MATK report

II. Expression across tissues

III. Associated gene sets

GO_0008284Biological processpositive regulation of cell population proliferation
GO_0006468Biological processprotein phosphorylation
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0004713Molecular functionprotein tyrosine kinase activity
GO_0004715Molecular functionnon-membrane spanning protein tyrosine kinase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameMATK
Protein nameMegakaryocyte-associated tyrosine kinase
Tyrosine-protein kinase (EC 2.7.10.2)
non-specific protein-tyrosine kinase (EC 2.7.10.2)
Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)
SynonymsCTK
HYL
hCG_23522
DescriptionFUNCTION: Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. .

AccessionsENST00000591059.1
K7EKC4
ENST00000590980.1
ENST00000590493.5
K7EQY5
ENST00000619596.4 [P42679-2]
ENST00000310132.11 [P42679-1]
K7ES68
ENST00000395045.6 [P42679-2]
F1T0G6
K7EPP2
ENST00000590849.1
ENST00000590028.5
K7EQV3
K7EKS5
ENST00000585778.5
K7ERY4
P42679
ENST00000587180.1
K7ENL8
ENST00000395040.6 [P42679-3]
ENST00000588983.5