Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 35 studies | 35% ± 15% | |
pericyte | 34 studies | 33% ± 13% | |
smooth muscle cell | 20 studies | 29% ± 11% | |
macrophage | 16 studies | 30% ± 15% | |
fibroblast | 15 studies | 23% ± 5% | |
astrocyte | 14 studies | 40% ± 21% | |
endothelial cell of lymphatic vessel | 12 studies | 24% ± 7% | |
ciliated cell | 12 studies | 31% ± 11% | |
endothelial cell of vascular tree | 12 studies | 30% ± 13% | |
type I pneumocyte | 11 studies | 54% ± 13% | |
oligodendrocyte precursor cell | 11 studies | 40% ± 20% | |
epithelial cell | 11 studies | 33% ± 21% | |
type II pneumocyte | 9 studies | 31% ± 10% | |
platelet | 9 studies | 34% ± 12% | |
goblet cell | 9 studies | 38% ± 11% | |
plasmacytoid dendritic cell | 9 studies | 23% ± 6% | |
glutamatergic neuron | 8 studies | 35% ± 21% | |
kidney loop of Henle epithelial cell | 8 studies | 30% ± 14% | |
endothelial cell of artery | 8 studies | 29% ± 13% | |
capillary endothelial cell | 8 studies | 41% ± 16% | |
dendritic cell | 8 studies | 44% ± 13% | |
adipocyte | 8 studies | 35% ± 8% | |
basal cell | 7 studies | 26% ± 18% | |
GABAergic neuron | 7 studies | 38% ± 17% | |
myeloid cell | 7 studies | 31% ± 17% | |
vein endothelial cell | 7 studies | 32% ± 13% | |
non-classical monocyte | 6 studies | 24% ± 5% | |
microglial cell | 6 studies | 23% ± 10% | |
connective tissue cell | 5 studies | 27% ± 7% | |
hematopoietic stem cell | 5 studies | 25% ± 13% | |
retinal ganglion cell | 4 studies | 52% ± 19% | |
myofibroblast cell | 4 studies | 25% ± 5% | |
hepatocyte | 4 studies | 40% ± 26% | |
ionocyte | 3 studies | 31% ± 7% | |
classical monocyte | 3 studies | 29% ± 16% | |
hematopoietic precursor cell | 3 studies | 22% ± 8% | |
abnormal cell | 3 studies | 38% ± 20% | |
extravillous trophoblast | 3 studies | 23% ± 8% | |
squamous epithelial cell | 3 studies | 37% ± 16% | |
enterocyte | 3 studies | 29% ± 3% | |
muscle cell | 3 studies | 34% ± 10% | |
brush cell | 3 studies | 28% ± 10% | |
enteroendocrine cell | 3 studies | 26% ± 3% | |
interneuron | 3 studies | 62% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 13942.33 | 2624 / 2642 | 99% | 42.57 | 698 / 705 |
kidney | 100% | 13432.43 | 89 / 89 | 98% | 73.96 | 885 / 901 |
intestine | 100% | 11694.81 | 964 / 966 | 98% | 45.02 | 516 / 527 |
lung | 100% | 12611.72 | 576 / 578 | 86% | 38.30 | 994 / 1155 |
esophagus | 100% | 13719.80 | 1443 / 1445 | 86% | 31.53 | 157 / 183 |
liver | 100% | 11495.98 | 226 / 226 | 85% | 32.21 | 345 / 406 |
breast | 100% | 19129.96 | 458 / 459 | 83% | 25.02 | 928 / 1118 |
prostate | 95% | 5625.89 | 232 / 245 | 87% | 18.97 | 438 / 502 |
stomach | 89% | 4291.21 | 318 / 359 | 92% | 37.03 | 262 / 286 |
skin | 99% | 8027.92 | 1787 / 1809 | 61% | 19.31 | 290 / 472 |
uterus | 90% | 3967.28 | 153 / 170 | 69% | 16.44 | 315 / 459 |
bladder | 100% | 8605.14 | 21 / 21 | 57% | 18.72 | 285 / 504 |
thymus | 90% | 4099.70 | 589 / 653 | 51% | 6.88 | 310 / 605 |
adrenal gland | 75% | 2857.53 | 193 / 258 | 43% | 7.39 | 99 / 230 |
adipose | 100% | 24799.65 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 9345.99 | 1331 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 7971.08 | 240 / 241 | 0% | 0 | 0 / 0 |
heart | 100% | 8764.97 | 857 / 861 | 0% | 0 | 0 / 0 |
pancreas | 5% | 161.61 | 17 / 328 | 93% | 59.19 | 165 / 178 |
muscle | 97% | 5326.01 | 782 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 83% | 21.70 | 24 / 29 |
tonsil | 0% | 0 | 0 / 0 | 64% | 16.09 | 29 / 45 |
ovary | 10% | 508.97 | 18 / 180 | 54% | 10.75 | 232 / 430 |
eye | 0% | 0 | 0 / 0 | 40% | 8.45 | 32 / 80 |
peripheral blood | 21% | 2509.78 | 197 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0052651 | Biological process | monoacylglycerol catabolic process |
GO_0009966 | Biological process | regulation of signal transduction |
GO_0006954 | Biological process | inflammatory response |
GO_0051930 | Biological process | regulation of sensory perception of pain |
GO_0050727 | Biological process | regulation of inflammatory response |
GO_0019433 | Biological process | triglyceride catabolic process |
GO_0006633 | Biological process | fatty acid biosynthetic process |
GO_0046464 | Biological process | acylglycerol catabolic process |
GO_2000124 | Biological process | regulation of endocannabinoid signaling pathway |
GO_0006629 | Biological process | lipid metabolic process |
GO_0019369 | Biological process | arachidonic acid metabolic process |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005829 | Cellular component | cytosol |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0004622 | Molecular function | lysophospholipase activity |
GO_0047372 | Molecular function | acylglycerol lipase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | MGLL |
Protein name | Monoglyceride lipase Monoglyceride lipase (MGL) (EC 3.1.1.23) (HU-K5) (Lysophospholipase homolog) (Lysophospholipase-like) (Monoacylglycerol lipase) (MAGL) Monoacylglycerol lipase isoform 2 |
Synonyms | |
Description | FUNCTION: Converts monoacylglycerides to free fatty acids and glycerol . Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain . Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth . . |
Accessions | ENST00000496306.5 B2ZGL7 C9JAM4 ENST00000494830.1 ENST00000648300.1 H7C5K5 H7C4E0 Q99685 ENST00000398104.6 [Q99685-1] ENST00000487473.6 ENST00000453507.7 [Q99685-2] A0A0C4DFN3 ENST00000265052.10 A0A3B3ITT3 |