Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 10 studies | 30% ± 15% | |
endothelial cell | 9 studies | 30% ± 13% | |
glutamatergic neuron | 9 studies | 48% ± 26% | |
adipocyte | 9 studies | 30% ± 6% | |
oligodendrocyte precursor cell | 8 studies | 28% ± 12% | |
macrophage | 7 studies | 24% ± 6% | |
epithelial cell | 7 studies | 26% ± 5% | |
GABAergic neuron | 7 studies | 46% ± 22% | |
interneuron | 6 studies | 42% ± 23% | |
microglial cell | 6 studies | 26% ± 5% | |
fibroblast | 6 studies | 20% ± 3% | |
oligodendrocyte | 6 studies | 27% ± 8% | |
neuron | 5 studies | 29% ± 8% | |
cardiac muscle cell | 5 studies | 51% ± 11% | |
kidney loop of Henle epithelial cell | 4 studies | 21% ± 4% | |
B cell | 4 studies | 18% ± 2% | |
hepatocyte | 4 studies | 41% ± 9% | |
smooth muscle cell | 4 studies | 18% ± 3% | |
ionocyte | 3 studies | 24% ± 10% | |
GABAergic interneuron | 3 studies | 27% ± 6% | |
granule cell | 3 studies | 22% ± 3% | |
retinal ganglion cell | 3 studies | 25% ± 4% | |
myeloid cell | 3 studies | 19% ± 1% | |
plasma cell | 3 studies | 26% ± 8% | |
dendritic cell | 3 studies | 26% ± 7% | |
endothelial cell of lymphatic vessel | 3 studies | 20% ± 1% | |
monocyte | 3 studies | 18% ± 2% | |
transit amplifying cell | 3 studies | 31% ± 12% | |
mast cell | 3 studies | 20% ± 2% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 32% ± 3% | |
renal alpha-intercalated cell | 3 studies | 38% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 7619.27 | 226 / 226 | 99% | 32.67 | 403 / 406 |
thymus | 100% | 4088.38 | 653 / 653 | 99% | 20.74 | 599 / 605 |
kidney | 100% | 5042.53 | 89 / 89 | 99% | 37.96 | 892 / 901 |
brain | 98% | 3505.78 | 2600 / 2642 | 100% | 24.12 | 705 / 705 |
intestine | 100% | 4350.33 | 966 / 966 | 98% | 17.75 | 517 / 527 |
uterus | 100% | 2413.65 | 170 / 170 | 98% | 18.97 | 450 / 459 |
lung | 99% | 2951.19 | 572 / 578 | 99% | 22.57 | 1139 / 1155 |
stomach | 100% | 4962.25 | 359 / 359 | 98% | 19.01 | 279 / 286 |
bladder | 100% | 3878.43 | 21 / 21 | 97% | 17.62 | 491 / 504 |
ovary | 99% | 1933.29 | 179 / 180 | 98% | 14.31 | 421 / 430 |
esophagus | 98% | 3368.07 | 1422 / 1445 | 99% | 21.34 | 181 / 183 |
breast | 100% | 3417.88 | 459 / 459 | 97% | 19.99 | 1086 / 1118 |
pancreas | 99% | 2027.63 | 324 / 328 | 98% | 14.84 | 175 / 178 |
skin | 99% | 3100.14 | 1793 / 1809 | 98% | 33.74 | 461 / 472 |
adrenal gland | 99% | 3864.76 | 255 / 258 | 97% | 16.50 | 223 / 230 |
prostate | 100% | 2593.52 | 244 / 245 | 92% | 11.69 | 464 / 502 |
adipose | 100% | 4144.02 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 18.65 | 29 / 29 |
muscle | 100% | 18474.35 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2481.12 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.53 | 1 / 1 |
blood vessel | 100% | 3278.13 | 1333 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 17.44 | 44 / 45 |
heart | 98% | 15835.10 | 841 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 27.42 | 78 / 80 |
peripheral blood | 52% | 2320.46 | 479 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045454 | Biological process | cell redox homeostasis |
GO_0006740 | Biological process | NADPH regeneration |
GO_0098869 | Biological process | cellular oxidant detoxification |
GO_0072593 | Biological process | reactive oxygen species metabolic process |
GO_0001933 | Biological process | negative regulation of protein phosphorylation |
GO_0033273 | Biological process | response to vitamin |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0006099 | Biological process | tricarboxylic acid cycle |
GO_1903285 | Biological process | positive regulation of hydrogen peroxide catabolic process |
GO_0032364 | Biological process | intracellular oxygen homeostasis |
GO_0010918 | Biological process | positive regulation of mitochondrial membrane potential |
GO_1902600 | Biological process | proton transmembrane transport |
GO_0016020 | Cellular component | membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005746 | Cellular component | mitochondrial respirasome |
GO_0003957 | Molecular function | NAD(P)+ transhydrogenase (Si-specific) activity |
GO_0051287 | Molecular function | NAD binding |
GO_0050661 | Molecular function | NADP binding |
Gene name | NNT |
Protein name | Nicotinamide nucleotide transhydrogenase NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) proton-translocating NAD(P)(+) transhydrogenase (EC 7.1.1.1) |
Synonyms | |
Description | FUNCTION: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity). May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland . . |
Accessions | ENST00000512996.6 Q13423 A0A590UJV8 A0A590UJI3 A0A590UJM2 ENST00000657973.1 ENST00000653251.1 ENST00000662525.1 ENST00000660676.1 Q2TB59 ENST00000505678.6 ENST00000344920.9 Q8N5H5 ENST00000654405.1 A0A590UKC7 ENST00000660752.1 H0Y9R2 D6RAI5 ENST00000658729.1 A0A590UJM7 ENST00000264663.9 ENST00000656666.1 A0A590UK15 ENST00000670904.1 A0A590UJA4 ENST00000671668.1 ENST00000652986.1 ENST00000515208.1 ENST00000669601.1 E9PCX7 ENST00000512422.5 ENST00000657172.1 A0A590UK29 D6RCR6 D6RHU2 ENST00000503059.1 ENST00000654931.1 |