Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 30 studies | 32% ± 14% | |
pericyte | 19 studies | 33% ± 13% | |
smooth muscle cell | 18 studies | 32% ± 11% | |
connective tissue cell | 12 studies | 38% ± 17% | |
myofibroblast cell | 11 studies | 35% ± 15% | |
neuron | 7 studies | 43% ± 22% | |
mesothelial cell | 6 studies | 50% ± 17% | |
retinal ganglion cell | 4 studies | 57% ± 23% | |
ciliated cell | 4 studies | 28% ± 12% | |
endothelial cell | 4 studies | 27% ± 14% | |
GABAergic neuron | 4 studies | 24% ± 5% | |
neural crest cell | 3 studies | 32% ± 2% | |
retinal bipolar neuron | 3 studies | 25% ± 10% | |
basal cell | 3 studies | 27% ± 11% | |
amacrine cell | 3 studies | 38% ± 16% | |
retina horizontal cell | 3 studies | 28% ± 13% | |
retinal cone cell | 3 studies | 31% ± 18% | |
oligodendrocyte precursor cell | 3 studies | 29% ± 7% | |
interneuron | 3 studies | 25% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 2522.33 | 244 / 245 | 98% | 59.43 | 494 / 502 |
thymus | 99% | 1662.43 | 647 / 653 | 96% | 68.20 | 581 / 605 |
adrenal gland | 100% | 4200.00 | 258 / 258 | 88% | 211.93 | 202 / 230 |
brain | 89% | 3075.53 | 2361 / 2642 | 92% | 107.11 | 651 / 705 |
breast | 100% | 3153.34 | 459 / 459 | 79% | 24.65 | 879 / 1118 |
lung | 99% | 1790.27 | 572 / 578 | 77% | 29.50 | 889 / 1155 |
skin | 87% | 1818.58 | 1581 / 1809 | 79% | 61.03 | 374 / 472 |
ovary | 100% | 5569.08 | 180 / 180 | 64% | 30.17 | 277 / 430 |
bladder | 100% | 2802.19 | 21 / 21 | 63% | 22.35 | 320 / 504 |
esophagus | 99% | 2176.56 | 1429 / 1445 | 61% | 24.01 | 111 / 183 |
kidney | 88% | 987.38 | 78 / 89 | 68% | 32.13 | 615 / 901 |
intestine | 99% | 2521.99 | 959 / 966 | 57% | 15.13 | 298 / 527 |
pancreas | 59% | 441.62 | 195 / 328 | 92% | 46.83 | 164 / 178 |
stomach | 85% | 1482.95 | 304 / 359 | 59% | 19.33 | 169 / 286 |
uterus | 100% | 5226.78 | 170 / 170 | 40% | 20.43 | 183 / 459 |
adipose | 100% | 3761.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3364.81 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1676.39 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 34.05 | 1 / 1 |
heart | 96% | 1890.42 | 824 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 91% | 78.36 | 73 / 80 |
lymph node | 0% | 0 | 0 / 0 | 76% | 14.02 | 22 / 29 |
muscle | 46% | 367.13 | 366 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 42% | 9.76 | 19 / 45 |
liver | 3% | 27.63 | 7 / 226 | 28% | 13.17 | 115 / 406 |
peripheral blood | 0% | 4.90 | 4 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0019233 | Biological process | sensory perception of pain |
GO_0090312 | Biological process | positive regulation of protein deacetylation |
GO_0009791 | Biological process | post-embryonic development |
GO_0048011 | Biological process | neurotrophin TRK receptor signaling pathway |
GO_0071514 | Biological process | genomic imprinting |
GO_0001764 | Biological process | neuron migration |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0048871 | Biological process | multicellular organismal-level homeostasis |
GO_0007413 | Biological process | axonal fasciculation |
GO_0003016 | Biological process | respiratory system process |
GO_0008347 | Biological process | glial cell migration |
GO_0007417 | Biological process | central nervous system development |
GO_0048675 | Biological process | axon extension |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0043204 | Cellular component | perikaryon |
GO_0005813 | Cellular component | centrosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0042995 | Cellular component | cell projection |
GO_0005634 | Cellular component | nucleus |
GO_0043015 | Molecular function | gamma-tubulin binding |
GO_0003677 | Molecular function | DNA binding |
GO_1990841 | Molecular function | promoter-specific chromatin binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NDN |
Protein name | Necdin-like protein isoform 4 Necdin Necdin-like protein isoform 3 Necdin-like protein isoform 2 Necdin isoform A (Necdin-like protein isoform 1) Necdin-like protein isoform 5 Necdin isoform B |
Synonyms | |
Description | FUNCTION: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Also functions as a transcription factor and directly binds to specific guanosine-rich DNA sequences (By similarity). . |
Accessions | A0A0S2Z486 A0A0S2Z3Z2 ENST00000649030.2 X5D2Y6 A0A0S2Z3Y6 X5D982 Q99608 A0A0S2Z442 |