Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 19 studies | 42% ± 18% | |
oligodendrocyte | 14 studies | 45% ± 17% | |
smooth muscle cell | 13 studies | 24% ± 7% | |
oligodendrocyte precursor cell | 12 studies | 42% ± 20% | |
fibroblast | 10 studies | 21% ± 8% | |
pericyte | 10 studies | 24% ± 6% | |
endothelial cell | 10 studies | 36% ± 16% | |
glutamatergic neuron | 9 studies | 39% ± 24% | |
GABAergic neuron | 8 studies | 45% ± 19% | |
erythrocyte | 7 studies | 30% ± 13% | |
interneuron | 6 studies | 43% ± 18% | |
epithelial cell | 6 studies | 31% ± 12% | |
Mueller cell | 6 studies | 48% ± 12% | |
neuron | 5 studies | 35% ± 16% | |
microglial cell | 5 studies | 26% ± 11% | |
basal cell | 5 studies | 27% ± 5% | |
ciliated cell | 5 studies | 28% ± 4% | |
retina horizontal cell | 5 studies | 30% ± 9% | |
amacrine cell | 4 studies | 31% ± 8% | |
cardiac muscle cell | 4 studies | 23% ± 3% | |
melanocyte | 4 studies | 51% ± 23% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 23% ± 5% | |
B cell | 3 studies | 24% ± 4% | |
CD4-positive, alpha-beta T cell | 3 studies | 24% ± 5% | |
GABAergic interneuron | 3 studies | 23% ± 2% | |
granule cell | 3 studies | 31% ± 10% | |
retinal ganglion cell | 3 studies | 42% ± 10% | |
retinal bipolar neuron | 3 studies | 19% ± 2% | |
retinal cone cell | 3 studies | 31% ± 5% | |
retinal rod cell | 3 studies | 25% ± 7% | |
rod bipolar cell | 3 studies | 25% ± 6% | |
ependymal cell | 3 studies | 51% ± 19% | |
macrophage | 3 studies | 23% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 7102.74 | 2641 / 2642 | 100% | 70.51 | 703 / 705 |
prostate | 100% | 5573.40 | 244 / 245 | 100% | 33.91 | 502 / 502 |
ovary | 100% | 7755.85 | 180 / 180 | 99% | 28.75 | 427 / 430 |
thymus | 100% | 5600.79 | 652 / 653 | 99% | 37.95 | 600 / 605 |
breast | 100% | 4696.28 | 459 / 459 | 98% | 30.28 | 1098 / 1118 |
skin | 98% | 4714.15 | 1769 / 1809 | 99% | 61.87 | 468 / 472 |
lung | 98% | 3264.70 | 567 / 578 | 98% | 25.34 | 1136 / 1155 |
adrenal gland | 99% | 3291.97 | 255 / 258 | 97% | 22.69 | 224 / 230 |
esophagus | 100% | 9023.96 | 1442 / 1445 | 96% | 22.65 | 176 / 183 |
kidney | 99% | 2845.84 | 88 / 89 | 97% | 49.90 | 871 / 901 |
uterus | 100% | 5544.47 | 170 / 170 | 95% | 24.56 | 438 / 459 |
intestine | 100% | 6034.61 | 964 / 966 | 95% | 20.17 | 503 / 527 |
bladder | 100% | 4517.00 | 21 / 21 | 91% | 18.70 | 460 / 504 |
pancreas | 94% | 2076.07 | 307 / 328 | 96% | 20.37 | 171 / 178 |
stomach | 97% | 3163.06 | 348 / 359 | 91% | 19.01 | 261 / 286 |
liver | 94% | 2050.66 | 212 / 226 | 93% | 17.87 | 378 / 406 |
blood vessel | 100% | 11762.88 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 69.86 | 80 / 80 |
adipose | 100% | 4166.31 | 1202 / 1204 | 0% | 0 | 0 / 0 |
muscle | 98% | 3379.43 | 785 / 803 | 0% | 0 | 0 / 0 |
heart | 96% | 3729.43 | 823 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 24.53 | 43 / 45 |
peripheral blood | 94% | 4730.20 | 876 / 929 | 0% | 0 | 0 / 0 |
spleen | 80% | 1485.78 | 193 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 45% | 4.37 | 13 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005730 | Cellular component | nucleolus |
GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
Gene name | MXI1 |
Protein name | MAX interactor 1 isoform 2 (MAX interactor 1, dimerization protein) Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11) MAX interactor 1 isoform 1 MAX interactor 1 isoform 3 Max-interacting protein 1 MAX interactor 1, dimerization protein MAX interactor 1, dimerization protein (cDNA FLJ61042, highly similar to MAX-interacting protein 1) |
Synonyms | BHLHC11 |
Description | FUNCTION: Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX. |
Accessions | ENST00000361248.8 [P50539-4] ENST00000650696.1 [P50539-2] F6U3F6 A0A0S2Z3X5 F6WCI9 ENST00000460667.5 ENST00000651109.1 ENST00000651225.1 ENST00000651613.1 [P50539-2] ENST00000652323.1 ENST00000652506.1 [P50539-2] ENST00000652604.1 [P50539-4] A0A494BZS3 ENST00000332674.9 [P50539-3] ENST00000650843.1 [P50539-2] ENST00000650810.1 [P50539-2] B1ANN8 ENST00000651467.1 [P50539-2] ENST00000651318.1 ENST00000650752.1 ENST00000453116.5 ENST00000239007.11 [P50539-1] ENST00000652463.1 [P50539-2] ENST00000650644.1 [P50539-2] ENST00000651516.1 [P50539-2] ENST00000652028.1 [P50539-2] ENST00000442296.5 A0A494C0I8 A0A0S2Z3Y0 ENST00000651112.1 ENST00000650900.1 [P50539-2] A0A0S2Z429 P50539 A0A494C1P8 Q5V9L6 ENST00000652649.1 A0A494C1C1 ENST00000652243.1 ENST00000393134.5 ENST00000484030.5 A0A494C0W2 ENST00000369612.1 [P50539-2] ENST00000651495.1 [P50539-2] ENST00000651866.1 [P50539-2] ENST00000651167.1 [P50539-2] ENST00000651004.1 [P50539-2] ENST00000651848.1 [P50539-2] ENST00000651557.1 ENST00000650952.1 [P50539-2] ENST00000651811.1 [P50539-2] |