Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 17 studies | 31% ± 15% | |
astrocyte | 16 studies | 39% ± 18% | |
macrophage | 11 studies | 32% ± 14% | |
microglial cell | 11 studies | 34% ± 13% | |
oligodendrocyte precursor cell | 10 studies | 39% ± 16% | |
oligodendrocyte | 10 studies | 28% ± 10% | |
adipocyte | 9 studies | 31% ± 9% | |
fibroblast | 8 studies | 27% ± 9% | |
classical monocyte | 7 studies | 21% ± 5% | |
glutamatergic neuron | 7 studies | 45% ± 26% | |
GABAergic neuron | 7 studies | 47% ± 19% | |
interneuron | 6 studies | 43% ± 21% | |
pericyte | 6 studies | 32% ± 13% | |
neuron | 5 studies | 44% ± 17% | |
ciliated cell | 5 studies | 26% ± 10% | |
endothelial cell of lymphatic vessel | 5 studies | 29% ± 9% | |
smooth muscle cell | 5 studies | 26% ± 7% | |
monocyte | 5 studies | 37% ± 9% | |
granule cell | 4 studies | 28% ± 5% | |
cardiac muscle cell | 4 studies | 27% ± 2% | |
dendritic cell | 4 studies | 20% ± 2% | |
epithelial cell | 4 studies | 39% ± 21% | |
myeloid cell | 4 studies | 25% ± 4% | |
club cell | 4 studies | 29% ± 12% | |
type I pneumocyte | 4 studies | 24% ± 7% | |
type II pneumocyte | 4 studies | 23% ± 7% | |
basal cell | 4 studies | 30% ± 21% | |
GABAergic interneuron | 3 studies | 30% ± 8% | |
mast cell | 3 studies | 22% ± 5% | |
Mueller cell | 3 studies | 28% ± 8% | |
retinal cone cell | 3 studies | 26% ± 5% | |
retinal rod cell | 3 studies | 26% ± 4% | |
hepatocyte | 3 studies | 38% ± 18% | |
ependymal cell | 3 studies | 38% ± 17% | |
T cell | 3 studies | 20% ± 3% | |
alveolar macrophage | 3 studies | 42% ± 15% | |
respiratory goblet cell | 3 studies | 35% ± 19% | |
lymphocyte | 3 studies | 26% ± 9% | |
goblet cell | 3 studies | 38% ± 32% | |
mural cell | 3 studies | 30% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 1011.86 | 245 / 245 | 100% | 3.94 | 502 / 502 |
brain | 100% | 935.83 | 2640 / 2642 | 100% | 5.43 | 705 / 705 |
thymus | 100% | 1010.47 | 653 / 653 | 98% | 3.86 | 594 / 605 |
breast | 100% | 843.65 | 459 / 459 | 97% | 2.96 | 1082 / 1118 |
pancreas | 99% | 440.64 | 325 / 328 | 96% | 2.80 | 171 / 178 |
esophagus | 100% | 835.74 | 1445 / 1445 | 95% | 2.32 | 174 / 183 |
uterus | 100% | 1044.21 | 170 / 170 | 94% | 2.55 | 432 / 459 |
kidney | 100% | 733.79 | 89 / 89 | 94% | 2.41 | 847 / 901 |
lung | 100% | 976.29 | 578 / 578 | 94% | 2.61 | 1085 / 1155 |
skin | 100% | 955.79 | 1808 / 1809 | 94% | 2.44 | 443 / 472 |
bladder | 100% | 831.14 | 21 / 21 | 93% | 2.35 | 471 / 504 |
intestine | 100% | 897.09 | 966 / 966 | 91% | 1.80 | 482 / 527 |
stomach | 100% | 687.10 | 359 / 359 | 90% | 1.78 | 257 / 286 |
ovary | 100% | 1103.78 | 180 / 180 | 84% | 1.94 | 361 / 430 |
adrenal gland | 100% | 974.92 | 258 / 258 | 81% | 2.15 | 186 / 230 |
liver | 98% | 316.73 | 222 / 226 | 50% | 0.92 | 201 / 406 |
adipose | 100% | 792.91 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1302.23 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.36 | 1 / 1 |
muscle | 100% | 767.82 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 665.01 | 1330 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 1561.49 | 922 / 929 | 0% | 0 | 0 / 0 |
heart | 99% | 525.14 | 854 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 3.32 | 79 / 80 |
tonsil | 0% | 0 | 0 / 0 | 98% | 2.88 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 97% | 1.80 | 28 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0042149 | Biological process | cellular response to glucose starvation |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0016236 | Biological process | macroautophagy |
GO_0046856 | Biological process | phosphatidylinositol dephosphorylation |
GO_1904562 | Biological process | phosphatidylinositol 5-phosphate metabolic process |
GO_0010506 | Biological process | regulation of autophagy |
GO_2000785 | Biological process | regulation of autophagosome assembly |
GO_0060304 | Biological process | regulation of phosphatidylinositol dephosphorylation |
GO_0006661 | Biological process | phosphatidylinositol biosynthetic process |
GO_0016020 | Cellular component | membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0004438 | Molecular function | phosphatidylinositol-3-phosphate phosphatase activity |
GO_0019903 | Molecular function | protein phosphatase binding |
GO_0008138 | Molecular function | protein tyrosine/serine/threonine phosphatase activity |
GO_0052629 | Molecular function | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
GO_0005515 | Molecular function | protein binding |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | MTMR3 |
Protein name | Phosphatidylinositol-3-phosphate phosphatase (EC 3.1.3.48) (EC 3.1.3.64) Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10) Myotubularin related protein 3 |
Synonyms | hCG_41636 KIAA0371 ZFYVE10 |
Description | FUNCTION: Phosphatase that acts on lipids with a phosphoinositol headgroup . Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate . May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues . . |
Accessions | ENST00000323630.9 ENST00000351488.7 [Q13615-3] ENST00000401950.7 [Q13615-1] ENST00000406629.1 [Q13615-2] ENST00000333027.7 [Q13615-2] C9JLU3 ENST00000445401.5 G5E953 A7E2W2 Q13615 |