Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 35 studies | 35% ± 15% | |
| pericyte | 34 studies | 33% ± 13% | |
| smooth muscle cell | 20 studies | 29% ± 11% | |
| macrophage | 16 studies | 30% ± 15% | |
| fibroblast | 15 studies | 23% ± 5% | |
| astrocyte | 14 studies | 40% ± 21% | |
| endothelial cell of lymphatic vessel | 12 studies | 24% ± 7% | |
| ciliated cell | 12 studies | 31% ± 11% | |
| endothelial cell of vascular tree | 12 studies | 30% ± 13% | |
| type I pneumocyte | 11 studies | 54% ± 13% | |
| oligodendrocyte precursor cell | 11 studies | 40% ± 20% | |
| epithelial cell | 11 studies | 33% ± 21% | |
| type II pneumocyte | 9 studies | 31% ± 10% | |
| platelet | 9 studies | 34% ± 12% | |
| goblet cell | 9 studies | 38% ± 11% | |
| plasmacytoid dendritic cell | 9 studies | 23% ± 6% | |
| glutamatergic neuron | 8 studies | 35% ± 21% | |
| kidney loop of Henle epithelial cell | 8 studies | 30% ± 14% | |
| endothelial cell of artery | 8 studies | 29% ± 13% | |
| capillary endothelial cell | 8 studies | 41% ± 16% | |
| dendritic cell | 8 studies | 44% ± 13% | |
| adipocyte | 8 studies | 35% ± 8% | |
| basal cell | 7 studies | 26% ± 18% | |
| GABAergic neuron | 7 studies | 38% ± 17% | |
| myeloid cell | 7 studies | 31% ± 17% | |
| vein endothelial cell | 7 studies | 32% ± 13% | |
| non-classical monocyte | 6 studies | 24% ± 5% | |
| microglial cell | 6 studies | 23% ± 10% | |
| connective tissue cell | 5 studies | 27% ± 7% | |
| hematopoietic stem cell | 5 studies | 25% ± 13% | |
| retinal ganglion cell | 4 studies | 52% ± 19% | |
| myofibroblast cell | 4 studies | 25% ± 5% | |
| hepatocyte | 4 studies | 40% ± 26% | |
| ionocyte | 3 studies | 31% ± 7% | |
| classical monocyte | 3 studies | 29% ± 16% | |
| hematopoietic precursor cell | 3 studies | 22% ± 8% | |
| abnormal cell | 3 studies | 38% ± 20% | |
| extravillous trophoblast | 3 studies | 23% ± 8% | |
| squamous epithelial cell | 3 studies | 37% ± 16% | |
| enterocyte | 3 studies | 29% ± 3% | |
| muscle cell | 3 studies | 34% ± 10% | |
| brush cell | 3 studies | 28% ± 10% | |
| enteroendocrine cell | 3 studies | 26% ± 3% | |
| interneuron | 3 studies | 62% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 13942.33 | 2624 / 2642 | 99% | 42.57 | 698 / 705 |
| kidney | 100% | 13432.43 | 89 / 89 | 98% | 73.96 | 885 / 901 |
| intestine | 100% | 11694.81 | 964 / 966 | 98% | 45.02 | 516 / 527 |
| lung | 100% | 12611.72 | 576 / 578 | 86% | 38.30 | 994 / 1155 |
| esophagus | 100% | 13719.80 | 1443 / 1445 | 86% | 31.53 | 157 / 183 |
| liver | 100% | 11495.98 | 226 / 226 | 85% | 32.21 | 345 / 406 |
| breast | 100% | 19129.96 | 458 / 459 | 83% | 25.02 | 928 / 1118 |
| prostate | 95% | 5625.89 | 232 / 245 | 87% | 18.97 | 438 / 502 |
| stomach | 89% | 4291.21 | 318 / 359 | 92% | 37.03 | 262 / 286 |
| skin | 99% | 8027.92 | 1787 / 1809 | 61% | 19.31 | 290 / 472 |
| uterus | 90% | 3967.28 | 153 / 170 | 69% | 16.44 | 315 / 459 |
| bladder | 100% | 8605.14 | 21 / 21 | 57% | 18.72 | 285 / 504 |
| thymus | 90% | 4099.70 | 589 / 653 | 51% | 6.88 | 310 / 605 |
| adrenal gland | 75% | 2857.53 | 193 / 258 | 43% | 7.39 | 99 / 230 |
| adipose | 100% | 24799.65 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 9345.99 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 7971.08 | 240 / 241 | 0% | 0 | 0 / 0 |
| heart | 100% | 8764.97 | 857 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 5% | 161.61 | 17 / 328 | 93% | 59.19 | 165 / 178 |
| muscle | 97% | 5326.01 | 782 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 21.70 | 24 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 64% | 16.09 | 29 / 45 |
| ovary | 10% | 508.97 | 18 / 180 | 54% | 10.75 | 232 / 430 |
| eye | 0% | 0 | 0 / 0 | 40% | 8.45 | 32 / 80 |
| peripheral blood | 21% | 2509.78 | 197 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0052651 | Biological process | monoacylglycerol catabolic process |
| GO_0009966 | Biological process | regulation of signal transduction |
| GO_0006954 | Biological process | inflammatory response |
| GO_0051930 | Biological process | regulation of sensory perception of pain |
| GO_0050727 | Biological process | regulation of inflammatory response |
| GO_0019433 | Biological process | triglyceride catabolic process |
| GO_0006633 | Biological process | fatty acid biosynthetic process |
| GO_0046464 | Biological process | acylglycerol catabolic process |
| GO_2000124 | Biological process | regulation of endocannabinoid signaling pathway |
| GO_0006629 | Biological process | lipid metabolic process |
| GO_0019369 | Biological process | arachidonic acid metabolic process |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0004622 | Molecular function | lysophospholipase activity |
| GO_0047372 | Molecular function | acylglycerol lipase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MGLL |
| Protein name | Monoglyceride lipase Monoglyceride lipase (MGL) (EC 3.1.1.23) (HU-K5) (Lysophospholipase homolog) (Lysophospholipase-like) (Monoacylglycerol lipase) (MAGL) Monoacylglycerol lipase isoform 2 |
| Synonyms | |
| Description | FUNCTION: Converts monoacylglycerides to free fatty acids and glycerol . Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain . Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth . . |
| Accessions | ENST00000496306.5 B2ZGL7 C9JAM4 ENST00000494830.1 ENST00000648300.1 H7C5K5 H7C4E0 Q99685 ENST00000398104.6 [Q99685-1] ENST00000487473.6 ENST00000453507.7 [Q99685-2] A0A0C4DFN3 ENST00000265052.10 A0A3B3ITT3 |