Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 13 studies | 41% ± 18% | |
| fibroblast | 11 studies | 26% ± 6% | |
| endothelial cell | 11 studies | 30% ± 20% | |
| mast cell | 11 studies | 32% ± 11% | |
| endothelial cell of lymphatic vessel | 9 studies | 29% ± 9% | |
| microglial cell | 8 studies | 42% ± 15% | |
| naive B cell | 7 studies | 20% ± 2% | |
| adipocyte | 7 studies | 36% ± 8% | |
| B cell | 7 studies | 22% ± 7% | |
| GABAergic neuron | 6 studies | 27% ± 10% | |
| retinal ganglion cell | 6 studies | 39% ± 12% | |
| retina horizontal cell | 5 studies | 48% ± 11% | |
| retinal cone cell | 5 studies | 21% ± 7% | |
| cardiac muscle cell | 5 studies | 43% ± 10% | |
| Mueller cell | 5 studies | 44% ± 15% | |
| mesothelial cell | 4 studies | 25% ± 9% | |
| vein endothelial cell | 4 studies | 28% ± 13% | |
| retinal rod cell | 4 studies | 30% ± 7% | |
| glutamatergic neuron | 4 studies | 32% ± 11% | |
| erythrocyte | 4 studies | 53% ± 20% | |
| amacrine cell | 3 studies | 37% ± 19% | |
| GABAergic amacrine cell | 3 studies | 28% ± 4% | |
| OFF-bipolar cell | 3 studies | 28% ± 6% | |
| ON-bipolar cell | 3 studies | 21% ± 7% | |
| glycinergic amacrine cell | 3 studies | 31% ± 11% | |
| adventitial cell | 3 studies | 26% ± 5% | |
| interneuron | 3 studies | 38% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 658.59 | 964 / 966 | 97% | 10.60 | 511 / 527 |
| breast | 100% | 685.13 | 457 / 459 | 86% | 6.01 | 966 / 1118 |
| brain | 85% | 364.44 | 2255 / 2642 | 99% | 14.66 | 700 / 705 |
| adrenal gland | 100% | 696.06 | 258 / 258 | 84% | 7.76 | 193 / 230 |
| lung | 99% | 608.83 | 571 / 578 | 79% | 4.17 | 907 / 1155 |
| skin | 97% | 1148.36 | 1753 / 1809 | 75% | 5.58 | 353 / 472 |
| stomach | 72% | 276.00 | 257 / 359 | 95% | 8.53 | 272 / 286 |
| pancreas | 65% | 157.26 | 213 / 328 | 94% | 9.31 | 168 / 178 |
| uterus | 95% | 422.75 | 161 / 170 | 62% | 3.16 | 283 / 459 |
| esophagus | 80% | 302.16 | 1162 / 1445 | 75% | 5.45 | 138 / 183 |
| bladder | 86% | 463.95 | 18 / 21 | 64% | 4.44 | 323 / 504 |
| thymus | 95% | 423.11 | 623 / 653 | 22% | 0.72 | 133 / 605 |
| ovary | 80% | 255.24 | 144 / 180 | 34% | 1.14 | 145 / 430 |
| prostate | 57% | 151.73 | 139 / 245 | 51% | 1.85 | 256 / 502 |
| spleen | 100% | 343.38 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 888.66 | 1201 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 9.32 | 28 / 29 |
| heart | 97% | 1139.92 | 831 / 861 | 0% | 0 | 0 / 0 |
| kidney | 46% | 147.91 | 41 / 89 | 47% | 1.80 | 426 / 901 |
| peripheral blood | 93% | 421.46 | 860 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 87% | 397.41 | 1158 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 84% | 297.02 | 674 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 71% | 3.19 | 32 / 45 |
| liver | 10% | 25.25 | 22 / 226 | 31% | 1.55 | 124 / 406 |
| eye | 0% | 0 | 0 / 0 | 24% | 0.94 | 19 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0006897 | Biological process | endocytosis |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0005764 | Cellular component | lysosome |
| GO_0005768 | Cellular component | endosome |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | MARCHF3 |
| Protein name | E3 ubiquitin-protein ligase MARCHF3 (EC 2.3.2.27) (Membrane-associated RING finger protein 3) (Membrane-associated RING-CH protein III) (MARCH-III) (RING finger protein 173) (RING-type E3 ubiquitin transferase MARCHF3) |
| Synonyms | RNF173 MARCH3 |
| Description | FUNCTION: E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. . |
| Accessions | Q86UD3 ENST00000515241.1 [Q86UD3-2] ENST00000308660.6 [Q86UD3-1] |