Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 15 studies | 39% ± 19% | |
endothelial cell | 14 studies | 30% ± 10% | |
microglial cell | 11 studies | 30% ± 11% | |
oligodendrocyte precursor cell | 11 studies | 38% ± 18% | |
oligodendrocyte | 11 studies | 34% ± 12% | |
glutamatergic neuron | 10 studies | 42% ± 25% | |
adipocyte | 9 studies | 26% ± 5% | |
GABAergic neuron | 8 studies | 40% ± 22% | |
macrophage | 7 studies | 31% ± 9% | |
fibroblast | 7 studies | 25% ± 7% | |
interneuron | 6 studies | 40% ± 25% | |
endothelial cell of lymphatic vessel | 5 studies | 29% ± 8% | |
pericyte | 5 studies | 24% ± 8% | |
type I pneumocyte | 5 studies | 23% ± 7% | |
cardiac muscle cell | 4 studies | 29% ± 3% | |
retinal rod cell | 4 studies | 24% ± 4% | |
T cell | 4 studies | 22% ± 3% | |
myeloid cell | 4 studies | 20% ± 3% | |
monocyte | 4 studies | 22% ± 5% | |
smooth muscle cell | 4 studies | 23% ± 3% | |
type II pneumocyte | 4 studies | 19% ± 5% | |
neuron | 3 studies | 36% ± 12% | |
GABAergic interneuron | 3 studies | 25% ± 1% | |
Mueller cell | 3 studies | 21% ± 4% | |
glycinergic amacrine cell | 3 studies | 19% ± 5% | |
ependymal cell | 3 studies | 40% ± 16% | |
alveolar macrophage | 3 studies | 22% ± 8% | |
ciliated cell | 3 studies | 31% ± 8% | |
club cell | 3 studies | 22% ± 7% | |
natural killer cell | 3 studies | 21% ± 4% | |
lymphocyte | 3 studies | 32% ± 7% | |
granule cell | 3 studies | 27% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 1353.33 | 21 / 21 | 100% | 13.87 | 504 / 504 |
breast | 100% | 1286.79 | 459 / 459 | 100% | 16.80 | 1118 / 1118 |
esophagus | 100% | 1128.63 | 1445 / 1445 | 100% | 11.29 | 183 / 183 |
lung | 100% | 1226.92 | 578 / 578 | 100% | 13.87 | 1155 / 1155 |
ovary | 100% | 1679.96 | 180 / 180 | 100% | 12.38 | 430 / 430 |
prostate | 100% | 1317.69 | 245 / 245 | 100% | 12.46 | 502 / 502 |
stomach | 100% | 829.82 | 359 / 359 | 100% | 12.51 | 286 / 286 |
thymus | 100% | 1489.01 | 653 / 653 | 100% | 17.84 | 605 / 605 |
uterus | 100% | 1705.58 | 170 / 170 | 100% | 15.76 | 459 / 459 |
brain | 100% | 1181.72 | 2639 / 2642 | 100% | 18.53 | 705 / 705 |
skin | 100% | 1189.52 | 1809 / 1809 | 100% | 14.54 | 471 / 472 |
intestine | 100% | 1244.29 | 966 / 966 | 100% | 13.16 | 525 / 527 |
pancreas | 100% | 601.57 | 328 / 328 | 99% | 13.38 | 177 / 178 |
kidney | 100% | 1059.91 | 89 / 89 | 99% | 11.61 | 893 / 901 |
adrenal gland | 100% | 816.01 | 258 / 258 | 97% | 9.27 | 223 / 230 |
liver | 100% | 488.56 | 226 / 226 | 94% | 6.94 | 383 / 406 |
adipose | 100% | 1179.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1215.67 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 17.02 | 29 / 29 |
muscle | 100% | 1133.85 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1593.64 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.39 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.05 | 1 / 1 |
heart | 100% | 905.16 | 859 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 907.25 | 910 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 11.09 | 78 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
Gene name | NRF1 |
Protein name | Nuclear respiratory factor 1 Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal) |
Synonyms | |
Description | FUNCTION: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. |
Accessions | ENST00000393230.6 [Q16656-1] ENST00000353868.5 [Q16656-4] ENST00000454688.5 ENST00000393232.6 [Q16656-1] ENST00000311967.6 [Q16656-4] C9JP85 Q16656 ENST00000223190.8 [Q16656-1] |