Name | Number of supported studies | Average coverage | |
---|---|---|---|
mast cell | 19 studies | 29% ± 7% | |
endothelial cell | 16 studies | 21% ± 5% | |
adipocyte | 6 studies | 21% ± 5% | |
fibroblast | 6 studies | 20% ± 8% | |
monocyte | 5 studies | 19% ± 3% | |
endothelial cell of lymphatic vessel | 5 studies | 23% ± 5% | |
dendritic cell | 4 studies | 25% ± 8% | |
classical monocyte | 4 studies | 20% ± 2% | |
conventional dendritic cell | 4 studies | 22% ± 5% | |
myeloid cell | 4 studies | 17% ± 1% | |
epithelial cell | 4 studies | 37% ± 12% | |
GABAergic neuron | 4 studies | 32% ± 11% | |
glutamatergic neuron | 4 studies | 45% ± 16% | |
type I pneumocyte | 4 studies | 20% ± 5% | |
erythrocyte | 4 studies | 36% ± 13% | |
macrophage | 4 studies | 24% ± 7% | |
oligodendrocyte | 4 studies | 22% ± 5% | |
astrocyte | 4 studies | 29% ± 6% | |
squamous epithelial cell | 3 studies | 32% ± 18% | |
non-classical monocyte | 3 studies | 19% ± 2% | |
mucosal invariant T cell | 3 studies | 17% ± 2% | |
lymphocyte | 3 studies | 23% ± 6% | |
T cell | 3 studies | 21% ± 7% | |
endothelial cell of vascular tree | 3 studies | 22% ± 8% | |
granulocyte | 3 studies | 25% ± 9% | |
capillary endothelial cell | 3 studies | 20% ± 4% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 17% ± 1% | |
gamma-delta T cell | 3 studies | 19% ± 1% | |
basal cell | 3 studies | 26% ± 8% | |
goblet cell | 3 studies | 39% ± 29% | |
keratinocyte | 3 studies | 19% ± 1% | |
interneuron | 3 studies | 35% ± 15% | |
neuron | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 40% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 5166.97 | 578 / 578 | 100% | 18.48 | 1155 / 1155 |
ovary | 100% | 5376.75 | 180 / 180 | 100% | 13.22 | 430 / 430 |
prostate | 100% | 3408.31 | 245 / 245 | 100% | 17.98 | 502 / 502 |
esophagus | 100% | 4308.82 | 1444 / 1445 | 100% | 23.88 | 183 / 183 |
intestine | 100% | 3207.42 | 966 / 966 | 100% | 14.93 | 526 / 527 |
breast | 100% | 3950.35 | 459 / 459 | 100% | 17.15 | 1115 / 1118 |
bladder | 100% | 3351.81 | 21 / 21 | 100% | 17.28 | 502 / 504 |
skin | 100% | 7958.30 | 1809 / 1809 | 100% | 18.11 | 470 / 472 |
uterus | 100% | 3820.31 | 170 / 170 | 100% | 19.26 | 457 / 459 |
stomach | 99% | 2425.90 | 356 / 359 | 100% | 14.19 | 286 / 286 |
thymus | 100% | 2966.24 | 651 / 653 | 99% | 17.20 | 601 / 605 |
kidney | 99% | 2111.84 | 88 / 89 | 99% | 14.24 | 889 / 901 |
adrenal gland | 100% | 5237.31 | 258 / 258 | 97% | 20.83 | 224 / 230 |
brain | 96% | 3310.68 | 2547 / 2642 | 100% | 15.70 | 704 / 705 |
pancreas | 95% | 1322.49 | 310 / 328 | 99% | 18.13 | 177 / 178 |
liver | 100% | 2631.59 | 226 / 226 | 93% | 8.11 | 379 / 406 |
adipose | 100% | 4509.65 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5599.68 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 12.13 | 29 / 29 |
spleen | 100% | 3383.97 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 20.16 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.58 | 1 / 1 |
muscle | 99% | 2675.41 | 798 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 6801.86 | 923 / 929 | 0% | 0 | 0 / 0 |
heart | 97% | 2141.88 | 834 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 10.60 | 77 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0060052 | Biological process | neurofilament cytoskeleton organization |
GO_0033157 | Biological process | regulation of intracellular protein transport |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0007059 | Biological process | chromosome segregation |
GO_0008090 | Biological process | retrograde axonal transport |
GO_0021955 | Biological process | central nervous system neuron axonogenesis |
GO_0001833 | Biological process | inner cell mass cell proliferation |
GO_1900029 | Biological process | positive regulation of ruffle assembly |
GO_0051642 | Biological process | centrosome localization |
GO_0000132 | Biological process | establishment of mitotic spindle orientation |
GO_0007020 | Biological process | microtubule nucleation |
GO_0007100 | Biological process | mitotic centrosome separation |
GO_0140650 | Biological process | radial glia-guided pyramidal neuron migration |
GO_0047496 | Biological process | vesicle transport along microtubule |
GO_0008286 | Biological process | insulin receptor signaling pathway |
GO_0021799 | Biological process | cerebral cortex radially oriented cell migration |
GO_0032418 | Biological process | lysosome localization |
GO_0051303 | Biological process | establishment of chromosome localization |
GO_0010975 | Biological process | regulation of neuron projection development |
GO_1990138 | Biological process | neuron projection extension |
GO_0016477 | Biological process | cell migration |
GO_0005874 | Cellular component | microtubule |
GO_0005813 | Cellular component | centrosome |
GO_0000776 | Cellular component | kinetochore |
GO_0043203 | Cellular component | axon hillock |
GO_0060053 | Cellular component | neurofilament cytoskeleton |
GO_0005871 | Cellular component | kinesin complex |
GO_0031252 | Cellular component | cell leading edge |
GO_0005829 | Cellular component | cytosol |
GO_0008021 | Cellular component | synaptic vesicle |
GO_1904115 | Cellular component | axon cytoplasm |
GO_0005819 | Cellular component | spindle |
GO_0048487 | Molecular function | beta-tubulin binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0043014 | Molecular function | alpha-tubulin binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NDEL1 |
Protein name | Nuclear distribution protein nudE-like 1 Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1) NudE neurodevelopment protein 1 like 1 |
Synonyms | NUDEL EOPA MITAP1 |
Description | FUNCTION: Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity). . |
Accessions | J3KRK9 ENST00000582490.5 J3QL31 J3QRD2 ENST00000580012.1 A6NIZ0 J3QSD2 ENST00000584866.1 J3KSF2 ENST00000334527.12 [Q9GZM8-1] Q9GZM8 ENST00000402554.7 [Q9GZM8-3] J3KT16 ENST00000582665.5 ENST00000581679.1 ENST00000380025.8 ENST00000580237.5 J3QRZ1 ENST00000582277.5 ENST00000582812.5 ENST00000585098.5 J3QL85 J3QLD0 |