NNT report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045454Biological processcell redox homeostasis
GO_0006740Biological processNADPH regeneration
GO_0098869Biological processcellular oxidant detoxification
GO_0072593Biological processreactive oxygen species metabolic process
GO_0001933Biological processnegative regulation of protein phosphorylation
GO_0033273Biological processresponse to vitamin
GO_0043066Biological processnegative regulation of apoptotic process
GO_0006099Biological processtricarboxylic acid cycle
GO_1903285Biological processpositive regulation of hydrogen peroxide catabolic process
GO_0032364Biological processintracellular oxygen homeostasis
GO_0010918Biological processpositive regulation of mitochondrial membrane potential
GO_1902600Biological processproton transmembrane transport
GO_0016020Cellular componentmembrane
GO_0005739Cellular componentmitochondrion
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005746Cellular componentmitochondrial respirasome
GO_0003957Molecular functionNAD(P)+ transhydrogenase (Si-specific) activity
GO_0051287Molecular functionNAD binding
GO_0050661Molecular functionNADP binding

IV. Literature review

[source]
Gene nameNNT
Protein nameNicotinamide nucleotide transhydrogenase
NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)
proton-translocating NAD(P)(+) transhydrogenase (EC 7.1.1.1)
Synonyms
DescriptionFUNCTION: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity). May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland . .

AccessionsENST00000512996.6
Q13423
A0A590UJV8
A0A590UJI3
A0A590UJM2
ENST00000657973.1
ENST00000653251.1
ENST00000662525.1
ENST00000660676.1
Q2TB59
ENST00000505678.6
ENST00000344920.9
Q8N5H5
ENST00000654405.1
A0A590UKC7
ENST00000660752.1
H0Y9R2
D6RAI5
ENST00000658729.1
A0A590UJM7
ENST00000264663.9
ENST00000656666.1
A0A590UK15
ENST00000670904.1
A0A590UJA4
ENST00000671668.1
ENST00000652986.1
ENST00000515208.1
ENST00000669601.1
E9PCX7
ENST00000512422.5
ENST00000657172.1
A0A590UK29
D6RCR6
D6RHU2
ENST00000503059.1
ENST00000654931.1