I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 21% ± 4% | |
| epithelial cell | 3 studies | 28% ± 11% | |
| dendritic cell | 3 studies | 25% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 21% ± 4% | |
| epithelial cell | 3 studies | 28% ± 11% | |
| dendritic cell | 3 studies | 25% ± 9% |
Insufficient scRNA-seq data for expression of MAP1S at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 2230.52 | 180 / 180 | 100% | 56.55 | 430 / 430 |
| thymus | 100% | 1821.31 | 652 / 653 | 100% | 25.45 | 604 / 605 |
| esophagus | 100% | 1800.67 | 1440 / 1445 | 100% | 38.98 | 183 / 183 |
| stomach | 100% | 1648.50 | 359 / 359 | 100% | 36.32 | 285 / 286 |
| intestine | 100% | 2093.88 | 966 / 966 | 99% | 33.12 | 524 / 527 |
| brain | 100% | 2631.18 | 2631 / 2642 | 100% | 33.03 | 703 / 705 |
| prostate | 100% | 1908.08 | 245 / 245 | 99% | 22.35 | 497 / 502 |
| skin | 100% | 1588.81 | 1803 / 1809 | 99% | 33.17 | 467 / 472 |
| breast | 100% | 2164.08 | 459 / 459 | 98% | 23.67 | 1101 / 1118 |
| bladder | 100% | 2247.43 | 21 / 21 | 98% | 24.86 | 495 / 504 |
| kidney | 100% | 1375.60 | 89 / 89 | 98% | 19.18 | 884 / 901 |
| lung | 100% | 2569.97 | 577 / 578 | 98% | 25.31 | 1131 / 1155 |
| uterus | 100% | 2448.50 | 170 / 170 | 97% | 22.80 | 445 / 459 |
| adrenal gland | 99% | 1284.06 | 256 / 258 | 97% | 24.10 | 224 / 230 |
| pancreas | 96% | 888.12 | 314 / 328 | 100% | 26.81 | 178 / 178 |
| liver | 85% | 588.95 | 192 / 226 | 91% | 12.62 | 370 / 406 |
| adipose | 100% | 2167.45 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 32.57 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 32.38 | 29 / 29 |
| muscle | 100% | 1964.23 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1946.05 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 19.90 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.68 | 1 / 1 |
| blood vessel | 100% | 2533.28 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 2388.22 | 915 / 929 | 0% | 0 | 0 / 0 |
| heart | 97% | 1073.64 | 837 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007052 | Biological process | mitotic spindle organization |
| GO_0051310 | Biological process | metaphase chromosome alignment |
| GO_0047497 | Biological process | mitochondrion transport along microtubule |
| GO_0031114 | Biological process | regulation of microtubule depolymerization |
| GO_0007409 | Biological process | axonogenesis |
| GO_0048812 | Biological process | neuron projection morphogenesis |
| GO_0000226 | Biological process | microtubule cytoskeleton organization |
| GO_0007420 | Biological process | brain development |
| GO_0006915 | Biological process | apoptotic process |
| GO_0006914 | Biological process | autophagy |
| GO_0034454 | Biological process | microtubule anchoring at centrosome |
| GO_0007399 | Biological process | nervous system development |
| GO_0016358 | Biological process | dendrite development |
| GO_0001578 | Biological process | microtubule bundle formation |
| GO_0005730 | Cellular component | nucleolus |
| GO_1990498 | Cellular component | mitotic spindle microtubule |
| GO_0005874 | Cellular component | microtubule |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005813 | Cellular component | centrosome |
| GO_0005815 | Cellular component | microtubule organizing center |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0030425 | Cellular component | dendrite |
| GO_0005829 | Cellular component | cytosol |
| GO_0045202 | Cellular component | synapse |
| GO_0042995 | Cellular component | cell projection |
| GO_0030054 | Cellular component | cell junction |
| GO_0005875 | Cellular component | microtubule associated complex |
| GO_0005819 | Cellular component | spindle |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0004536 | Molecular function | DNA nuclease activity |
| GO_0048487 | Molecular function | beta-tubulin binding |
| GO_0015631 | Molecular function | tubulin binding |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0003779 | Molecular function | actin binding |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MAP1S |
| Protein name | Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) (Variable charge Y chromosome 2-interacting protein 1) (VCY2-interacting protein 1) (VCY2IP-1) [Cleaved into: MAP1S heavy chain; MAP1S light chain] Microtubule associated protein 1S |
| Synonyms | BPY2IP1 VCY2IP1 C19orf5 MAP8 |
| Description | FUNCTION: Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity). . |
| Accessions | ENST00000593593.5 ENST00000594365.5 ENST00000324096.9 [Q66K74-1] ENST00000596637.5 ENST00000600186.5 ENST00000597000.1 Q66K74 M0QX37 ENST00000594625.5 M0QXE8 M0QXQ9 M0QY41 ENST00000594212.5 M0R1J2 M0R1M7 ENST00000600608.5 M0QYI5 M0QXK6 M0QZ50 ENST00000544059.2 [Q66K74-2] ENST00000597735.5 |
