NRL report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010628Biological processpositive regulation of gene expression
GO_0007601Biological processvisual perception
GO_0046548Biological processretinal rod cell development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_1990841Molecular functionpromoter-specific chromatin binding
GO_0043522Molecular functionleucine zipper domain binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameNRL
Protein nameNeural retina leucine zipper
Neural retina-specific leucine zipper protein (NRL)
SynonymsD14S46E
DescriptionFUNCTION: Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B . Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 . Binds in a sequence-specific manner to the rhodopsin promoter . .

AccessionsENST00000646526.3 [P54845-1]
ENST00000642485.1 [P54845-2]
ENST00000645740.1 [P54845-2]
ENST00000643394.1 [P54845-1]
ENST00000396997.1 [P54845-1]
H0YNW2
ENST00000396995.1 [P54845-2]
ENST00000397002.6 [P54845-1]
ENST00000561028.6 [P54845-1]
ENST00000647376.1 [P54845-1]
ENST00000560550.1 [P54845-2]
P54845
ENST00000558280.1