MTMR3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042149Biological processcellular response to glucose starvation
GO_0006470Biological processprotein dephosphorylation
GO_0016236Biological processmacroautophagy
GO_0046856Biological processphosphatidylinositol dephosphorylation
GO_1904562Biological processphosphatidylinositol 5-phosphate metabolic process
GO_0010506Biological processregulation of autophagy
GO_2000785Biological processregulation of autophagosome assembly
GO_0060304Biological processregulation of phosphatidylinositol dephosphorylation
GO_0006661Biological processphosphatidylinositol biosynthetic process
GO_0016020Cellular componentmembrane
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0004438Molecular functionphosphatidylinositol-3-phosphate phosphatase activity
GO_0019903Molecular functionprotein phosphatase binding
GO_0008138Molecular functionprotein tyrosine/serine/threonine phosphatase activity
GO_0052629Molecular functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
GO_0046872Molecular functionmetal ion binding
GO_0004722Molecular functionprotein serine/threonine phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameMTMR3
Protein namePhosphatidylinositol-3-phosphate phosphatase (EC 3.1.3.48) (EC 3.1.3.64)
Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10)
Myotubularin related protein 3
SynonymshCG_41636
KIAA0371
ZFYVE10
DescriptionFUNCTION: Phosphatase that acts on lipids with a phosphoinositol headgroup . Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate . May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues . .

AccessionsENST00000323630.9
ENST00000351488.7 [Q13615-3]
ENST00000401950.7 [Q13615-1]
ENST00000406629.1 [Q13615-2]
ENST00000333027.7 [Q13615-2]
C9JLU3
ENST00000445401.5
G5E953
A7E2W2
Q13615