MARCHF3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0006897Biological processendocytosis
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0031901Cellular componentearly endosome membrane
GO_0005764Cellular componentlysosome
GO_0005768Cellular componentendosome
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameMARCHF3
Protein nameE3 ubiquitin-protein ligase MARCHF3 (EC 2.3.2.27) (Membrane-associated RING finger protein 3) (Membrane-associated RING-CH protein III) (MARCH-III) (RING finger protein 173) (RING-type E3 ubiquitin transferase MARCHF3)
SynonymsRNF173
MARCH3
DescriptionFUNCTION: E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. .

AccessionsQ86UD3
ENST00000515241.1 [Q86UD3-2]
ENST00000308660.6 [Q86UD3-1]