Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 14 studies | 25% ± 11% | |
astrocyte | 11 studies | 33% ± 15% | |
oligodendrocyte | 11 studies | 35% ± 11% | |
microglial cell | 10 studies | 26% ± 9% | |
oligodendrocyte precursor cell | 10 studies | 31% ± 13% | |
glutamatergic neuron | 9 studies | 39% ± 25% | |
GABAergic neuron | 8 studies | 38% ± 20% | |
macrophage | 8 studies | 25% ± 6% | |
fibroblast | 7 studies | 26% ± 7% | |
neuron | 6 studies | 32% ± 17% | |
interneuron | 6 studies | 39% ± 24% | |
epithelial cell | 6 studies | 26% ± 8% | |
adipocyte | 5 studies | 23% ± 4% | |
endothelial cell of lymphatic vessel | 5 studies | 28% ± 9% | |
granule cell | 4 studies | 24% ± 5% | |
cardiac muscle cell | 4 studies | 22% ± 2% | |
lymphocyte | 4 studies | 26% ± 7% | |
mast cell | 4 studies | 24% ± 3% | |
monocyte | 4 studies | 17% ± 1% | |
pericyte | 4 studies | 29% ± 17% | |
smooth muscle cell | 4 studies | 18% ± 2% | |
GABAergic interneuron | 3 studies | 22% ± 5% | |
B cell | 3 studies | 21% ± 3% | |
myeloid cell | 3 studies | 21% ± 3% | |
CD8-positive, alpha-beta T cell | 3 studies | 15% ± 0% | |
natural killer cell | 3 studies | 27% ± 13% | |
basal cell | 3 studies | 21% ± 7% | |
alveolar macrophage | 3 studies | 22% ± 5% | |
transit amplifying cell | 3 studies | 24% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2335.14 | 1445 / 1445 | 100% | 12.88 | 183 / 183 |
prostate | 100% | 2731.94 | 245 / 245 | 100% | 10.89 | 501 / 502 |
brain | 100% | 2017.90 | 2635 / 2642 | 99% | 8.34 | 700 / 705 |
uterus | 100% | 3451.16 | 170 / 170 | 99% | 11.50 | 454 / 459 |
ovary | 100% | 3987.78 | 180 / 180 | 99% | 8.05 | 425 / 430 |
lung | 100% | 2130.43 | 577 / 578 | 99% | 9.30 | 1143 / 1155 |
breast | 100% | 2665.19 | 459 / 459 | 99% | 12.24 | 1102 / 1118 |
thymus | 100% | 2905.31 | 653 / 653 | 99% | 9.23 | 596 / 605 |
bladder | 100% | 2771.38 | 21 / 21 | 98% | 7.70 | 494 / 504 |
pancreas | 100% | 1640.93 | 327 / 328 | 98% | 7.38 | 175 / 178 |
stomach | 100% | 1966.60 | 359 / 359 | 96% | 8.46 | 275 / 286 |
intestine | 100% | 2547.68 | 966 / 966 | 96% | 7.27 | 504 / 527 |
skin | 100% | 2661.59 | 1809 / 1809 | 95% | 9.11 | 447 / 472 |
kidney | 100% | 1579.25 | 89 / 89 | 94% | 6.70 | 846 / 901 |
adrenal gland | 100% | 2616.58 | 258 / 258 | 91% | 5.48 | 210 / 230 |
liver | 100% | 1090.02 | 226 / 226 | 70% | 3.05 | 283 / 406 |
adipose | 100% | 2345.07 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2582.80 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 7.53 | 29 / 29 |
muscle | 100% | 1717.89 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3058.28 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 13.34 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.00 | 1 / 1 |
heart | 98% | 1631.79 | 845 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 88% | 5.14 | 70 / 80 |
peripheral blood | 68% | 1305.87 | 631 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0001708 | Biological process | cell fate specification |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0071339 | Cellular component | MLL1 complex |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
Gene name | MGA |
Protein name | MAX dimerization protein MGA MAX gene-associated protein (MAX dimerization protein 5) |
Synonyms | KIAA0518 MAD5 |
Description | FUNCTION: Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor (By similarity). . |
Accessions | ENST00000703843.1 A0A994J4J1 H3BU53 H3BP52 ENST00000570161.6 ENST00000566718.6 Q8IWI9 ENST00000219905.13 [Q8IWI9-4] A0A8C8P5L8 ENST00000703841.1 A0A994J6L2 A0A994J443 ENST00000564190.1 ENST00000566586.6 [Q8IWI9-3] ENST00000703842.1 |