% | |
endothelial cell of lymphatic vessel | 8 studies | 26% ± 3% | |
interneuron | 7 studies | 47% ± 29% | |
myeloid cell | 7 studies | 30% ± 9% | |
myofibroblast cell | 6 studies | 21% ± 5% | |
neuron | 6 studies | 36% ± 19% | |
retinal ganglion cell | 6 studies | 59% ± 23% | |
retinal rod cell | 6 studies | 35% ± 6% | |
ciliated cell | 6 studies | 20% ± 5% | |
capillary endothelial cell | 5 studies | 23% ± 9% | |
epithelial cell | 5 studies | 44% ± 16% | |
amacrine cell | 5 studies | 27% ± 9% | |
retinal cone cell | 5 studies | 30% ± 9% | |
cardiac muscle cell | 5 studies | 35% ± 9% | |
Mueller cell | 5 studies | 20% ± 2% | |
retinal pigment epithelial cell | 4 studies | 63% ± 10% | |
mucus secreting cell | 4 studies | 24% ± 0% | |
monocyte | 4 studies | 30% ± 13% | |
connective tissue cell | 4 studies | 17% ± 1% | |
alveolar macrophage | 4 studies | 38% ± 14% | |
basal cell | 4 studies | 35% ± 16% | |
goblet cell | 4 studies | 42% ± 20% | |
ionocyte | 3 studies | 30% ± 5% | |
hematopoietic precursor cell | 3 studies | 27% ± 8% | |
glomerular endothelial cell | 3 studies | 20% ± 3% | |
retinal bipolar neuron | 3 studies | 26% ± 8% | |
GABAergic interneuron | 3 studies | 47% ± 10% | |
glial cell | 3 studies | 38% ± 3% | |
mesothelial cell | 3 studies | 19% ± 5% | |
mononuclear phagocyte | 3 studies | 21% ± 4% | |
vein endothelial cell | 3 studies | 35% ± 16% | |
OFF-bipolar cell | 3 studies | 42% ± 22% | |
ON-bipolar cell | 3 studies | 44% ± 24% | |
rod bipolar cell | 3 studies | 38% ± 5% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 19% ± 2% | |
neural progenitor cell | 3 studies | 27% ± 9% | |
ependymal cell | 3 studies | 48% ± 18% | |
mast cell | 3 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 5810.24 | 459 / 459 | 99% | 29.53 | 1108 / 1118 |
brain | 99% | 7004.95 | 2608 / 2642 | 99% | 30.86 | 696 / 705 |
skin | 98% | 2237.30 | 1774 / 1809 | 99% | 37.86 | 466 / 472 |
kidney | 99% | 2390.63 | 88 / 89 | 98% | 26.92 | 879 / 901 |
prostate | 99% | 2444.73 | 242 / 245 | 97% | 17.48 | 489 / 502 |
ovary | 100% | 2866.46 | 180 / 180 | 95% | 12.73 | 407 / 430 |
esophagus | 98% | 3400.41 | 1411 / 1445 | 96% | 16.27 | 175 / 183 |
lung | 98% | 2565.82 | 568 / 578 | 95% | 15.23 | 1095 / 1155 |
thymus | 100% | 3318.66 | 650 / 653 | 92% | 11.69 | 556 / 605 |
uterus | 100% | 4775.69 | 170 / 170 | 85% | 11.08 | 390 / 459 |
stomach | 97% | 2633.03 | 350 / 359 | 81% | 9.17 | 231 / 286 |
bladder | 100% | 3842.19 | 21 / 21 | 78% | 9.79 | 392 / 504 |
adrenal gland | 99% | 4007.47 | 256 / 258 | 78% | 10.12 | 180 / 230 |
intestine | 100% | 4152.02 | 965 / 966 | 75% | 7.85 | 397 / 527 |
pancreas | 64% | 791.09 | 209 / 328 | 91% | 13.26 | 162 / 178 |
adipose | 100% | 6437.12 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 31.65 | 80 / 80 |
muscle | 100% | 7327.97 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.50 | 1 / 1 |
blood vessel | 100% | 3817.29 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 95% | 3375.52 | 814 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 11.29 | 41 / 45 |
liver | 24% | 279.32 | 55 / 226 | 58% | 5.18 | 234 / 406 |
spleen | 61% | 735.92 | 146 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 28% | 1.71 | 8 / 29 |
peripheral blood | 14% | 186.58 | 132 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008203 | Biological process | cholesterol metabolic process |
GO_0016192 | Biological process | vesicle-mediated transport |
GO_0006699 | Biological process | bile acid biosynthetic process |
GO_0006869 | Biological process | lipid transport |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005768 | Cellular component | endosome |
GO_0005829 | Cellular component | cytosol |
GO_0097038 | Cellular component | perinuclear endoplasmic reticulum |
GO_0005770 | Cellular component | late endosome |
GO_0005886 | Cellular component | plasma membrane |
GO_0044232 | Cellular component | organelle membrane contact site |
GO_0015485 | Molecular function | cholesterol binding |
GO_0005515 | Molecular function | protein binding |
GO_0005543 | Molecular function | phospholipid binding |
Gene name | OSBPL1A |
Protein name | Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1) Oxysterol binding protein like 1A Oxysterol-binding protein |
Synonyms | OSBP8 OSBPL1 ORP1 OSBPL1B hCG_2020467 |
Description | FUNCTION: Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A . Binds 25-hydroxycholesterol and cholesterol . . |
Accessions | ENST00000399441.4 ENST00000579851.5 Q6DKJ0 ENST00000584119.1 ENST00000319481.8 [Q9BXW6-1] ENST00000399443.7 [Q9BXW6-2] B0YJ56 Q9BXW6 ENST00000582645.5 J3KSG6 J3KTA6 J3QSB8 B7ZLX8 ENST00000578091.5 E7ER58 ENST00000578055.5 ENST00000357041.8 [Q9BXW6-4] J3KRT6 J3QLA2 ENST00000578013.1 J3QS61 Q6GSK5 |