Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 19 studies | 54% ± 20% | |
endothelial cell | 9 studies | 22% ± 8% | |
fibroblast | 9 studies | 21% ± 7% | |
cardiac muscle cell | 6 studies | 40% ± 8% | |
basal cell | 6 studies | 22% ± 6% | |
connective tissue cell | 4 studies | 19% ± 2% | |
retinal rod cell | 4 studies | 30% ± 8% | |
luminal hormone-sensing cell of mammary gland | 4 studies | 21% ± 4% | |
astrocyte | 4 studies | 19% ± 4% | |
deuterosomal cell | 3 studies | 26% ± 1% | |
myofibroblast cell | 3 studies | 25% ± 11% | |
epithelial cell | 3 studies | 28% ± 6% | |
retinal cone cell | 3 studies | 39% ± 11% | |
GABAergic neuron | 3 studies | 27% ± 10% | |
glutamatergic neuron | 3 studies | 42% ± 5% | |
ependymal cell | 3 studies | 43% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1108.24 | 2629 / 2642 | 100% | 26.06 | 703 / 705 |
ovary | 100% | 711.87 | 180 / 180 | 99% | 47.86 | 426 / 430 |
breast | 97% | 565.80 | 445 / 459 | 97% | 26.33 | 1089 / 1118 |
uterus | 98% | 570.90 | 167 / 170 | 95% | 35.82 | 436 / 459 |
lung | 98% | 732.53 | 566 / 578 | 90% | 28.69 | 1040 / 1155 |
thymus | 98% | 612.93 | 641 / 653 | 87% | 10.05 | 526 / 605 |
kidney | 100% | 701.27 | 89 / 89 | 82% | 11.77 | 739 / 901 |
bladder | 100% | 436.00 | 21 / 21 | 81% | 17.22 | 407 / 504 |
skin | 95% | 397.17 | 1715 / 1809 | 81% | 12.03 | 382 / 472 |
adrenal gland | 93% | 343.08 | 239 / 258 | 77% | 9.28 | 178 / 230 |
prostate | 81% | 297.38 | 198 / 245 | 71% | 7.55 | 357 / 502 |
esophagus | 78% | 437.28 | 1123 / 1445 | 64% | 18.62 | 118 / 183 |
intestine | 81% | 480.36 | 785 / 966 | 51% | 7.09 | 267 / 527 |
pancreas | 28% | 71.64 | 92 / 328 | 87% | 13.81 | 155 / 178 |
stomach | 55% | 277.43 | 199 / 359 | 45% | 6.61 | 128 / 286 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.49 | 1 / 1 |
heart | 99% | 4513.30 | 851 / 861 | 0% | 0 | 0 / 0 |
muscle | 98% | 1487.15 | 787 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 40.47 | 44 / 45 |
adipose | 97% | 514.14 | 1166 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 96% | 467.43 | 1288 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 24% | 2.16 | 19 / 80 |
liver | 0% | 1.99 | 1 / 226 | 10% | 1.10 | 42 / 406 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.60 | 3 / 29 |
spleen | 9% | 22.33 | 22 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 3% | 14.36 | 32 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006351 | Biological process | DNA-templated transcription |
GO_0002318 | Biological process | myeloid progenitor cell differentiation |
GO_1902806 | Biological process | regulation of cell cycle G1/S phase transition |
GO_1901796 | Biological process | regulation of signal transduction by p53 class mediator |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0005929 | Cellular component | cilium |
GO_0036064 | Cellular component | ciliary basal body |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MLF1 |
Protein name | Myeloid leukemia factor 1 (Myeloid leukemia factor 1, isoform CRA_c) Myeloid leukemia factor 1 variant 2 Myeloid leukemia factor 1 Myeloid leukemia factor 1 isoform 5 Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1) Myeloid leukemia factor 1 isoform 1 (Myeloid leukemia factor 1, isoform CRA_a) |
Synonyms | hCG_16019 |
Description | FUNCTION: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. . |
Accessions | ENST00000469452.5 [P58340-2] A0A0S2Z4U8 ENST00000650753.1 A0A494C1S3 A0A494C1P6 F8WEY0 ENST00000618075.4 [P58340-2] ENST00000650750.1 A0A494C175 ENST00000487838.5 ENST00000359117.9 [P58340-5] A0A0S2Z4B4 ENST00000651874.1 [P58340-5] C9JNE5 ENST00000651984.1 [P58340-5] ENST00000466246.7 A0A499FJ64 ENST00000478894.7 [P58340-4] ENST00000495452.5 A0A494C127 ENST00000652045.1 ENST00000482628.5 [P58340-5] ENST00000619577.5 P58340 C9K0D4 ENST00000651984.1 ENST00000477042.6 [P58340-4] ENST00000498592.6 ENST00000484955.5 [P58340-5] A0A0S2Z4A4 ENST00000471745.5 [P58340-4] F8VXT4 ENST00000355893.11 [P58340-1] ENST00000491767.6 Q2TLE4 |