MXI1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005730Cellular componentnucleolus
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameMXI1
Protein nameMAX interactor 1 isoform 2 (MAX interactor 1, dimerization protein)
Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11)
MAX interactor 1 isoform 1
MAX interactor 1 isoform 3
Max-interacting protein 1
MAX interactor 1, dimerization protein
MAX interactor 1, dimerization protein (cDNA FLJ61042, highly similar to MAX-interacting protein 1)
SynonymsBHLHC11
DescriptionFUNCTION: Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX.

AccessionsENST00000361248.8 [P50539-4]
ENST00000650696.1 [P50539-2]
F6U3F6
A0A0S2Z3X5
F6WCI9
ENST00000460667.5
ENST00000651109.1
ENST00000651225.1
ENST00000651613.1 [P50539-2]
ENST00000652323.1
ENST00000652506.1 [P50539-2]
ENST00000652604.1 [P50539-4]
A0A494BZS3
ENST00000332674.9 [P50539-3]
ENST00000650843.1 [P50539-2]
ENST00000650810.1 [P50539-2]
B1ANN8
ENST00000651467.1 [P50539-2]
ENST00000651318.1
ENST00000650752.1
ENST00000453116.5
ENST00000239007.11 [P50539-1]
ENST00000652463.1 [P50539-2]
ENST00000650644.1 [P50539-2]
ENST00000651516.1 [P50539-2]
ENST00000652028.1 [P50539-2]
ENST00000442296.5
A0A494C0I8
A0A0S2Z3Y0
ENST00000651112.1
ENST00000650900.1 [P50539-2]
A0A0S2Z429
P50539
A0A494C1P8
Q5V9L6
ENST00000652649.1
A0A494C1C1
ENST00000652243.1
ENST00000393134.5
ENST00000484030.5
A0A494C0W2
ENST00000369612.1 [P50539-2]
ENST00000651495.1 [P50539-2]
ENST00000651866.1 [P50539-2]
ENST00000651167.1 [P50539-2]
ENST00000651004.1 [P50539-2]
ENST00000651848.1 [P50539-2]
ENST00000651557.1
ENST00000650952.1 [P50539-2]
ENST00000651811.1 [P50539-2]