Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 18 studies | 39% ± 20% | |
| endothelial cell | 18 studies | 30% ± 13% | |
| microglial cell | 13 studies | 31% ± 13% | |
| oligodendrocyte precursor cell | 12 studies | 32% ± 14% | |
| oligodendrocyte | 11 studies | 33% ± 13% | |
| fibroblast | 10 studies | 29% ± 11% | |
| glutamatergic neuron | 9 studies | 43% ± 28% | |
| adipocyte | 9 studies | 36% ± 9% | |
| GABAergic neuron | 8 studies | 43% ± 22% | |
| macrophage | 7 studies | 31% ± 8% | |
| epithelial cell | 7 studies | 31% ± 14% | |
| ciliated cell | 7 studies | 32% ± 15% | |
| smooth muscle cell | 6 studies | 26% ± 5% | |
| endothelial cell of lymphatic vessel | 5 studies | 30% ± 5% | |
| pericyte | 5 studies | 25% ± 6% | |
| type I pneumocyte | 5 studies | 33% ± 6% | |
| type II pneumocyte | 5 studies | 30% ± 5% | |
| interneuron | 5 studies | 46% ± 26% | |
| neuron | 4 studies | 39% ± 16% | |
| cardiac muscle cell | 4 studies | 30% ± 1% | |
| Mueller cell | 4 studies | 29% ± 14% | |
| T cell | 4 studies | 21% ± 3% | |
| club cell | 4 studies | 28% ± 8% | |
| basal cell | 4 studies | 33% ± 18% | |
| GABAergic interneuron | 3 studies | 23% ± 2% | |
| plasma cell | 3 studies | 23% ± 8% | |
| amacrine cell | 3 studies | 23% ± 10% | |
| retinal cone cell | 3 studies | 26% ± 11% | |
| retinal rod cell | 3 studies | 22% ± 4% | |
| myeloid cell | 3 studies | 22% ± 2% | |
| hepatocyte | 3 studies | 39% ± 9% | |
| connective tissue cell | 3 studies | 20% ± 3% | |
| ependymal cell | 3 studies | 49% ± 10% | |
| alveolar macrophage | 3 studies | 25% ± 5% | |
| monocyte | 3 studies | 23% ± 6% | |
| respiratory goblet cell | 3 studies | 34% ± 10% | |
| lymphocyte | 3 studies | 25% ± 8% | |
| goblet cell | 3 studies | 33% ± 20% | |
| transit amplifying cell | 3 studies | 38% ± 30% | |
| mesothelial cell | 3 studies | 37% ± 6% | |
| granule cell | 3 studies | 29% ± 12% | |
| mast cell | 3 studies | 22% ± 1% | |
| mucus secreting cell | 3 studies | 25% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 547.84 | 1445 / 1445 | 100% | 6.10 | 183 / 183 |
| prostate | 100% | 661.68 | 245 / 245 | 100% | 5.61 | 502 / 502 |
| thymus | 100% | 719.16 | 653 / 653 | 100% | 6.01 | 605 / 605 |
| breast | 100% | 655.80 | 459 / 459 | 100% | 7.32 | 1117 / 1118 |
| uterus | 100% | 624.60 | 170 / 170 | 100% | 4.58 | 458 / 459 |
| brain | 100% | 549.32 | 2634 / 2642 | 100% | 4.63 | 705 / 705 |
| kidney | 100% | 593.67 | 89 / 89 | 100% | 5.99 | 898 / 901 |
| stomach | 100% | 445.03 | 359 / 359 | 100% | 5.45 | 285 / 286 |
| intestine | 100% | 661.11 | 966 / 966 | 100% | 5.50 | 525 / 527 |
| ovary | 100% | 639.44 | 180 / 180 | 100% | 4.08 | 428 / 430 |
| lung | 99% | 528.57 | 575 / 578 | 100% | 5.20 | 1155 / 1155 |
| bladder | 100% | 667.10 | 21 / 21 | 99% | 4.23 | 501 / 504 |
| liver | 100% | 483.41 | 226 / 226 | 99% | 3.74 | 403 / 406 |
| adrenal gland | 100% | 960.84 | 258 / 258 | 99% | 4.56 | 228 / 230 |
| pancreas | 99% | 369.38 | 326 / 328 | 99% | 4.51 | 177 / 178 |
| skin | 100% | 779.49 | 1809 / 1809 | 93% | 4.63 | 438 / 472 |
| adipose | 100% | 606.38 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 661.12 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 4.42 | 29 / 29 |
| spleen | 100% | 492.03 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 5.04 | 45 / 45 |
| muscle | 100% | 620.37 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 488.55 | 838 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 60% | 1.77 | 48 / 80 |
| peripheral blood | 47% | 360.11 | 435 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0070475 | Biological process | rRNA base methylation |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0071424 | Molecular function | rRNA (cytosine-N4-)-methyltransferase activity |
| Gene name | METTL15 |
| Protein name | 12S rRNA N4-methylcytidine (m4C) methyltransferase (12S rRNA m4C methyltransferase) (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) (Methyltransferase-like protein 15) Methyltransferase like 15 |
| Synonyms | METT5D1 |
| Description | FUNCTION: N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA . Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits . . |
| Accessions | F8WD83 ENST00000634721.1 ENST00000407364.8 [A6NJ78-1] ENST00000532947.2 A6NJ78 ENST00000437814.1 [A6NJ78-3] ENST00000303459.10 [A6NJ78-2] A0A0U1RR64 ENST00000634762.1 A0A0U1RR76 ENST00000634973.1 B5MC64 ENST00000403099.5 ENST00000451385.6 A0A0U1RRD2 ENST00000634627.1 A0A0U1RRF2 ENST00000406787.7 [A6NJ78-4] |