NCOA4 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	31 studies	33% ± 11%	Explore
classical monocyte	20 studies	35% ± 14%	Explore
non-classical monocyte	19 studies	32% ± 12%	Explore
monocyte	16 studies	28% ± 10%	Explore
conventional dendritic cell	16 studies	33% ± 15%	Explore
mast cell	13 studies	23% ± 7%	Explore
erythrocyte	12 studies	53% ± 20%	Explore
myeloid cell	11 studies	31% ± 11%	Explore
platelet	9 studies	62% ± 19%	Explore
dendritic cell	9 studies	34% ± 17%	Explore
natural killer cell	9 studies	21% ± 2%	Explore
endothelial cell	8 studies	22% ± 5%	Explore
plasmacytoid dendritic cell	8 studies	27% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	20% ± 4%	Explore
basal cell	6 studies	28% ± 7%	Explore
CD4-positive, alpha-beta T cell	6 studies	20% ± 5%	Explore
hematopoietic stem cell	6 studies	39% ± 20%	Explore
alveolar macrophage	5 studies	19% ± 2%	Explore
hematopoietic precursor cell	5 studies	44% ± 11%	Explore
club cell	5 studies	27% ± 6%	Explore
respiratory goblet cell	5 studies	28% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	19% ± 3%	Explore
megakaryocyte	5 studies	71% ± 12%	Explore
CD8-positive, alpha-beta T cell	5 studies	21% ± 5%	Explore
fibroblast	5 studies	23% ± 7%	Explore
epithelial cell	4 studies	39% ± 21%	Explore
secretory cell	4 studies	29% ± 8%	Explore
regulatory T cell	4 studies	20% ± 4%	Explore
smooth muscle cell	4 studies	18% ± 2%	Explore
ciliated cell	4 studies	26% ± 10%	Explore
enterocyte	4 studies	20% ± 3%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	18% ± 3%	Explore
ionocyte	3 studies	24% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
epithelial cell of proximal tubule	3 studies	17% ± 0%	Explore
erythroblast	3 studies	40% ± 19%	Explore
common myeloid progenitor	3 studies	34% ± 16%	Explore
precursor B cell	3 studies	19% ± 2%	Explore
pro-B cell	3 studies	28% ± 6%	Explore
B cell	3 studies	17% ± 2%	Explore
serous secreting cell	3 studies	18% ± 3%	Explore
tissue-resident macrophage	3 studies	30% ± 14%	Explore
GABAergic neuron	3 studies	25% ± 4%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	59% ± 15%	Explore
neutrophil	3 studies	25% ± 4%	Explore
gamma-delta T cell	3 studies	32% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	24% ± 7%	Explore
lung	8 studies	22% ± 6%	Explore
bone marrow	5 studies	21% ± 5%	Explore
brain	5 studies	24% ± 5%	Explore
liver	4 studies	21% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	9990.98	1445 / 1445	100%	206.85	183 / 183
ovary	100%	5897.42	180 / 180	100%	139.37	430 / 430
prostate	100%	9575.02	245 / 245	100%	290.62	502 / 502
breast	100%	9176.25	459 / 459	100%	213.84	1116 / 1118
liver	100%	11101.62	226 / 226	100%	176.88	405 / 406
lung	100%	8703.28	577 / 578	100%	171.56	1154 / 1155
stomach	100%	7285.76	359 / 359	100%	162.79	285 / 286
intestine	100%	10551.62	966 / 966	99%	140.64	524 / 527
brain	99%	5033.65	2626 / 2642	100%	158.99	705 / 705
thymus	100%	7146.42	653 / 653	99%	165.64	601 / 605
bladder	100%	9422.19	21 / 21	99%	128.82	499 / 504
kidney	100%	6832.98	89 / 89	99%	203.50	890 / 901
uterus	100%	7093.99	170 / 170	98%	122.17	451 / 459
pancreas	98%	4566.62	320 / 328	99%	129.59	177 / 178
skin	100%	10065.78	1809 / 1809	96%	121.88	453 / 472
adrenal gland	100%	8389.10	258 / 258	95%	96.92	219 / 230
adipose	100%	10016.58	1204 / 1204	0%	0	0 / 0
blood vessel	100%	9057.32	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	160.24	29 / 29
muscle	100%	10934.00	803 / 803	0%	0	0 / 0
spleen	100%	12981.35	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	208.04	45 / 45
peripheral blood	100%	13571.94	926 / 929	0%	0	0 / 0
heart	97%	9546.57	831 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	112.85	76 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0008584	Biological process	male gonad development
GO_0009725	Biological process	response to hormone
GO_0071391	Biological process	cellular response to estrogen stimulus
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0006879	Biological process	intracellular iron ion homeostasis
GO_0071394	Biological process	cellular response to testosterone stimulus
GO_0006622	Biological process	protein targeting to lysosome
GO_0030520	Biological process	estrogen receptor signaling pathway
GO_0044754	Cellular component	autolysosome
GO_0005634	Cellular component	nucleus
GO_0003713	Molecular function	transcription coactivator activity

IV. Literature review

[source]

Gene name	NCOA4
Protein name	Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1) Nuclear receptor coactivator 4
Synonyms	ELE1 ARA70 RFG
Description	FUNCTION: Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. .
Accessions	ENST00000585132.5 [Q13772-1] B4DZ85 ENST00000583565.5 [Q13772-1] ENST00000578454.5 [Q13772-4] ENST00000580070.5 B4DF87 ENST00000585056.5 ENST00000581486.6 [Q13772-1] Q13772 ENST00000579039.2 [Q13772-3]

NCOA4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review