NUBP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016226Biological processiron-sulfur cluster assembly
GO_0030030Biological processcell projection organization
GO_0005814Cellular componentcentriole
GO_0005929Cellular componentcilium
GO_0031616Cellular componentspindle pole centrosome
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0005524Molecular functionATP binding
GO_0140663Molecular functionATP-dependent FeS chaperone activity
GO_0051536Molecular functioniron-sulfur cluster binding
GO_0005515Molecular functionprotein binding
GO_0051539Molecular function4 iron, 4 sulfur cluster binding
GO_0046872Molecular functionmetal ion binding
GO_0000166Molecular functionnucleotide binding

IV. Literature review

[source]
Gene nameNUBP2
Protein nameNUBP iron-sulfur cluster assembly factor 2, cytosolic
Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2)
NUBP iron-sulfur cluster assembly factor 2, cytosolic (Nucleotide binding protein 2 (MinD homolog, E. coli), isoform CRA_d) (cDNA FLJ57200, highly similar to Nucleotide-binding protein 2)
SynonymshCG_42691
DescriptionFUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure. .

FUNCTION: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. .

AccessionsQ9Y5Y2
ENST00000562263.5
H3BQR2
H3BQE5
ENST00000568287.5
H3BRK5
H3BNF0
ENST00000569898.5
ENST00000565987.5
H3BRE1
ENST00000565134.5
ENST00000568706.1
ENST00000262302.14
ENST00000564227.5
ENST00000568834.5
B2RDN3
H3BNS4
ENST00000563136.5
B7Z6P0
H3BMW1